Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,343 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06782555RecruitingPhase 1/Phase 2
Study of experimental drug combo for advanced cancers
This trial tests a new combination of three drugs—evofosfamide, zalifrelimab, and balstilimab—in people with advanced prostate, pancreatic, or certain head and neck cancers that have stopped responding to standard treatments.
Houston, TexasAges 18 years+ - NCT06782581Recruiting
Cancer Support Study for Asian Americans and Their Caregivers
This study explores how relationships and support can help Asian American cancer patients and their caregivers. You and a caregiver would join a program to improve communication and coping during cancer treatment.
Philadelphia, PennsylvaniaAges 21–80 - NCT06783244Recruiting
Low vs standard belly pressure for robot colorectal cancer surgery
This trial is testing whether using lower air pressure inside the belly during robot-assisted colorectal cancer surgery helps patients recover better compared to the standard pressure. It aims to find a gentler approach that might reduce pain and improve recovery.
Copenhagen NVAges 18 years+ - NCT06783348RecruitingPhase 2
Radioactive treatment for advanced kidney cancer
This trial tests a radioactive treatment (called radiopharmaceutical) that targets a protein called PSMA on kidney cancer cells. It is for people with advanced clear cell kidney cancer that has already been treated with immunotherapy and targeted therapy.
CaenAges 18–100 - NCT06783491RecruitingPhase 3
Chemotherapy with or without heated chemo for advanced colon cancer
This trial tests if adding heated chemotherapy directly into the abdomen during surgery improves outcomes for people with advanced colon cancer that hasn't spread to other organs. It compares standard chemotherapy before surgery alone versus chemotherapy before surgery plus heated chemo during surgery.
Córdoba, CórdobaAges 18–75 - NCT06783829RecruitingPhase 1
Study of SHR-4394 for men with advanced prostate cancer
This trial tests a new drug, SHR-4394, for men with prostate cancer that has spread to other parts of the body and is no longer responding to current treatments. The goal is to see if this drug can help slow down the cancer.
Chengdu, SichuanAges 18–85 - NCT06784765Recruiting
Preventive PIPAC for advanced stomach cancer
This trial tests if a special type of chemotherapy delivered as a mist during surgery (PIPAC) can help prevent the spread of stomach cancer. It is for people with advanced but not yet metastatic stomach cancer who have not had prior treatment.
AstanaAges 18 years+ - NCT06784791RecruitingPhase 2
Amivantamab before surgery for EGFR-mutant lung cancer
This trial tests a new drug, amivantamab, given before surgery for people with a specific EGFR-mutated lung cancer. It aims to shrink tumors and improve surgical outcomes, and may be combined with standard chemotherapy in some patients.
HasseltAges 18 years+ - NCT06785051Recruiting
AI physiotherapy for oral cancer patients
This study tests an AI-based physiotherapy program for people with newly diagnosed oral cancer. It aims to help patients maintain or improve their movement during cancer treatment, such as surgery, chemotherapy, or radiation.
TaipeiAges 20–65 - NCT06785077Recruiting
Genetic Study in Ovarian Cancer During PARP Inhibitor Therapy
This study looks at the genetic changes in ovarian cancer cells before and during treatment with PARP inhibitors. It aims to understand how these changes may affect treatment response.
MilanAges 18 years+ - NCT06786949Recruiting
Night shift work and breast cancer risk study
This study looks at whether working night shifts is linked to breast cancer in female health workers. It aims to understand if there is a higher risk for those who work nights.
BolognaAges 20–70 - NCT06787053Recruiting
MRI imaging for oxygen-starved tumors
This study uses MRI scans to find areas of low oxygen in tumors and see if adjusting radiation treatment can help. It is open to adults with bladder, cervix, or prostate cancer who are getting radiation therapy at the Christie NHS Foundation Trust.
ManchesterAges 18 years+ - NCT06787313Recruiting
Precision palliative care for advanced esophageal cancer
This trial studies a personalized approach to palliative care for people with advanced or recurrent esophageal cancer who are being treated with immunotherapy. It aims to improve quality of life and symptom management.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06787625Recruiting
Growing tumor models from colorectal cancer and liver metastases
This study takes samples from colorectal cancer that has spread to the liver and grows them in the lab. The goal is to create models that can help researchers understand the cancer better and find new treatments.
RomeAges 18 years+ - NCT06787911RecruitingPhase 2
Donafenib and immunotherapy before surgery for advanced thyroid cancer
This trial tests a combination of two drugs—donafenib (a targeted therapy) and an immunotherapy (anti-PD-1 antibody)—given before surgery for locally advanced differentiated thyroid cancer. The goal is to shrink the tumor to make surgery easier and more complete. If you have this type of thyroid cancer that is hard to remove completely with surgery alone, this study may be an option.
ShanghaiAges 18–80 - NCT06788366Recruiting
AI tool to predict outcomes in metastatic lung cancer
This trial is testing whether artificial intelligence can help predict how well people with advanced non-small cell lung cancer (NSCLC) respond to immunotherapy or chemo-immunotherapy. If you have stage IV NSCLC and have started this treatment, your data may help build a better prediction tool.
MilanAges 18 years+ - NCT06788548Recruiting
Fluorescence-Guided Surgery for Early Stomach Cancer
This trial tests a new technique that uses a special dye to highlight the first lymph nodes where stomach cancer might spread, allowing surgeons to remove only the necessary nodes during surgery. The goal is to reduce side effects while still effectively treating the cancer.
Beijing, Beijing MunicipalityAges 18–80 - NCT06789848RecruitingPhase 2
Testing two immunotherapy drugs for advanced liver and bile duct cancers
This trial tests two investigational drugs, ligufalimab and cadonilimab, for people with advanced liver cancer (hepatocellular carcinoma, HCC) or bile duct cancer (biliary tract cancer, BTC) that has not responded to previous treatment with an immunotherapy drug. The goal is to see if this combination can shrink tumors or slow cancer growth.
Dallas, TexasAges 18 years+ - NCT06791005RecruitingPhase 3
Timing of carbon nanoparticles injection for thyroid cancer
This trial tests whether the timing of a carbon nanoparticle injection during thyroid cancer surgery improves outcomes. It may help patients who need their whole thyroid removed and have cancer in both lobes or spread to lymph nodes.
Xi'an, ShaanxiAges 16–80 - NCT06791083RecruitingPhase 2
Envafolimab, Fruquintinib, and chemo before gastric cancer surgery
This trial tests a combination of two targeted drugs (Envafolimab and Fruquintinib) plus chemotherapy given before surgery for certain types of stomach cancer. The goal is to see if this approach can shrink the tumor and improve outcomes.
Fuzhou, FujianAges 18–75 - NCT06791148RecruitingPhase 2
Low-dose radiation plus chemo and immunotherapy for advanced stomach cancer
This trial tests a combination of low-dose radiation, chemotherapy, and an immunotherapy drug (AK112) for people with advanced stomach or gastroesophageal junction cancer that has progressed after first-line treatment. The goal is to see if this combination can help shrink tumors or slow the cancer's growth.
Nanjing, JiangsuAges 18–75 - NCT06791941Recruiting
Studying therapy resistance in recurrent head and neck cancer
This study looks at why some head and neck cancers come back after treatment. It will test tumor tissue from people having surgery to see if certain proteins (mutant p53 and YAP) are linked to treatment resistance. Your participation could help researchers understand how to better treat these cancers in the future.
Roma, RomeAges 18 years+ - NCT06792162RecruitingPhase 2
Immunotherapy and targeted therapy trial for advanced gastric cancer
This trial tests a combination of two drugs: carilizumab (an immunotherapy) and apatinib (a targeted therapy) for patients with unresectable stage III or IV gastric cancer that has a specific DNA repair problem (dMMR). The goal is to see if this treatment can help shrink tumors and improve outcomes.
BeijingAges 18 years+ - NCT06792604Recruiting
Methylation test for anal cancer screening
This study is testing a new way to screen for anal cancer by looking at DNA methylation in cells collected from the anus. It may help people at higher risk for anal cancer find out earlier if they need further tests.
Paris, Île-de-France RegionAges 18 years+
Hear when a new Cancer (With or Without Metastasis) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,343 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.