Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,078 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04676828Recruiting
SPECT-guided radiation to avoid healthy lung in lung cancer
This study tests a special imaging-guided radiation plan that aims to treat lung cancer while reducing radiation to healthy lung tissue. It may help lower lung side effects while keeping the cancer treatment focused on tumor areas.
Sydney, New South WalesAges 18 years+ - NCT04657042Recruiting
4D MRI scans to guide lung or liver cancer radiation
This trial tests whether special “4D” MRI scans can improve precision radiation planning for people with lung or liver cancer. You may get MRI scan data to better account for tumor movement, alongside your usual radiation treatment.
Charlottesville, VirginiaAges 18–82 - NCT04643366RecruitingPhase 2
Total treatment with chemotherapy and short radiation before surgery
This trial tests whether combining chemotherapy (mFOLFOX6) and a short course of radiation before surgery improves outcomes for people with resectable rectal cancer. The goal is to shrink and control the cancer early and then remove it with curative surgery.
Richmond, VirginiaAges 18 years+ - NCT04671940Recruiting
Study tumor DNA changes during robot surgery after radiation
This study looks at how a cancer’s DNA changes over time in people who had head and neck cancer treated with radiation and then need robot-assisted surgery. It may help doctors understand why some cancers come back or persist and how to better plan treatment.
LondonAges 19 years+ - NCT04557969Recruiting
Surgery and tumor testing in gastrointestinal stromal tumors (GIST)
This study looks at how surgery for gastrointestinal stromal tumors (GIST) works, and collects tumor samples to study them under the microscope and by DNA testing. Your results may help researchers better predict tumor behavior and guide future treatment.
Bethesda, MarylandAges 6 years+ - NCT04588025Recruiting
MRI study using a special model to measure pancreatic cancer response
This study tests a new, harmless “disposable” setup for MRI scans to measure how pancreatic cancer treatments affect the body. It may help doctors get more accurate MRI measurements, so treatment response can be assessed better.
Columbus, OhioAges 19 years+ - NCT04510636RecruitingPhase 2
Pembrolizumab and bendamustine for Hodgkin lymphoma
This study tests whether combining the immunotherapy drug pembrolizumab (Keytruda) with the chemotherapy bendamustine can help people with Hodgkin lymphoma whose cancer returned or did not respond to earlier treatment. The goal is to see if this two-drug combination works better than either drug alone.
Toronto, OntarioAges 18 years+ - NCT04517266Recruiting
Testing less radiation to the inner breast area
This trial studies whether some patients with early-stage breast cancer can safely skip a specific part of radiation to the inner chest (called internal mammary irradiation). It may reduce radiation side effects while still aiming to prevent the cancer from coming back.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT04595422Recruiting
Train quitline staff to reach smokers about lung screening
This trial tests an educational approach delivered through tobacco quitlines to encourage eligible smokers to learn about lung cancer screening. It may help people who have a heavy smoking history get the right information and next steps.
Houston, TexasAges 18 years+ - NCT04551378Recruiting
Study of how COVID affected young people with cancer
This study looks at how the COVID-19 pandemic affected the experiences of teenagers and young adults with cancer, including people who finished treatment. It may help improve support for cancer patients and survivors during public health crises.
Houston, TexasAges 18–39 - NCT04588402Recruiting
Tests whether HPV vaccination prevents cervical HPV infection in young women
This study looks at whether HPV vaccination lowers the chance of getting HPV in the cervix. It will collect cervical samples and ask questions to see how vaccination affects infection in women in Sikkim, India.
Gangtok, SikkimAges 18–22 - NCT04589624RecruitingPhase 1
MRI scan to monitor response in head and neck cancers
This Phase 1 study tests an investigational MRI scan (hpMRI) to help doctors see how thyroid cancer and other head-and-neck cancers respond to treatment like radiation or other medicines. If you’re eligible, the scan may help track treatment effects more closely, though it’s still being studied for this purpose.
Houston, TexasAges 18 years+ - NCT04556916Recruiting
Early prostate cancer screening with MRI before biopsy
This study is testing an approach to find prostate cancer earlier in men who may be at higher risk. If you fit the criteria, you may get an mpMRI scan before undergoing a prostate biopsy to check for cancer.
MontpellierAges 40 years+ - NCT04525989Recruiting
Short-course proton vs photon radiation before rectal surgery
This study compares two types of pre-surgery radiation—protons versus standard photons—in people with high-risk rectal cancer. The goal is to shrink and control the tumor while safely getting you ready for surgery, and to see which approach works better.
Stockholm, SolnaAges 18 years+ - NCT04574960RecruitingPhase 3
Neoadjuvant chemotherapy before kidney/ureter cancer surgery
This Phase 3 trial studies giving cisplatin-based chemotherapy before surgery for certain newly diagnosed upper-urinary-tract urothelial cancers (kidney/ureter). It may help shrink the cancer and improve outcomes by treating microscopic disease earlier.
Ottawa, OntarioAges 18 years+ - NCT04491292Recruiting
COVID-19 impact survey for MD Anderson workers
This study asks MD Anderson employees about how the COVID-19 pandemic affected their mental and emotional well-being. Your answers may help the team understand workplace needs during and after major public health events.
Houston, TexasAges 18 years+ - NCT04534413Enrolling by invitation
Test lung cancer samples outside the body during surgery
This study looks at lung cancer tissue after surgery, using lab testing done outside the body. It may help researchers better observe and study lung tumors using samples taken during lobectomy or segment removal.
Toronto, OntarioAges 18 years+ - NCT04541654Recruiting
Study of families with TP53 gene changes in Li-Fraumeni syndrome
This study is looking at how people in families with certain TP53 gene changes (including Li-Fraumeni syndrome) develop health problems over time. It may help doctors better understand risk and improve care for affected families.
Boston, MassachusettsAges Any age - NCT04488614Enrolling by invitation
Biobank study for early-stage breast cancer samples
This study collects and stores biological samples (like tissue or blood) from people with early-stage breast cancer to help future research. It’s mainly for people with a specific type of early breast cancer called high-grade DCIS.
Stavanger, RogalandAges 18–85 - NCT04449549RecruitingPhase 2
Nilotinib and paclitaxel for rare solid tumors
This study tests a combination of two drugs, nilotinib and paclitaxel, in people with certain rare cancers that have not responded to standard treatments. It aims to see if this combination can shrink tumors or slow cancer growth.
Bethesda, MarylandAges 18–120 - NCT04431024Recruiting
Testing imaging and biopsy options for people with BAP1 risk
This study looks at how well advanced scans, liquid biopsy tests, and small follow-up procedures can find early mesothelioma in people with a high-risk BAP1 gene condition. It may help catch cancer earlier when treatment could work better.
Bethesda, MarylandAges 30–120 - NCT04486352RecruitingPhase 1/Phase 2
Targeted therapy trial for recurrent or persistent endometrial cancer
This Phase 1/2 study tests targeted drug(s) for endometrial cancer that has come back or never fully went away after prior treatments. You may be eligible if your tumor can be tested for specific biomarkers and your health allows treatment safely.
Duarte, CaliforniaAges 18 years+ - NCT04469764RecruitingPhase 2
Abemaciclib for certain recurrent ovarian or endometrial cancers
This Phase 2 study tests abemaciclib, a targeted pill treatment, for recurrent ovarian or endometrial cancer that shows specific tumor genetic patterns. It may help slow or control cancer growth in people whose tumor matches the required test results.
Los Angeles, CaliforniaAges Any age - NCT04409340Recruiting
Imaging test for liver cancer
This study uses a special MRI technique to look at liver tumors more clearly. It may help doctors better understand and diagnose liver cancer without extra procedures.
Montreal, QuebecAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,078 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.