Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,052 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06414148RecruitingPhase 2
Epcoritamab with or without lenalidomide and rituximab after CAR T
This trial tests whether adding a drug called epcoritamab (with or without two other drugs, lenalidomide and rituximab) can help people with large B-cell lymphoma whose cancer was still detectable after CAR T-cell therapy. It aims to stop the cancer from coming back.
Camperdown, New South WalesAges 16 years+ - NCT06878612RecruitingPhase 1
Personalized tumor cell vaccine for advanced solid tumors
This trial tests a new vaccine made from your own tumor cells to see if it can help your immune system fight the cancer. It is for people with advanced solid tumors that have not responded to other treatments.
Chengdu, SichuanAges 18–65 - NCT06976710Recruiting
Improving communication before colon or rectal cancer surgery
This trial is testing a way to improve communication between you and your surgical team before colon or rectal cancer surgery. It's for adults having major surgery that aims to cure their cancer.
Coffs Harbour, New South WalesAges 18 years+ - NCT06972615RecruitingPhase 2
Bladder chemo plus pembrolizumab for BCG-treated cancer
This trial tests a combination of chemotherapy placed directly into the bladder and an immunotherapy drug called pembrolizumab (given through a vein) for people with high-risk bladder cancer that has not completely responded to or has returned after BCG treatment.
CABAAges 18 years+ - NCT06975293RecruitingPhase 1/Phase 2
STC-15 with toripalimab for advanced cancers and sarcomas
This trial tests a new drug called STC-15, either alone or with another drug (toripalimab), for people with certain advanced cancers or sarcomas that have progressed after prior treatment. The goal is to see if this combination or single drug can help shrink tumors or slow the disease.
San Francisco, CaliforniaAges 18 years+ - NCT06914349Recruiting
Comparing two ways to reconnect the stomach after Whipple surgery
This trial compares two common surgical techniques for reconnecting the stomach and small intestine during a Whipple procedure (pancreaticoduodenectomy) to see if one leads to fewer complications. It may help surgeons choose the best approach for you.
LarissaAges 18–80 - NCT06977503Recruiting
Electrical stimulation with life coaching for burnout in healthcare workers
This study tests whether a gentle electrical headband used at home, plus online life coaching, can help reduce burnout symptoms in healthcare workers. You would attend three in-person visits and join group coaching sessions over about 15 weeks.
Buffalo, New YorkAges 21–75 - NCT06977698Recruiting
Detecting cancer margins during breast surgery
This study tests a new method to check for leftover cancer cells and lymph node spread during breast surgery. It may help doctors make sure all cancer is removed the first time.
NottinghamAges Any age - NCT06973668RecruitingPhase 2
Comparing drug combos to prevent graft versus host disease after stem cell transplant
This trial tests if a drug combo (cyclophosphamide, sirolimus, and ruxolitinib) works better than another combo (cyclophosphamide, sirolimus, and mycophenolate mofetil) to prevent graft versus host disease in people getting a stem cell transplant for certain blood cancers.
Houston, TexasAges 65–75 - NCT06980259Recruiting
Comparing two types of radiation for soft tissue sarcoma
This trial tests a newer way of giving radiation (spatially fractionated) compared to standard radiation for people with large soft tissue sarcomas. It aims to see if the new method works better.
Jinan, ShandongAges 18–70 - NCT06974370RecruitingPhase 2
Avoiding brain radiation when chemo or other drugs work
This trial tests whether some people with brain metastases from solid tumors can safely skip radiation if their cancer drugs (like targeted therapy, immunotherapy, or certain chemotherapies) shrink the brain tumors. You will get MRI scans to see if the drugs are working.
Burlington, VermontAges 18 years+ - NCT06982469Recruiting
High-dose radiation for prostate cancer return after surgery
This trial tests a high-dose radiation treatment (brachytherapy) that places tiny radioactive seeds directly into the area where your prostate was. It is for men whose prostate cancer has returned only in that area after having their prostate removed.
Pamplona, Foral Community of NavarreAges 18–80 - NCT06979869Recruiting
Esophageal cancer gene test for treatment response
This trial uses a blood test to track genetic changes in esophageal cancer over time. It aims to see if these changes can show how well treatment is working.
Wuwei, GansuAges 18–75 - NCT06976476RecruitingPhase 2
IgPro20 to prevent infections in multiple myeloma patients on bispecific therapy
This study tests whether a weekly infusion of a blood product called IgPro20 can help prevent infections in people with multiple myeloma who are already being treated with a bispecific antibody. If you qualify, you will receive the study treatment and be monitored for safety and infection rates.
Atlanta, GeorgiaAges 18 years+ - NCT06981026Recruiting
Checking if remote health coaching helps before prostate surgery
This study tests whether using a smartphone or computer to get health coaching before prostate cancer surgery helps people recover faster and have better results. You will be asked to exercise and track your health at home while staying connected with your care team.
OlomoucAges 40–80 - NCT06972875RecruitingPhase 2
Testing a hot flash pill for men on prostate cancer therapy
This trial tests a non-hormonal pill called fezolinetant to reduce hot flashes in men with prostate cancer who are on hormone therapy. If you have daily, bothersome hot flashes, this study may help you find relief.
Burlington, VermontAges 18 years+ - NCT06929936RecruitingPhase 2
Trilaciclib plus docetaxel for advanced lung cancer (second-line+)
This trial tests a new drug combination (trilaciclib plus docetaxel) for people with advanced lung cancer (NSCLC) whose cancer has progressed after at least one prior treatment. The goal is to see if adding trilaciclib helps the chemotherapy work better with fewer side effects.
Xiamen, FujianAges 18 years+ - NCT05936736Recruiting
One-time radiation for prostate cancer with bladder-sparing approach
This trial tests whether giving prostate radiation in one treatment session can work well while protecting the bladder. It may help certain people with localized prostate cancer by aiming for good cancer control with fewer bladder/urinary side effects.
Milan, MIAges 18 years+ - NCT06005324RecruitingPhase 1
Personalized treatment for advanced head and neck cancer
This trial tests a custom treatment plan for people with advanced head and neck cancer that is not caused by HPV. It combines radiation and chemotherapy with a targeted drug called cetuximab, adjusted based on your tumor's characteristics.
Chicago, IllinoisAges 18 years+ - NCT06967740Recruiting
Precancerous Lesions of the Cervix: Better Care Options
This study looks at better ways to manage early precancerous changes in the cervix (called high-grade lesions) without surgery. It aims to find which approaches work best for women who have not been vaccinated against HPV.
PragueAges 18–46 - NCT06962865RecruitingPhase 2
RC108 and Furmonertinib for first-line treatment of EGFR-mutated and MET-positive NSCLC
This trial tests whether a combination of two drugs, RC108 and Furmonertinib, can help people with non-small cell lung cancer (NSCLC) that has specific genetic changes (EGFR mutation and MET positivity) and cannot be removed by surgery. It is for people who have not yet received treatment for their advanced or metastatic cancer.
BeijingAges 18–75 - NCT06963814RecruitingPhase 1
HC006 with a PD-1 inhibitor for advanced solid tumors
This trial tests a new drug called HC006 combined with a standard immunotherapy (PD-1 inhibitor) for people with advanced solid tumors. It aims to see if the combination is safe and effective.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06966700RecruitingPhase 3
Study of Sac-TMT in Early High-Risk Breast Cancer
This study tests a new drug called Sacituzumab Tirumotecan (Sac-TMT) for people with early-stage, high-risk breast cancer that hasn't spread. The drug is given before surgery to see if it can shrink tumors and improve outcomes.
Gilbert, ArizonaAges 18 years+ - NCT06971614RecruitingPhase 2
T3011 for bladder cancer not responding to standard treatments
This trial tests a drug called T3011 for a type of bladder cancer that hasn't responded to standard treatments like BCG or chemotherapy. It aims to see if T3011 can help shrink the cancer or keep it from growing, offering a new option for people who have limited choices.
Queen Creek, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,052 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.