Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,042 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03349762Recruiting
Huaier granules to help prevent colorectal cancer coming back
This study tests whether Huaier granules after surgery can lower the chance that colorectal cancer returns or spreads. It is for people who have recently had “radical” (complete) surgery for certain stages of colorectal cancer and are within about 2 months of that surgery.
Shijiazhuang, HebeiAges 18–75 - NCT05059951Recruiting
Chemotherapy With or Without Immunotherapy for Lung Cancer
This trial looks at whether adding an immunotherapy drug (an immune checkpoint inhibitor) to chemotherapy helps people with lung cancer live better or respond better. You might be considered if your cancer is confirmed, you can tolerate treatment, and imaging shows measurable spots.
Changsha, HunanAges 18 years+ - NCT07815834RecruitingPhase 3
FAPI-guided radiation with cadonilimab and chemo for colorectal cancer spread to the abdomen
This trial tests a new combination treatment for colorectal cancer that has spread only to the lining of the abdomen (peritoneum). It combines targeted radiation, an immunotherapy drug called cadonilimab, and standard chemotherapy to see if it can help control the disease better than current options.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06244264Recruiting
Using your own blood during spine surgery for lung cancer
This study tests the safety and effectiveness of using your own blood (collected before surgery) during spine surgery for lung cancer that has spread to the backbone. It may help people whose spine is unstable or causing nerve problems.
Guangzhou, GuangdongAges 18–75 - NCT06086457RecruitingPhase 3
Immunotherapy plus chemo with or without radiation for esophageal cancer
This trial tests whether adding radiation therapy to a standard treatment (immunotherapy plus chemotherapy) can help people with advanced esophageal cancer that has spread to up to two organs. The goal is to see if the combination improves outcomes.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07793500RecruitingEarly Phase 1
Nebulized drug for lung metastases from solid tumors
This study tests a new drug given as a mist you breathe in, for people whose cancer has spread to the lungs. The goal is to see if it can shrink tumors or slow their growth.
BeijingAges 18–75 - NCT06531278RecruitingPhase 2
Adebelimab plus chemo for first-line pancreatic cancer with liver spread
This trial tests a combination of immunotherapy (adebelimab) and chemotherapy drugs (irinotecan liposome, oxaliplatin, fluorouracil, and calcium folinate) as a first treatment for pancreatic cancer that has spread to the liver. The goal is to see if this combination is safe and effective.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06531460Recruiting
Omega-3 nutrition before lung cancer surgery
This study tests whether a special nutrition drink with omega-3 (a healthy fat found in fish) can help people recover better after lung cancer surgery. You may qualify if you are about to have lung removal surgery.
Mexico CityAges 18 years+ - NCT07789210RecruitingPhase 2
Neoadjuvant targeted therapy for BRAF-mutant colorectal cancer
This trial is testing a combination of two targeted drugs (encorafenib and cetuximab) with standard chemotherapy before surgery in people with a specific type of colorectal cancer that has the BRAF V600E mutation and is locally advanced or has limited spread. The goal is to see if this treatment can shrink tumors and improve outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT07790510RecruitingPhase 1/Phase 2
Study of HSK42360 with cetuximab for BRAF-mutated colorectal cancer
This trial tests an experimental drug (HSK42360-Na) combined with standard treatments (cetuximab with or without chemotherapy) for people with advanced colorectal cancer that has a specific BRAF mutation. The goal is to see if this combination can shrink tumors or slow their growth, and to check its safety.
BeijingAges 18 years+ - NCT06185556RecruitingPhase 2/Phase 3
New treatments for liver tumors near blood vessels or bile ducts
This trial tests two procedures—irreversible electroporation and stereotactic body radiotherapy—for people whose colorectal cancer has spread to the liver (1–3 tumors near major blood vessels or bile ducts) and can't be surgically removed or treated with heat. The goal is to see if these approaches can safely destroy those hard-to-reach tumors.
Amsterdam, North HollandAges 18 years+ - NCT06585007RecruitingPhase 3
Radiation for limited cancer growth in castration-resistant prostate cancer
This trial tests whether giving focused radiation to limited areas of cancer growth (up to 3 spots) can help control the disease in men with castration-resistant prostate cancer. You may be eligible if your cancer is growing slowly and you are already on hormone therapy.
LeuvenAges 18 years+ - NCT07740239Recruiting
Study on frailty in seriously ill adults
This study looks at why some seriously ill adults become frail. It involves imaging and other tests to help doctors better understand and care for patients with serious conditions.
TampereAges Any age - NCT07738172RecruitingPhase 3
Osimertinib with or without lung tumor surgery for EGFR-mutated non-small cell lung cancer
This study tests whether adding surgery to remove the main lung tumor improves outcomes for people with stage 4 lung cancer that has a specific EGFR mutation and only limited spread. If you qualify, you will take the targeted drug osimertinib for 12 weeks, and if the tumor responds, you may be randomly assigned to either continue the drug alone or have the main tumor surgically removed and then continue the drug.
Taipei, Taipei CityAges 18 years+ - NCT06619002Recruiting
Using video to make uterine cancer surgery safer
This study is collecting videos from a type of minimally invasive surgery called sentinel lymph node dissection for endometrial or cervical cancer. The goal is to use deep learning (a type of artificial intelligence) to help surgeons identify important structures and any spread of cancer during the procedure, making the surgery safer and more effective.
RomaAges 18–99 - NCT05250648RecruitingPhase 4
HIPEC with mitomycin C after surgery for colon cancer in the belly
This study looks at adding a heated medicine treatment (HIPEC with mitomycin C) during surgery to treat colon cancer that has spread to the lining of the abdomen (peritoneum). It aims to improve outcomes after surgeons remove visible tumor completely.
Elche, AlicanteAges 18 years+ - NCT06646341Recruiting
Can scan findings predict colorectal cancer spread?
This study looks at whether signs of blood vessel involvement (called EMVI) seen on scans can predict if colorectal cancer spreads to other organs. You might join if you already had surgery to remove the cancer from the colon or rectum and any distant tumors, and your before-surgery scans are available for review.
Basingstoke, HampshireAges 16–100 - NCT06676761Recruiting
Study of a new minimal scar mastectomy
This trial is testing a new surgical technique that leaves a smaller scar during mastectomy for breast cancer. It may be a good option if you want to keep the scar as small as possible.
SingaporeAges Any age - NCT07655583RecruitingPhase 1
Skipping radiation after brain surgery
This study is for people with melanoma or lung cancer that has spread to the brain and who have had surgery to remove the brain tumor. It looks at whether it is safe to skip the usual radiation treatment after surgery, while taking a targeted drug therapy that is known to be effective in the brain.
Houston, TexasAges 18 years+ - NCT07660276Enrolling by invitation
AI predicts prostate cancer spread from biopsy
This study uses an artificial intelligence (AI) system to look at prostate biopsy samples and predict if the cancer has spread to the lymph nodes. It may help doctors decide on the best treatment without needing extra surgery or scans.
Changsha, HunanAges 18–90 - NCT07653685RecruitingPhase 1/Phase 2
Study of a new drug with chemotherapy for advanced colorectal cancer
This trial tests a new drug (TQB2930) combined with chemotherapy, with or without another drug called bevacizumab, for people whose colorectal cancer has spread or cannot be removed by surgery and has a specific protein called HER2. The goal is to see if this combination can help shrink tumors or slow the cancer's growth.
Beijing, Beijing MunicipalityAges 18–75 - NCT07644286RecruitingPhase 2
Pirfenidone and immunotherapy with optional radiation for advanced colorectal cancer
This study tests a combination of three treatments—pirfenidone (an anti-scarring drug), a PD-1 inhibitor (an immunotherapy that helps your immune system fight cancer), and sometimes radiation—for colorectal cancer that has stopped responding to standard treatments. The goal is to see if this combination can slow or shrink your cancer.
Wuhan, HubeiAges 18–75 - NCT07645625RecruitingPhase 4
Pembrolizumab outcomes study in cervical cancer
This study tracks how well pembrolizumab works in people with cervical cancer that has come back, spread, or not gone away. It includes two groups: one for those currently on or starting the drug, and one for those who stop early due to a good response or side effects.
AmsterdamAges 18 years+ - NCT05000697Recruiting
Watch-and-wait or chemo after rectal cancer radiation
This trial studies people with early-to-mid stage distal rectal cancer who may get radiation and chemotherapy, with an option that may include an extra drug (oxaliplatin). It also tests whether some people can safely follow a “watch and wait” plan instead of immediate additional treatment, aiming to reduce overtreatment while keeping cancer control.
Buenos AiresAges 18 years+
Hear when a new Cancer (With or Without Metastasis) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,042 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.