Clinical trials · Maryland
Cancer clinical trials in Maryland
We’re tracking 707 recruiting cancer studies with a site in Maryland — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Maryland
- NCT06303193RecruitingPhase 1/Phase 2
Testing a kinase inhibitor drug for MDS and MDS/MPN in adults and teens
This trial tests a drug called pacritinib in people with myelodysplastic syndromes (MDS) or MDS/myeloproliferative neoplasms (MDS/MPN). The drug targets several proteins that may help control the disease, especially for those who have not responded to other treatments.
Bethesda, MarylandAges 12–120 - NCT05621291Recruiting
Sequencing test to guide care after CD19 CAR T in kids
This study checks a DNA-based lab test (next-generation sequencing, or NGS) to monitor B-cell recovery after CD19 CAR T treatment in children and young adults. The goal is to see whether the test can help guide management while looking for remission and safe recovery.
Bethesda, MarylandAges 1–25 - NCT07672483RecruitingPhase 1
Gene therapy for solid tumors that returned after treatment
This trial tests a new type of gene therapy that uses your own immune cells (called myeloid cells) engineered to produce a protein (IL-12) to fight your cancer. It is for people with solid tumors that have not responded to standard treatments.
Bethesda, MarylandAges 18–120 - NCT07572136RecruitingPhase 1
CAR T-cell therapy for hard-to-treat B-cell leukemia
This trial tests a new type of CAR T-cell therapy—a treatment that uses your own immune cells engineered to fight leukemia cells. It is designed for patients with B-cell acute lymphoblastic leukemia (ALL) that has come back or stopped responding to standard treatments, and whose leukemia cells have a specific marker called TSLPR.
Bethesda, MarylandAges 18–120 - NCT06623422RecruitingPhase 3
Vaccine plus Keytruda for lung cancer after surgery
This trial tests combining a cancer vaccine (V940) with the immunotherapy drug pembrolizumab (Keytruda) for people with non-small cell lung cancer that was treated with chemo and Keytruda before surgery but wasn't completely removed. The goal is to see if adding the vaccine helps prevent the cancer from coming back.
Rockville, MarylandAges 18 years+ - NCT06406465RecruitingPhase 2
Belinostat trial for neuroendocrine cancer based on genetics
This trial tests a drug called belinostat, possibly combined with other drugs, based on your genetic makeup. It aims to find the right dose for people with a rare and aggressive neuroendocrine cancer that started outside the lungs.
Bethesda, MarylandAges 18–120 - NCT05633615RecruitingPhase 2
Testing new drug options after CAR T for aggressive lymphoma
This Phase 2 study tests whether adding or switching drug treatments after CAR T-cell therapy can improve outcomes for people with certain aggressive lymphomas that have come back or did not respond. It mainly looks at who remains disease-stable/partly improved after CAR T and what treatment approach works best next.
Baltimore, MarylandAges 18 years+ - NCT07711002RecruitingPhase 3
Saruparib with standard therapy for metastatic hormone-sensitive prostate cancer
This trial tests a new drug called saruparib, which may help keep prostate cancer from growing. It is for men whose cancer has spread and who have already received certain treatments. The study combines saruparib with a standard hormone therapy to see if it works better than the hormone therapy alone.
Baltimore, MarylandAges 18 years+ - NCT06855277RecruitingPhase 3
AAA817 with hormone therapy for advanced prostate cancer
This trial tests a new combination treatment (AAA817 plus a hormone therapy) against standard care for men with advanced PSMA-positive prostate cancer that has spread and stopped responding to a previous hormone therapy. It may be an option if you haven't had certain prior treatments.
Baltimore, MarylandAges 18–100 - NCT07388563RecruitingPhase 1
Combination drug therapy for returning T-cell lymphoma
This trial tests two drugs, azacitidine and abatacept, given together for T-cell lymphoma that has come back or not improved after earlier treatment. The goal is to see if this combination can control the cancer better, potentially offering a new option for patients.
Bethesda, MarylandAges 18–120 - NCT07665372Recruiting
Liver transplant from donors with HIV for people with HIV
This study tests whether giving people with HIV a liver from an HIV-positive donor is safe and works well. It looks at infections, cancer risks, and long-term health after transplant.
Baltimore, MarylandAges 18 years+ - NCT06426628Recruiting
Nasal swab test for lung nodule risk
This trial tests a new nasal swab test to help doctors better understand your risk if you have a small lung nodule. The test looks at cells from your nose to give more information about whether the nodule might be cancer, without needing a biopsy right away.
Baltimore, MarylandAges 29–85 - NCT07644559RecruitingPhase 2
Study of VS-7375 with cetuximab for advanced pancreatic cancer
This trial tests a new drug combination for people with a specific KRAS mutation in pancreatic cancer. It aims to see if the treatment can shrink tumors or slow the disease.
Baltimore, MarylandAges 18 years+ - NCT03860883Recruiting
Comparing wider versus narrower surgery margins for stage II melanoma
This trial studies whether removing a slightly wider strip of skin around a melanoma improves outcomes compared with a narrower strip. It also uses a lymph node staging procedure to check spread and helps doctors fine-tune surgery for stage II melanoma.
Baltimore, MarylandAges 18 years+ - NCT07514143Recruiting
Bladder Cancer Detection Study Using Urine Test
This study tests a new urine-based test called EpiCheck to help detect bladder cancer. You'll provide urine samples before or during a bladder procedure you're already scheduled to have, and researchers will see how well the test works.
Towson, MarylandAges 22 years+ - NCT07499128Enrolling by invitation
Continuous temperature monitoring for cytokine release syndrome
This study tests a wearable device that continuously monitors your body temperature to detect cytokine release syndrome, a possible side effect of certain immunotherapies. The goal is to catch it early so you can get treatment faster.
Bethesda, MarylandAges 18–120 - NCT07444723RecruitingPhase 2/Phase 3
New imaging to find parathyroid tumors before surgery
This study tests two advanced imaging techniques (PET/MR and PET/CT) to find overactive parathyroid glands or tumors that need surgery. Participants get a special scan before surgery to help surgeons locate the problem more accurately.
Bethesda, MarylandAges 18–100 - NCT07424222RecruitingPhase 1
Ruxolitinib for a serious immune reaction after CAR T therapy
This trial tests a drug called ruxolitinib for a rare but serious condition called IEC-HS that can happen after CAR T cell treatment. The goal is to see if ruxolitinib can calm this overactive immune response.
Baltimore, MarylandAges 18–99 - NCT07412002Recruiting
End-of-life care quality for children with cancer
This trial asks bereaved parents about the quality of care their child received in the last month of life. It aims to improve how hospitals support families when a child with cancer is dying.
Baltimore, MarylandAges 18 years+ - NCT07398209Recruiting
Motion management study for lung cancer patients having radiation
This study uses MRI scans to understand how tumor motion affects radiation therapy planning in lung cancer. It is for patients who are starting radiation treatment, possibly with chemotherapy or immunotherapy.
Baltimore, MarylandAges 18 years+ - NCT07375992Recruiting
Music therapy for newly diagnosed glioblastoma
This trial tests whether attending virtual music therapy sessions can help people with newly diagnosed glioblastoma feel better after chemoradiation. It aims to improve quality of life and emotional well-being.
Baltimore, MarylandAges 18 years+ - NCT02674100Recruiting
Registry for pancreatic cancer patients getting a specific ablation
This is a research registry that collects information from adults with pancreatic cancer who are treated with an ablation procedure called irreversible electroporation (IRE). It may help doctors better understand which patients benefit from this approach and how the treatment is used in real life.
Baltimore, MarylandAges 18 years+ - NCT07337590Recruiting
New device to monitor healing after colorectal cancer surgery
This trial tests a new system that monitors healing inside the body after surgery for colorectal cancer. It is designed to help doctors detect problems early and keep you safe.
Baltimore, MarylandAges 21 years+ - NCT07328503RecruitingPhase 2
CD22 CAR T-cells to prevent relapse after CD19 CAR T-cell therapy
This trial tests if giving a second type of CAR T-cell therapy that targets CD22 can help keep B-cell acute lymphoblastic leukemia (ALL) in remission for people who are already in remission after CD19 CAR T-cell treatment. It aims to reduce the risk of the cancer coming back.
Bethesda, MarylandAges 3–65
Cancer trials by city in Maryland
Where these studies are running in Maryland
Institutions with a site for the recruiting cancer studies listed above.
- National Institutes of Health Clinical Center · 9 studies
- Johns Hopkins University · 6 studies
- University of Maryland/Greenebaum Cancer Center · 2 studies
- Chesapeake Urology Research Associates
- Maryland Oncology Hematology, P.A.
- MedStar Franklin Square Medical Center
- Oncology- Broadway
- Research Site
What taking part in a cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Cancer trials in other states
Common questions
- Are there cancer clinical trials in Maryland?
- Yes. We're currently tracking 707 recruiting cancer studies with a site in Maryland, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cancer study in Maryland?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Maryland to take part?
- Not necessarily. These studies have a site in Maryland, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cancer studies open in Maryland regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.