Clinical trials · Ohio
Cancer clinical trials in Ohio
We’re tracking 794 recruiting cancer studies with a site in Ohio — including Phase 1, Phase 1/Phase 2, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Ohio
- NCT07112196RecruitingPhase 2/Phase 3
Visugromab for cancer-related weight loss
This trial tests a medicine called visugromab for people with advanced cancer who have also lost weight. It aims to help with that weight loss (cachexia) and potentially improve your quality of life.
Avon, OhioAges 18 years+ - NCT07111234Recruiting
Studying flavored nicotine pouches to understand user preferences
This study tests different flavors and cooling agents in oral nicotine pouches to see which ones people prefer. It may help develop safer alternatives for people who currently smoke cigarettes.
Columbus, OhioAges 21 years+ - NCT07099898RecruitingPhase 3
Study of a new drug for relapsed small cell lung cancer
This study tests a new drug (GSK5764227) for people whose extensive-stage small cell lung cancer has gotten worse after platinum chemotherapy combined with immunotherapy. The goal is to see if this targeted treatment can help shrink tumors and control the cancer.
Canton, OhioAges 18 years+ - NCT06914648Recruiting
Liver preparation before surgery study for certain liver cancers
This study tests a procedure called portal vein embolization (PVE) to help grow the healthy part of the liver before surgery. It may be an option for people with certain liver cancers who need more healthy liver tissue before their operation.
Cleveland, OhioAges 18 years+ - NCT07095140Recruiting
Nicotine and flavor effects on alcohol use study
This study tests how different nicotine levels and flavors in oral nicotine products affect alcohol drinking in young adults who use nicotine daily. It could help understand how to reduce alcohol-related harm.
Columbus, OhioAges 21–30 - NCT07082920RecruitingPhase 1
Combination treatment for advanced prostate cancer
This study tests a combination of two new investigational drugs for men with advanced prostate cancer that has spread and is no longer responding to hormone therapy. The drugs aim to help your immune system fight the cancer cells.
Cleveland, OhioAges 18 years+ - NCT07079098RecruitingPhase 1
Quick radiation for limited cancer spread
This trial tests a faster way to give radiation to people with a few spots of cancer that have spread. They use a special scan to plan treatment right away, so you may not need a separate planning visit.
Cleveland, OhioAges 18 years+ - NCT05970497RecruitingPhase 1/Phase 2
KB707 trial for advanced solid tumors after other treatments
This early-stage trial tests KB707 in people with locally advanced or metastatic solid tumors that have not responded well to standard treatments. If you qualify, you may receive KB707 to see how well it can shrink tumors or control the disease.
Canton, OhioAges 18 years+ - NCT07068074RecruitingPhase 3
Comparing less invasive surgery to standard care for older adults with early-stage melanoma
This trial compares less invasive procedures with the current standard treatment for early-stage melanoma in adults 75 and older. The goal is to find out if these less invasive options work just as well and help patients recover better.
Avon, OhioAges 75 years+ - NCT07060807RecruitingPhase 3
Patritumab deruxtecan for advanced breast cancer
This study tests an investigational drug called patritumab deruxtecan for people with a certain type of advanced breast cancer that is hormone receptor-positive and HER2-negative. The drug targets a protein called HER3, which is common on these cancer cells, and may slow or shrink the cancer when previous treatments have stopped working.
Cincinnati, OhioAges 18 years+ - NCT07060261Recruiting
Pre-op MRI for HPV+ tonsil cancer surgery
This trial is looking at whether an MRI before surgery can help improve outcomes for people with HPV-positive tonsil cancer who are undergoing robotic surgery (TORS). The results may help doctors better plan surgery to remove all cancer.
Cleveland, OhioAges 18 years+ - NCT07012044RecruitingPhase 1
Cedazuridine and decitabine after stem cell transplant for childhood leukemia
This trial tests if adding two chemotherapy drugs (cedazuridine and decitabine) along with a growth factor (filgrastim) can help prevent leukemia from coming back after a stem cell transplant. It is for children and young adults with high-risk acute myeloid leukemia who are in remission after transplant.
Cincinnati, OhioAges Up to 21 years - NCT07007273RecruitingPhase 2
Pembrolizumab for advanced skin sarcomas (not angiosarcoma)
This trial is testing a drug called pembrolizumab (Keytruda) for people with advanced soft tissue sarcomas that started in the skin. The goal is to see if this immunotherapy can help shrink or slow the growth of these tumors.
Columbus, OhioAges 18 years+ - NCT07003542RecruitingPhase 2
Sitagliptin for people with high-grade brain tumors
This trial tests whether sitagliptin, a medicine usually used for diabetes, can help people with a fast-growing type of brain tumor (grade 4 glioma). You will take sitagliptin before your planned surgery, and researchers will study how it affects your tumor.
Cleveland, OhioAges 18 years+ - NCT06995677RecruitingPhase 2
Study of TYRA-300 for bladder cancer that has not spread into muscle
This trial tests a new pill, TYRA-300, for people with a certain type of early-stage bladder cancer that has a specific genetic change (FGFR3). The goal is to see if it can help by targeting the cancer cells and possibly avoiding more invasive treatments.
Columbus, OhioAges 18 years+ - NCT06997497RecruitingPhase 3
Study of Calderasib with other drugs for colorectal cancer
This trial tests a new drug called Calderasib combined with targeted therapy or chemotherapy for people with advanced colorectal cancer that has a specific genetic change (KRAS G12C mutation). It may be an option for those who have not had prior treatment for advanced disease.
Centerville, OhioAges 18 years+ - NCT07002034RecruitingPhase 2
RE104 for adjustment disorder related to cancer or other serious illnesses
This trial is testing a new medication (RE104) for people who have adjustment disorder with depressed mood or anxiety because of a serious medical condition like cancer, ALS, MS, Parkinson's, or lung fibrosis. It's a study to see if the drug is safe and reduces symptoms.
Columbus, OhioAges 18–80 - NCT06992427RecruitingPhase 3
Gabapentin to prevent opioid use for mouth pain during cancer treatment
This trial tests if taking gabapentin during chemoradiation for head and neck cancer can reduce the need for strong painkillers like opioids. It may help manage mouth pain caused by treatment.
Canton, OhioAges 18 years+ - NCT06746623Recruiting
Non-endoscopic screening for Barrett's in veterans without reflux
This trial tests a new, non-endoscopic screening method for Barrett's esophagus (a condition that can lead to cancer) in veterans who do not have chronic acid reflux. It aims to find early signs of the condition using a simple swallowable device, potentially avoiding the need for a traditional endoscopy.
Cleveland, OhioAges 40–85 - NCT06975293RecruitingPhase 1/Phase 2
STC-15 with toripalimab for advanced cancers and sarcomas
This trial tests a new drug called STC-15, either alone or with another drug (toripalimab), for people with certain advanced cancers or sarcomas that have progressed after prior treatment. The goal is to see if this combination or single drug can help shrink tumors or slow the disease.
Cleveland, OhioAges 18 years+ - NCT06966700RecruitingPhase 3
Study of Sac-TMT in Early High-Risk Breast Cancer
This study tests a new drug called Sacituzumab Tirumotecan (Sac-TMT) for people with early-stage, high-risk breast cancer that hasn't spread. The drug is given before surgery to see if it can shrink tumors and improve outcomes.
Cincinnati, OhioAges 18 years+ - NCT06971614RecruitingPhase 2
T3011 for bladder cancer not responding to standard treatments
This trial tests a drug called T3011 for a type of bladder cancer that hasn't responded to standard treatments like BCG or chemotherapy. It aims to see if T3011 can help shrink the cancer or keep it from growing, offering a new option for people who have limited choices.
Middleburg Heights, OhioAges 18 years+ - NCT06964737RecruitingPhase 1
CAR T-cell therapy for recurrent brain tumors
This trial tests a new type of immunotherapy called CAR T-cells that target a protein called GARP on your tumor cells. It is for people whose high-grade glioma (a fast-growing brain tumor) has come back after previous treatment.
Columbus, OhioAges 18 years+ - NCT06917911RecruitingPhase 2
Testing two drug additions to standard chemotherapy for a type of acute myeloid leukemia
This trial tests whether adding venetoclax or gemtuzumab ozogamicin to the usual chemotherapy helps people with a specific genetic type of acute myeloid leukemia (AML) respond better. It may improve chances of remission.
Columbus, OhioAges 18–59
Cancer trials by city in Ohio
Where these studies are running in Ohio
Institutions with a site for the recruiting cancer studies listed above.
- The Ohio State University · 7 studies
- Cleveland Clinic · 3 studies
- University Hospitals Cleveland Medical Center · 3 studies
- Cleveland Clinic Main Campus · 2 studies
- Aultman Health Foundation
- Bethesda North Hospital
- Case Western Reserve University
- Cincinnati Children's Hospital Medical Center
What taking part in a cancer study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Cancer trials in other states
Common questions
- Are there cancer clinical trials in Ohio?
- Yes. We're currently tracking 794 recruiting cancer studies with a site in Ohio, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a cancer study in Ohio?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Ohio to take part?
- Not necessarily. These studies have a site in Ohio, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New cancer studies open in Ohio regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.