Clinical trials
Cancer clinical trials
Below are recruiting cancer clinical trials, each written for real people, not researchers. We’re tracking 12,865 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05179408Recruiting
Video rehab after lung cancer treatment for Veterans
This trial tests whether targeted rehab done by video (telerehabilitation) can help Veterans recover after curative (aim-to-cure) lung cancer treatment. It mainly focuses on people who have recently finished surgery or radiation/chemo-radiation and may benefit from guided exercise from home.
Aurora, ColoradoAges 18 years+ - NCT05176483RecruitingPhase 1
New drug combinations for advanced solid tumors
This trial tests a new drug called zanzalintinib, which may slow or shrink various types of advanced cancer. It is given together with other cancer treatments, and the study is looking at many different cancers including kidney, prostate, bladder, lung, liver, and more.
Phoenix, ArizonaAges 18 years+ - NCT04636710Recruiting
Treatment approach study for stage III inflammatory breast cancer
This study looks at how to best plan local treatments (like surgery and/or radiation) for people with stage III inflammatory breast cancer. It may help doctors refine care plans for this aggressive subtype by studying how patients are treated and what outcomes they have.
Boston, MassachusettsAges 18 years+ - NCT05129969Recruiting
Registry for advanced ovarian or endometrial cancer patients
This registry collects information from people with advanced ovarian or endometrial cancer to better understand care and outcomes. It may help researchers and doctors learn which treatments work best for different patients.
Multiple LocationsAges 18 years+ - NCT05103683RecruitingPhase 1
First-time test of TORL-1-23 for advanced solid tumors
This early study tests a new drug (TORL-1-23) in people with advanced solid cancers. It aims to find the safest dose and see how the tumor responds.
Fullerton, CaliforniaAges 18 years+ - NCT05098132RecruitingPhase 1/Phase 2
STK-012 drug for advanced lung cancer and other tumors
This trial tests STK-012 (alone and with other treatments) in people with advanced cancers, especially non-small cell lung cancer. It may help by activating the immune system to recognize and fight the tumor.
Tucson, ArizonaAges 18 years+ - NCT05123807RecruitingPhase 2
Surgery plus heated chemotherapy for recurrent mucinous ovarian cancer
This trial studies a planned surgery to remove as much cancer as possible, followed by heated chemotherapy placed in the belly (called HIPEC). It’s for people with recurrent mucinous ovarian cancer, aiming to control the cancer and improve outcomes.
Houston, TexasAges 18 years+ - NCT05130801RecruitingPhase 1/Phase 2
MRI and pHLIP dye during breast surgery to map tumors
This trial tests whether a special MRI and an injected light-activated dye (pHLIP® ICG) can help doctors see and target breast cancer during surgery. You may be offered this approach around the time of breast-conserving surgery, to improve how well the tumor area is identified.
Montvale, New JerseyAges 18 years+ - NCT05132244Recruiting
Monitoring blood sugar levels in people starting pancreatic cancer treatment
This study looks at how well blood sugar (glucose) levels can be monitored and managed in people with pancreatic cancer who are starting their first treatment. It aims to understand if careful glucose management can improve well-being and possibly treatment outcomes.
Vancouver, British ColumbiaAges 18 years+ - NCT05126472RecruitingPhase 1/Phase 2
Study of 2141-V11 for bladder cancer that did not respond to standard treatment
This trial tests a new drug, 2141-V11, for people with bladder cancer that has not gone away after standard treatments like BCG therapy. It may help those with non-muscle invasive bladder cancer or, in one group, muscle-invasive bladder cancer, who cannot have or choose not to have bladder removal surgery.
Basking Ridge, New JerseyAges 18 years+ - NCT05065801RecruitingPhase 2
New metastatic pancreatic cancer: targeted chemo before FOLFIRINOX
This trial tests whether adding Gembrax (a combination that includes gemcitabine and nab-paclitaxel) before standard FOLFIRINOX works better than FOLFIRINOX alone in people with pancreatic cancer that has already spread. It looks at whether this “step-up first” approach improves results and is still tolerable.
Grenoble, Auvergne-Rhône-AlpesAges 18–75 - NCT05029999RecruitingPhase 1
Test drugs for HER2-negative advanced breast cancer
This Phase 1 trial tests a combination of immune-targeting drugs (a CD40 medicine and a substance that helps immune cells act) plus chemotherapy in people with HER2-negative advanced breast cancer that has progressed. It aims to find a safer dose and see whether the treatment can shrink tumors or slow the cancer.
Chicago, IllinoisAges 18–99 - NCT05006131Recruiting
Pancreatic cancer screening for people at higher risk
This study looks at how to screen the pancreas in people who are at increased risk for pancreatic cancer, using a set of risk guidelines. Screening may help find cancer (or early changes) sooner, when it may be easier to treat.
Boston, MassachusettsAges 18–90 - NCT05042687Recruiting
Compare a breast imaging scan with MRI in high-risk women
This study compares two ways of imaging the breast—molecular breast imaging (a scan that uses a small radioactive tracer) and standard breast MRI—to better find or rule out breast cancer. You may join if you are considered high risk and already have a breast MRI planned, and you can do both tests close together.
Houston, TexasAges 18 years+ - NCT05053867RecruitingPhase 3
Inhaled drug to treat lung bleeding in ventilated cancer patients
This Phase 3 study tests whether inhaled tranexamic acid can reduce lung bleeding (pulmonary hemorrhage) in people with cancer who are on a breathing machine. If you qualify, you may receive the study drug to help stop bleeding in the lungs.
Houston, TexasAges 18 years+ - NCT05035836RecruitingPhase 2
Test drug after early HER2-positive breast cancer surgery
This trial tests zanidatamab, a type of targeted antibody treatment, in people with early-stage HER2-positive breast cancer to see how well it works and how safe it is. Because it’s a single-arm pilot study, everyone in the study gets the drug, and you’ll likely be asked to undergo standard surgery if appropriate.
Houston, TexasAges 18 years+ - NCT05004116RecruitingPhase 1/Phase 2
Repotrectinib plus chemotherapy for relapsed solid tumors in youth
This early-phase study tests repotrectinib (a targeted anti-cancer pill) combined with chemotherapy in children and young adults whose solid tumors have come back or did not respond to standard treatment. The goal is to see how safe the treatment is and whether it can shrink tumors.
New York, New YorkAges 1–25 - NCT04969315RecruitingPhase 1/Phase 2
Study of two new drugs for advanced kidney, prostate, lung, or mesothelioma cancer
This study tests two new study drugs (TT-4 and TT-10) alone and together in people with certain advanced cancers that have not responded to standard treatments. The goal is to see if these drugs are safe and effective in shrinking tumors or slowing the cancer's growth.
Los Angeles, CaliforniaAges 18 years+ - NCT04977453RecruitingPhase 1/Phase 2
Study drug GI-101 alone or with immune or blood-pressure meds
This early-phase study tests GI-101 in people with advanced solid cancers. It may be given alone or combined with pembrolizumab or lenvatinib to see how safe it is and whether it can shrink tumors.
New York, New YorkAges 18 years+ - NCT04930432RecruitingPhase 1/Phase 2
MCLA-129 for advanced EGFR- and MET-positive lung and other cancers
This early-phase trial tests MCLA-129, an antibody that targets EGFR and MET, in people with advanced cancers that have specific lab “biomarker” results. It’s for patients whose cancer has grown after standard treatments or can’t take standard treatment, with the goal of shrinking tumors and improving symptoms.
BaodingAges 18 years+ - NCT04947098Recruiting
Preventing cancer in adults
This trial looks at ways to help prevent cancer in adults. It may be helpful if you’re interested in cancer prevention and meet the basic age requirements.
Greenville, South CarolinaAges 18 years+ - NCT04995198Recruiting
Prostate cancer patient registry for genetics and treatment outcomes
This registry collects information from people with prostate cancer to better understand how genetics and treatments affect survival and outcomes. Your data may help researchers improve future treatment choices.
Baltimore, MarylandAges 18 years+ - NCT04996316Enrolling by invitation
Breast cancer screening decision help for women 40–74
This trial tests a breast cancer screening risk and decision aid to help you and your clinician choose the right next steps for screening and referrals. You may benefit by getting clearer, personalized guidance based on your risk.
Portland, OregonAges 40–74 - NCT04968964Recruiting
Monitoring test for CDK4/6 drugs in metastatic breast cancer
This study follows people with hormone receptor–positive, HER2-negative metastatic breast cancer who are taking CDK4/6 inhibitor treatment (with or without an added blood test called DiviTum®). The goal is to see how well the standard treatment is working and whether DiviTum® (a serum TK1 activity test) can help guide monitoring.
St Louis, MissouriAges 18 years+
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Common questions
- Are there clinical trials for cancer?
- Yes. Clin2 currently lists 12,865 recruiting cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.