Clinical trials
Cancer clinical trials
Below are recruiting cancer clinical trials, each written for real people, not researchers. We’re tracking 13,110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05913674RecruitingPhase 2
Feasibility of modified chemotherapy after bowel surgery
This Phase 2 study tests whether a modified chemotherapy given inside the abdomen soon after surgery is practical and safe. It may help people with appendix or colon cancer that has spread within the abdomen (peritoneal carcinomatosis) by targeting cancer cells after tumor removal.
Montreal, QuebecAges 18 years+ - NCT05914389RecruitingPhase 2
Immunotherapy plus chemotherapy before surgery for colon cancer
This Phase 2 trial studies giving chemotherapy plus immune therapy before surgery for certain colon cancers that do not have mismatch repair defects (MSS/pMMR). The goal is to shrink and control the tumor and improve outcomes compared with standard approaches.
Hangzhou, ZhejiangAges 18–75 - NCT05917301Recruiting
Pre-surgery proton radiation for soft tissue sarcoma
This trial studies a shorter-course proton radiation plan given before surgery for certain soft tissue sarcomas. The goal is to treat the tumor locally while helping surgery be safer or more effective.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05918094RecruitingPhase 3
Testing new chemo plan plus immunotherapy for stomach cancer
This phase 3 study compares two versions of a first-time treatment for HER2-negative advanced stomach or gastroesophageal cancer, both including immunotherapy (sintilimab). It looks for a safer or more effective way to slow cancer growth or improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT05918510Recruiting
Blood and tumor study for virus markers in throat cancer
This study looks at virus-related markers and tiny gene regulators (microRNAs) in tumor tissue from people with certain throat cancers caused by human papilloma virus (HPV). It’s observational, meaning it does not change your treatment, but results may help doctors better understand these cancers and how they behave.
RomeAges 18 years+ - NCT05919758Recruiting
Looking at surgery for high-risk appendix tumors in children
This trial studies outcomes after removing the right side of the colon (right-sided hemicolectomy) in children who had a high-risk neuroendocrine tumor of the appendix. It aims to understand whether this more extensive surgery is valuable compared with other approaches.
Amsterdam-ZuidoostAges Up to 17 years - NCT05920798RecruitingPhase 1/Phase 2
Vaccine treatment plus pembrolizumab for recurrent ovarian cancer
This Phase 1/2 trial tests a new cancer vaccine therapy combined with pembrolizumab (an immunotherapy) to treat advanced, recurrent ovarian, fallopian tube, or primary peritoneal cancer. It may help your immune system recognize and attack the cancer, especially if your tumor has a specific target called FRα.
Scottsdale, ArizonaAges 18 years+ - NCT05920863RecruitingPhase 2
Lenvatinib, immunotherapy, plus liver artery treatment before surgery
This Phase 2 trial tests whether giving lenvatinib and immunotherapy along with TACE (a liver artery treatment) before surgery can lower the risk of hepatocellular carcinoma coming back after surgery. It targets people with certain higher-risk early-stage liver tumors (CNLC IB/IIA).
Hangzhou, ZhejiangAges 18–75 - NCT05921253RecruitingEarly Phase 1
Check a brain-heart device to reduce chemo heart risk
This early-phase study tests a “neuromodulation” device (stimulating nerves that may affect the heart and blood vessels) to help lower cardiovascular risks after certain cancer chemotherapy. It may be most relevant if you recently had an anthracycline-based treatment and also have other heart-risk factors.
Oklahoma City, OklahomaAges 18–99 - NCT05922761RecruitingPhase 2
Belumosudil for lung scar prevention or treatment after transplant
This Phase 2 study tests belumosudil to treat or prevent bronchiolitis obliterans (BOS), a lung complication that can happen after a stem cell transplant. If you qualify, you would be checked closely with breathing tests and scans, and watched for safety and whether lung function improves or stays stable.
Stanford, CaliforniaAges 18 years+ - NCT05922501RecruitingPhase 2
Test four medicines for relapsed multiple myeloma
This Phase 2 study tests a combination of medicines (isatuximab, belantamab mafodotin, pomalidomide, and dexamethasone) for multiple myeloma that has come back or did not respond to prior treatment. It may help by better controlling the myeloma after standard therapies have failed.
Boston, MassachusettsAges 18 years+ - NCT05927142RecruitingPhase 1/Phase 2
Durvalumab plus rintatolimod for metastatic pancreatic cancer
This early-phase study tests whether adding rintatolimod to durvalumab can improve outcomes for people with metastatic pancreatic cancer. It aims to see if this combination can better activate the immune system against the cancer after initial chemotherapy.
Rotterdam, South HollandAges 18 years+ - NCT05929612RecruitingPhase 2
Low-dose targeted radiation alone for marginal zone lymphoma
This Phase 2 study tests whether very low-dose radiation (adjusted based on how you respond) can treat marginal zone lymphoma without adding other medicines at first. It may help some people by reducing radiation exposure while still controlling the cancer.
Houston, TexasAges 18 years+ - NCT05929976Recruiting
Study of gut and blood chemistry in children with new leukemia
This study looks at the gut microbiome (tiny organisms in the gut) and metabolome (small chemicals in the body) in children and teens with newly diagnosed ALL. It may help researchers understand what is happening in the body early in treatment and could guide future, more personalized care.
New York, New YorkAges 3–18 - NCT05930860Recruiting
Endoscopic treatment for certain superficial stomach growths
This trial studies how safe and effective a procedure called endoscopic submucosal dissection (ESD) is for treating certain early, superficial stomach (gastric) growths. It may be an option if your growth fits the endoscopy criteria and you are not a good candidate for stomach surgery.
RomeAges 18 years+ - NCT05931068Recruiting
Measuring energy use during major liver surgery
This study looks at how much energy your body uses during major liver surgery by measuring breathing and metabolism. It may help doctors better plan care around surgery and understand how your body responds.
MaastrichtAges 18 years+ - NCT05932680RecruitingPhase 2
Continue teclistamab for a limited time in responding patients
This Phase 2 trial looks at stopping or limiting teclistamab after you’ve already had a good ongoing response. It aims to see if people can safely continue to benefit while using the medicine for a shorter time.
Little Rock, ArkansasAges 18 years+ - NCT05933122Recruiting
Sexual health support after rectal cancer surgery
This study looks at how common sexual difficulties are in women after rectal cancer surgery, and whether a sexologist-led support program can help. If you qualify, you may be asked about sexual well-being and take part in counseling support.
Brive-la-GaillardeAges 18 years+ - NCT05934032Recruiting
Genomic medicine for non-surgical lung cancer
This trial is part of a lung cancer network that uses genetic (DNA) testing to better understand and treat non-surgical lung cancer. You might be eligible if you have certain stages of non-small cell lung cancer and can consent to participate.
CologneAges 18 years+ - NCT05936034Recruiting
Hearing aid vs no hearing aid during platinum chemotherapy
This study compares how patients’ quality of life changes when people who have hearing loss from platinum chemotherapy use a hearing aid versus not using one. It may help understand whether hearing aids improve daily life during treatment.
Vandœuvre-lès-NancyAges 18 years+ - NCT05936736Recruiting
One-time radiation for prostate cancer with bladder-sparing approach
This trial tests whether giving prostate radiation in one treatment session can work well while protecting the bladder. It may help certain people with localized prostate cancer by aiming for good cancer control with fewer bladder/urinary side effects.
Milan, MIAges 18 years+ - NCT05938192Recruiting
Treatments for HPV-related genital tract changes
This trial studies treatment approaches for conditions caused by human papillomavirus (HPV) in the female genital tract. It may help people whose HPV-related disease is being evaluated for new or combined treatment options.
Milan, LombardyAges 18 years+ - NCT05940272Recruiting
Communication training for doctors treating large B-cell lymphoma
This study tests a communication training program for providers who care for people with large B-cell lymphoma. The goal is to improve how clinicians talk with patients, especially during difficult treatment periods like relapse.
New York, New YorkAges 18 years+ - NCT05940311Recruiting
Blood test for melanoma with BRAF V600E mutation
This trial studies a very sensitive blood test to detect melanoma-related genetic changes in people with BRAF V600E. It may help track the disease more closely and guide care in advanced or high-risk situations.
RomeAges 18 years+
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Common questions
- Are there clinical trials for cancer?
- Yes. Clin2 currently lists 13,110 recruiting cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.