Clinical trials
Cancer clinical trials
Below are recruiting cancer clinical trials, each written for real people, not researchers. We’re tracking 13,110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04993014RecruitingPhase 2
De-escalating treatment after HER2-positive breast cancer responds
This study looks at whether some people with HER2-positive breast cancer can safely receive less (de-escalated) treatment after they finish chemotherapy plus HER2-targeted drugs before surgery. It specifically focuses on people whose cancer shows a complete response on the surgery pathology report.
São PauloAges 18 years+ - NCT04995198Recruiting
Prostate cancer patient registry for genetics and treatment outcomes
This registry collects information from people with prostate cancer to better understand how genetics and treatments affect survival and outcomes. Your data may help researchers improve future treatment choices.
Baltimore, MarylandAges 18 years+ - NCT05004116RecruitingPhase 1/Phase 2
Repotrectinib plus chemotherapy for relapsed solid tumors in youth
This early-phase study tests repotrectinib (a targeted anti-cancer pill) combined with chemotherapy in children and young adults whose solid tumors have come back or did not respond to standard treatment. The goal is to see how safe the treatment is and whether it can shrink tumors.
New York, New YorkAges 1–25 - NCT05024929Recruiting
Test targeted drugs to help radioactive iodine reach thyroid cancer
This study looks at whether certain cancer “targeted therapy” medicines can make radioactive iodine (RAI) therapy work better for thyroid cancer that has spread to the lungs. It also involves taking special whole-body scans to measure how much radioactive iodine gets taken up by the cancer.
San Francisco, CaliforniaAges birth+ - NCT05025878Recruiting
Study tracking sugar and immune cells in ovarian cancer fluid
This study uses a trace amount of glucose (a type of sugar) to see how tumor cells and immune cells behave inside the fluid that collects with ovarian cancer (ascites). It may help researchers understand what drives cancer activity and immune responses, which could guide better treatments in the future.
Victoria, British ColumbiaAges 18 years+ - NCT05029999RecruitingPhase 1
Test drugs for HER2-negative advanced breast cancer
This Phase 1 trial tests a combination of immune-targeting drugs (a CD40 medicine and a substance that helps immune cells act) plus chemotherapy in people with HER2-negative advanced breast cancer that has progressed. It aims to find a safer dose and see whether the treatment can shrink tumors or slow the cancer.
Chicago, IllinoisAges 18–99 - NCT05035147RecruitingPhase 4
Albumin-bound paclitaxel plus gemcitabine for advanced pancreatic cancer
This trial studies a chemotherapy combination (albumin-bound paclitaxel and gemcitabine) as first treatment for pancreatic cancer that cannot be removed by surgery. It aims to improve outcomes by testing how well this treatment works in people with locally advanced or metastatic disease.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05035745RecruitingPhase 1/Phase 2
Selinexor plus talazoparib for advanced triple-negative breast cancer
This trial tests selinexor plus talazoparib in people with advanced, treatment-resistant solid tumors and, separately, advanced triple-negative breast cancer. It aims to see whether this combination can shrink tumors or slow their growth when standard options have not worked.
SingaporeAges 18–99 - NCT05035836RecruitingPhase 2
Test drug after early HER2-positive breast cancer surgery
This trial tests zanidatamab, a type of targeted antibody treatment, in people with early-stage HER2-positive breast cancer to see how well it works and how safe it is. Because it’s a single-arm pilot study, everyone in the study gets the drug, and you’ll likely be asked to undergo standard surgery if appropriate.
Houston, TexasAges 18 years+ - NCT05042687Recruiting
Compare a breast imaging scan with MRI in high-risk women
This study compares two ways of imaging the breast—molecular breast imaging (a scan that uses a small radioactive tracer) and standard breast MRI—to better find or rule out breast cancer. You may join if you are considered high risk and already have a breast MRI planned, and you can do both tests close together.
Houston, TexasAges 18 years+ - NCT05044689Recruiting
Study to find risk factors for breast and colon cancer
This study is trying to understand what factors might raise the risk of breast cancer and colon (large bowel) cancer. You may be enrolled either if you have a confirmed cancer diagnosis (cases) or if you do not have cancer (controls).
Ile-Ife, Osun StateAges Any age - NCT05053867RecruitingPhase 3
Inhaled drug to treat lung bleeding in ventilated cancer patients
This Phase 3 study tests whether inhaled tranexamic acid can reduce lung bleeding (pulmonary hemorrhage) in people with cancer who are on a breathing machine. If you qualify, you may receive the study drug to help stop bleeding in the lungs.
Houston, TexasAges 18 years+ - NCT05055635RecruitingPhase 2
Proton radiation for anal cancer that came back after prior treatment
This trial studies a focused type of proton radiation (“pencil beam”) to treat anal cancer that has returned after you previously had radiation. It may help by aiming treatment more precisely and giving another chance at cure when doctors think it can still be treated.
Aarhus N, AarhusAges 18 years+ - NCT05056350Recruiting
Coaching to help you return to work after breast cancer
This study tests whether a tailored coaching program can help people with non-metastatic breast cancer return to work in a way that fits their physical and emotional needs. It’s for people who have finished most cancer treatments and are dealing with job-related difficulties.
MontpellierAges 18 years+ - NCT05063136RecruitingPhase 3
Metronomic capecitabine with hormone therapy after breast cancer
This trial studies whether a low-dose “metronomic” chemotherapy medicine (capecitabine) added to standard hormone therapy can reduce breast cancer coming back. It is for people with hormone-receptor–positive, HER2-negative breast cancer after surgery and chemo.
Zhengzhou, HenanAges 18–70 - NCT05065801RecruitingPhase 2
New metastatic pancreatic cancer: targeted chemo before FOLFIRINOX
This trial tests whether adding Gembrax (a combination that includes gemcitabine and nab-paclitaxel) before standard FOLFIRINOX works better than FOLFIRINOX alone in people with pancreatic cancer that has already spread. It looks at whether this “step-up first” approach improves results and is still tolerable.
Grenoble, Auvergne-Rhône-AlpesAges 18–75 - NCT05072600RecruitingPhase 2
Pembrolizumab after complete bladder cancer treatment response
This trial studies pembrolizumab (an immunotherapy) in people with muscle-invasive bladder cancer who had a combined “trimodality” treatment and then achieved a complete response. The goal is to help control the cancer after the initial treatment is finished.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05086614RecruitingPhase 3
Thymosin-alpha 1 after surgery for high-risk colon cancer
This trial looks at whether thymosin-alpha 1, an immune-support treatment, can help prevent colon cancer from coming back after surgery. It targets people with high-risk stage II or III colon cancer who have had the tumor removed.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT05097274Recruiting
PET-CT scan for men with prostate cancer and a DNA repair mutation
This study uses a special scan (FCH-PET-CT) to help doctors see prostate cancer more clearly in men who have a known gene change involved in DNA repair. It’s meant to improve staging and assessment, especially around when imaging is needed.
London, Sutton, SurreyAges 18 years+ - NCT05103683RecruitingPhase 1
First-time test of TORL-1-23 for advanced solid tumors
This early study tests a new drug (TORL-1-23) in people with advanced solid cancers. It aims to find the safest dose and see how the tumor responds.
Fullerton, CaliforniaAges 18 years+ - NCT05104788RecruitingPhase 2
Icotinib plus chemotherapy before surgery for EGFR lung cancer
This trial studies how well a targeted medicine (icotinib) combined with chemotherapy works before surgery for certain EGFR-mutated lung adenocarcinoma. The goal is to shrink or control the tumor and make surgery more effective.
BeijingAges 18–75 - NCT05109910Recruiting
Checking lymph node surgery impact in men having prostate removal
This study looks at whether removing lymph nodes during prostate removal helps predict outcomes in men whose scans do not show spread. It may help improve how doctors decide who benefits from lymph node surgery based on your risk level and scan results.
AmsterdamAges 18 years+ - NCT05112016Recruiting
Study of surgery outcomes after rectal cancer
This study follows people who had surgery for rectal cancer to understand long-term recovery and quality of life. You may be asked to complete questionnaires before surgery and again after the stoma is reversed, and your answers help researchers improve care.
Winterthur, Canton of ZurichAges 18 years+ - NCT05113368RecruitingPhase 2
Regorafenib plus fulvestrant for recurrent low-grade ovarian cancer
This trial tests whether regorafenib (a targeted pill) plus fulvestrant (an injection that lowers estrogen signaling) can slow down recurrent low-grade serous ovarian cancer. It may help people whose cancer has returned after prior treatments.
Cleveland, OhioAges 18 years+
Hear when a new Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cancer?
- Yes. Clin2 currently lists 13,110 recruiting cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.