Clinical trials · California
Carcinoma clinical trials in California
We’re tracking 469 recruiting carcinoma studies with a site in California — including Early Phase 1, Phase 1, Phase 1/Phase 2, Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in California
- NCT03909282Recruiting
Surgery now versus radiation then delayed surgery for DCIS
This trial compares two approaches for ductal carcinoma in situ (DCIS): having surgery first versus getting radiation first and then having surgery later. It aims to see which plan controls DCIS better while affecting treatment timing and outcomes.
Stanford, CaliforniaAges 18 years+ - NCT03606967RecruitingPhase 2
Individualized vaccine added to standard treatment for metastatic triple-negative breast cancer
This Phase 2 trial tests whether adding a personalized cancer vaccine to durvalumab (an immunotherapy), tremelimumab (another immunotherapy), and chemotherapy can improve outcomes for people with metastatic triple-negative breast cancer. It may help your immune system recognize your specific tumor features.
Orange, CaliforniaAges 18 years+ - NCT03191149RecruitingPhase 2
Osimertinib for lung cancer with an EGFR exon 20 change
This Phase 2 study tests osimertinib (a targeted lung cancer pill) in people with advanced non-small cell lung cancer (NSCLC) whose tumors have an EGFR exon 20 insertion. It aims to see how well osimertinib works for this specific EGFR mutation and how safe it is.
Burbank, CaliforniaAges 18 years+ - NCT01385722Enrolling by invitation
Molecular testing for cancers in the chest
This study looks at the genetic changes (molecular analysis) in certain cancers of the chest. It may help doctors learn more about what drives these cancers and how they might be diagnosed or treated in the future.
Stanford, CaliforniaAges 18 years+ - NCT00477100Recruiting
Breast cancer tissue and data registry for research
This trial helps create a research “tissue registry” by collecting breast cancer tissue samples and medical information. It may help doctors better understand inflammatory or invasive breast cancer and improve future studies.
La Jolla, CaliforniaAges 18 years+ - NCT06465069RecruitingPhase 1
Study of an experimental drug for advanced bladder and other cancers
This trial tests a new drug called LY4052031 for people with advanced or metastatic cancers, especially bladder cancer. The drug aims to slow or stop tumor growth. Doctors will check if it is safe and how well it works.
Duarte, CaliforniaAges 18 years+ - NCT05229341Recruiting
Testing DNA “methylation” to evaluate thyroid nodule samples
This study looks at patient tissue from needle biopsies to see if DNA “methylation” patterns can help diagnose and guide treatment for thyroid nodules. You might benefit by helping improve how these nodules are evaluated, using information from your biopsy sample and medical data.
Duarte, CaliforniaAges 18 years+ - NCT07288034RecruitingPhase 2
Immunotherapy biomarkers for advanced lung cancer
This study looks at blood and tissue biomarkers to predict how well immunotherapy (with or without chemotherapy) works for advanced non-small cell lung cancer. It also helps decide the best second treatment if the first one stops working.
Corona, CaliforniaAges 18 years+ - NCT06623422RecruitingPhase 3
Vaccine plus Keytruda for lung cancer after surgery
This trial tests combining a cancer vaccine (V940) with the immunotherapy drug pembrolizumab (Keytruda) for people with non-small cell lung cancer that was treated with chemo and Keytruda before surgery but wasn't completely removed. The goal is to see if adding the vaccine helps prevent the cancer from coming back.
Fullerton, CaliforniaAges 18 years+ - NCT07388524RecruitingPhase 3
Testing atezolizumab after surgery for early stage lung cancer
This trial tests if the immunotherapy drug atezolizumab can prevent early stage non-small cell lung cancer from coming back after surgery. It is for people whose tumors have high levels of a protein called PD-L1 (50% or more) and do not have certain gene changes (EGFR or ALK).
Beverly Hills, CaliforniaAges 18 years+ - NCT06827236RecruitingPhase 1/Phase 2
Testing a new combination treatment for advanced breast cancer
This study tests two experimental drugs, BNT323 and BNT327, together in people with advanced breast cancer. The goal is to find the best dose and see if the combination is safe and helpful.
Beverly Hills, CaliforniaAges 18 years+ - NCT05851365RecruitingEarly Phase 1
MRI scan to measure prostate acidity before surgery
This study tests a new MRI technique that measures acidity in prostate tumors. It may help doctors better understand the cancer before surgery, potentially guiding treatment decisions.
San Francisco, CaliforniaAges 18 years+ - NCT06084416RecruitingPhase 1
Pill study for advanced ovarian cancer that resists chemo
This trial tests an experimental drug called sovilnesib (taken as a pill) for people with advanced ovarian, fallopian tube, or peritoneal cancer that has stopped responding to platinum chemo. The goal is to see if this drug can shrink or slow the cancer.
Newport Beach, CaliforniaAges 18 years+ - NCT04282044RecruitingPhase 1
CRX100 drug trial for advanced cancers with or without pembrolizumab
This Phase 1 trial tests CRX100 (a new cancer medicine) alone and with pembrolizumab (an immune checkpoint drug) in people with advanced solid tumors. It’s mainly designed to check safety and side effects, and to see whether tumors respond, potentially helping people whose cancer has come back or stopped responding to standard treatment.
Stanford, CaliforniaAges 18 years+ - NCT04603209Recruiting
Check-in registry for radiation during breast-conserving surgery
This registry study tracks people with early-stage, single-area breast cancer to understand outcomes when radiation is given during breast-conserving surgery. It may help doctors improve treatment planning for patients like you.
Santa Monica, CaliforniaAges 18 years+ - NCT07720284RecruitingPhase 3
Testing new drugs for high-risk bladder cancer after surgery
This trial tests a new combination of drugs (Dato-DXd plus rilvegostomig) against standard treatments for people with high-risk, muscle-invasive bladder cancer that has been surgically removed. The goal is to see if the new treatment reduces the chance of the cancer coming back.
San Francisco, CaliforniaAges 18 years+ - NCT07690852Recruiting
Environmental exposures and breast cancer risk study
This study looks at how environmental exposures might affect breast cancer risk. It includes women at average risk, high risk, or those diagnosed with breast cancer before age 50, as well as healthcare providers.
Duarte, CaliforniaAges 18 years+ - NCT07673016Recruiting
Collecting urine to test a new bladder cancer detection method
This study collects urine samples to test UroAmp, a new genetic test that may help detect and monitor bladder cancer. It is for people with bladder cancer or blood in urine who want to help improve cancer detection.
Oceanside, CaliforniaAges 18 years+ - NCT07664397RecruitingPhase 1
Imaging study of a new tracer for cancer detection
This study tests a new imaging tracer called [89Zr]DFO-YS5 that may help detect certain cancers on a PET-CT scan. The goal is to see if this tracer is safe and works well for finding tumors, which could one day help doctors plan better treatments.
San Francisco, CaliforniaAges 18 years+ - NCT07625644RecruitingPhase 3
New immunotherapy combination for advanced lung cancer
This trial tests a new drug called BL-M14D1 combined with atezolizumab (an immunotherapy) against standard chemotherapy for extensive-stage small cell lung cancer, a serious type of lung cancer that has spread. The goal is to see if this combination helps patients live longer and control their cancer better.
Glendale, CaliforniaAges 18 years+ - NCT07586202RecruitingPhase 2
Testing New Drug Combinations Before Lung Cancer Surgery
This trial tests whether giving new drugs (amivantamab plus either lazertinib or chemotherapy) before surgery helps people with a specific type of lung cancer that can be removed. The goal is to shrink tumors and improve surgery outcomes.
Irvine, CaliforniaAges 18 years+ - NCT07544589RecruitingPhase 1
Study of DISP-10 for advanced gastrointestinal cancers
This trial tests a new treatment called DISP-10 for people with advanced cancers of the digestive system, such as stomach, colon, or bile duct cancers. It aims to see if DISP-10 is safe and effective.
Duarte, CaliforniaAges 18 years+ - NCT07546331Recruiting
Body Composition and Breast Reconstruction Outcomes
This study measures body composition (muscle and fat distribution) in patients undergoing breast reconstruction after mastectomy to understand how these measurements relate to surgical outcomes and recovery. Understanding these connections may help doctors better predict and optimize results for future patients.
San Francisco, CaliforniaAges 18 years+ - NCT07512271Recruiting
AI Education Tool for Breast Cancer Patients
This study tests a new computer-based education module created by artificial intelligence to help breast cancer patients understand their diagnosis and treatment options. The goal is to see if this tool helps patients feel more informed and prepared for their care.
San Francisco, CaliforniaAges 18 years+
Carcinoma trials by city in California
Where these studies are running in California
Institutions with a site for the recruiting carcinoma studies listed above.
- City of Hope · 6 studies
- University of California, San Francisco · 4 studies
- Hoag Memorial Hospital Presbyterian · 3 studies
- Stanford University · 2 studies
- Beverly Hills Cancer Center
- Cedars-Sinai Cancer - Tarzana
- Cedars-Sinai Medical Center
- City of Hope 1
What taking part in a carcinoma study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Carcinoma trials in other states
Common questions
- Are there carcinoma clinical trials in California?
- Yes. We're currently tracking 469 recruiting carcinoma studies with a site in California, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a carcinoma study in California?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in California to take part?
- Not necessarily. These studies have a site in California, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a carcinoma trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New carcinoma studies open in California regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.