Clinical trials
Cardiometabolic Health clinical trials
Below are recruiting cardiometabolic health clinical trials, each written for real people, not researchers. We’re tracking 81 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07740291Recruiting
Tirzepatide and lifestyle study for weight loss
This trial compares two ways to manage weight: taking a GLP-1 medication (like tirzepatide or semaglutide) versus making lifestyle changes without medication. It will help researchers learn which approach works best for people with overweight or obesity.
Lubbock, TexasAges 18 years+ - NCT07247487Recruiting
Diet and Heart Health in Rosario
This study looks at how different diets (vegan, vegetarian, or omnivorous) affect heart health and metabolism in Rosario. It's a good fit if you're a generally healthy adult who has been following one of these diets for at least a year.
Rosario, Santa Fe ProvinceAges 18–65 - NCT05606432Recruiting
Movement-to-music exercise program for people with mobility limits
This study tests whether a movement-to-music exercise program at home can improve cardiometabolic health (health related to heart and blood sugar) for adults who use a wheelchair and are not already exercising regularly. You may benefit if you can exercise using your arms and can do moderate activity safely.
Birmingham, AlabamaAges 18–89 - NCT05321368Recruiting
Program to help control blood pressure and support health equity
This study tests a program that combines clinic care, community support, and phone-based monitoring to help people better manage blood pressure and related health problems. It aims to reduce health differences between groups that have been affected more by preventable disease.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06336525Enrolling by invitation
Sleep health in rural Appalachia and Mississippi Delta
This study examines how sleep is linked to heart and metabolic health in people living in rural Appalachia and the Mississippi Delta. If you are already part of the RURAL Study, you may be able to join this sleep-focused part of the research.
Boston, MassachusettsAges 25–65 - NCT06907862Recruiting
SWITCH trial: swapping processed soy foods in a heart-healthy diet
This study tests whether swapping highly processed soy foods for less processed soy foods, as part of a heart-healthy diet, can improve blood pressure, blood sugar, and weight in adults with obesity and high blood pressure. It may be a good option if you have type 2 diabetes and are already on stable medications.
Toronto, OntarioAges 18 years+ - NCT07202247RecruitingPhase 2
Improving heart health in prostate cancer patients on hormone therapy
This study tests whether combining a time-restricted eating plan, a heart-healthy diet, and a weight-loss medication (GLP-1 receptor agonist) can help improve heart health and weight in men with prostate cancer who are receiving hormone therapy. It aims to reduce the risk of heart problems caused by hormone treatment.
Duarte, CaliforniaAges 30–79 - NCT07325500RecruitingPhase 2
Low dose GLP-1 for heart health in HIV
This study tests a very low dose of a medication called a GLP-1 receptor agonist to see if it can improve heart and metabolic health in people with HIV who have excess weight.
Houston, TexasAges 18 years+ - NCT03957928Recruiting
Mango pulp study for hunger and heart-health markers
This study tests whether eating fresh mango pulp can make you feel fuller (less hungry) and improve “heart-health” measurements. It may help people who are interested in diet changes, especially those with higher body weight and related health risks.
San Diego, CaliforniaAges 18–55 - NCT06433115Recruiting
Lean beef and your heart and gut health trial
This study tests how eating lean beef for 4 weeks affects your heart health and the bacteria in your gut. If you qualify, you'll be asked to follow a consistent diet and activity routine during the study.
Columbia, MissouriAges 18–45 - NCT07406412Recruiting
Hormones and heart health before and after ovary removal
This study looks at how hormones affect heart health and metabolism in women who are having their ovaries removed (for non-cancer reasons). It will help researchers understand the changes that happen after surgery and how to better manage health during this transition.
HelsinkiAges 35–50 - NCT07586111Recruiting
Plant Foods for Better Gut and Heart Health
This study tests whether eating more plant-based foods improves your gut bacteria, digestion, and heart health markers. You'll follow a structured diet plan for several weeks while providing blood, stool, and urine samples to measure changes.
LondonAges 30–70 - NCT07282418RecruitingPhase 1/Phase 2
Study on recreation and health habits
This trial explores how recreational activities affect your health and well-being. You'll use your phone to answer quick surveys and may be asked to try new recreational activities.
Chicago, IllinoisAges 18 years+ - NCT06861153Recruiting
Study on eating more beans and lentils for heart health
This trial looks at whether eating more beans, lentils, chickpeas, and peas (called pulses) over 12 weeks can improve your heart and metabolic health. It is for people who currently eat less than 1.5 cups of these foods per week and are willing to add more to their diet.
Tucson, ArizonaAges 18–75 - NCT06013046Recruiting
Wheelchair exercise program for better heart health
This study tests a physical activity training program designed for wheelchair users to improve heart and metabolic health. You will attend weekly exercise sessions and your fitness levels will be monitored throughout the program.
St Louis, MissouriAges 18 years+ - NCT06544915Recruiting
Synbiotic vs. probiotic for heart and gut health
This study tests whether a synbiotic (a combination of probiotics and prebiotics) is better than a probiotic alone or a placebo for improving gut health and heart health. If you are a healthy adult who hasn't taken antibiotics recently and has few heart disease risk factors, you may be able to join.
Saratoga Springs, New YorkAges 18–60 - NCT05838508Recruiting
Exercise timing study to improve heart and body health
This trial studies how different exercise patterns affect heart-related and metabolic health (things like blood sugar and cholesterol). You may be asked to follow a specific exercise schedule and related testing if you’re healthy enough to exercise safely.
Boston, MassachusettsAges 18–45 - NCT04055428RecruitingPhase 2
Testing a hormone supplement to improve heart and metabolic health
This study tests whether adding a natriuretic peptide medicine improves heart health and metabolism in Black adults. It may help with blood pressure and related health markers, but you must meet specific health and safety criteria.
Birmingham, AlabamaAges 18 years+ - NCT04256330Recruiting
Testing how diet and health affect inflammation recovery
This study looks at how “cardiometabolic health” and inflammation signals change, and how quickly they improve (“resolution”). It may help people whose bodies have ongoing inflammation, by testing approaches that support healthier recovery.
Gothenburg, Västra Götaland CountyAges 18–65 - NCT04427462Recruiting
Study of energy balance and heart health in children
This study looks at how children’s “energy use” relates to heart and metabolism health. It may help doctors understand what healthy and unhealthy patterns look like in kids.
Little Rock, ArkansasAges 8–10 - NCT04482374Recruiting
Puberty blockers and heart/metabolic health in teens
This study looks at how puberty suppression (puberty blockers) may affect heart health and metabolism in children who are early in puberty. It may help researchers understand who benefits most and what changes happen during treatment.
Aurora, ColoradoAges 9–14 - NCT04596592Recruiting
Puberty blockers and estradiol effects on heart health
This study looks at how puberty blockers and then estradiol (estrogen) may affect heart and metabolism health in teens. It may help doctors understand risks and benefits for transgender youth starting gender-affirming hormone care.
Aurora, ColoradoAges 13–16 - NCT05516277Recruiting
Insomnia care study for older adults with PTSD
This study tests a treatment plan for insomnia (trouble sleeping) in older adults who also have post-traumatic stress disorder (PTSD). The goal is to see whether improving sleep also supports heart and metabolic health (such as blood sugar and heart-related measures).
North Hills, CaliforniaAges 50 years+ - NCT05838950Recruiting
Short high-intensity exercise program for cardiometabolic health
This trial studies whether a structured, short high-intensity exercise program can improve health markers related to weight, blood sugar, and blood fats in young adults with obesity. It may help you see if this kind of exercise leads to measurable health improvements.
Syracuse, New YorkAges 18–25
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Common questions
- Are there clinical trials for cardiometabolic health?
- Yes. Clin2 currently lists 81 recruiting cardiometabolic health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiometabolic health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiometabolic health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.