Clinical trials
Cardiovascular Risk Factor clinical trials
Below are recruiting cardiovascular risk factor clinical trials, each written for real people, not researchers. We’re tracking 131 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07581431RecruitingPhase 1
Testing ISM8969 in healthy and obese adults with heart disease risk
This early-stage trial tests a new drug called ISM8969 to see if it's safe and how the body handles it. Participants are either healthy adults or adults who are overweight with risk factors for heart disease, like high blood pressure or high cholesterol.
Melbourne, VictoriaAges 18–80 - NCT05768464RecruitingPhase 2
Surgery aftercare for non-clear kidney cancer at high risk
This Phase 2 trial studies an after-surgery treatment for people with non-clear types of kidney cancer who are at high risk of coming back. It aims to lower the chance of recurrence by giving extra therapy after your tumor is completely removed.
Nanjing, JiangsuAges 18–75 - NCT07613294RecruitingPhase 3
Testing lepodisiran to reduce heart plaque buildup
This study tests whether a new medicine called lepodisiran can shrink plaque in heart arteries for adults with high Lp(a) (a type of cholesterol linked to heart disease) who have had a heart event or are at serious risk. The trial uses CT scans to monitor changes in your arteries.
La Jolla, CaliforniaAges 45–80 - NCT05920863RecruitingPhase 2
Lenvatinib, immunotherapy, plus liver artery treatment before surgery
This Phase 2 trial tests whether giving lenvatinib and immunotherapy along with TACE (a liver artery treatment) before surgery can lower the risk of hepatocellular carcinoma coming back after surgery. It targets people with certain higher-risk early-stage liver tumors (CNLC IB/IIA).
Hangzhou, ZhejiangAges 18–75 - NCT06324981Recruiting
AI text messages to help your heart health
This study tests if text messages from an AI program can help you improve your heart health habits, like taking medication on time and managing blood pressure, cholesterol, or diabetes.
Denver, ColoradoAges 18–89 - NCT00001853Recruiting
Heart Disease Risk Factors in Black Adults
This study examines why Black men and women have different heart disease risk factors, focusing on weight, cholesterol levels, and diabetes risk. Researchers want to understand these differences to help prevent heart disease in Black communities.
Bethesda, MarylandAges 18–70 - NCT05888467Recruiting
Exercise study for women at risk of pregnancy heart problems
This study looks at how physical activity affects the heart and blood-vessel health “profile” in women who have risk factors for a pregnancy condition (called GHD, related to preeclampsia risk). It may help researchers find safer or more helpful activity guidance before pregnancy.
Diepenbeek, LimburgAges 18–50 - NCT07000357RecruitingPhase 3
Study of AZD0780 to reduce heart attack and stroke risk
This trial tests a new medication, AZD0780, to see if it helps prevent major cardiovascular events like heart attacks or strokes in people who already have heart or blood vessel disease, or are at high risk for a first event. It might be a good fit if your cholesterol isn't well-controlled despite current treatments.
Athens, AlabamaAges 18 years+ - NCT04263038RecruitingPhase 4
Watchful waiting versus blood thinners for small lung clots
This trial compares close monitoring (“watch and wait”) versus taking the blood thinner rivaroxaban in people with a small type of lung blood clot. It aims to find out whether low-risk patients can safely avoid or reduce anticoagulation while still staying healthy.
Woluwe-Saint-Lambert, Brussels CapitalAges 18 years+ - NCT07230847Recruiting
Healing of drug-coated vs. standard stents in high-bleeding-risk patients
This trial compares two types of stents (a drug-coated stent and a standard drug-eluting stent) in people with acute coronary syndrome who also have a high risk of bleeding. It uses a special camera to look at how the artery heals one month after the stent is placed.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05859048Recruiting
Care plan to help high-risk people spot heart failure early
This trial tests a multidisciplinary care approach aimed at helping people with high risk for heart failure get diagnosed earlier. It may help you catch heart failure sooner if it starts, so treatment can begin earlier.
Vancouver, British ColumbiaAges 40 years+
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Common questions
- Are there clinical trials for cardiovascular risk factor?
- Yes. Clin2 currently lists 131 recruiting cardiovascular risk factor studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cardiovascular risk factor trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cardiovascular risk factor trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.