Clinical trials
Caries clinical trials
Below are recruiting caries clinical trials, each written for real people, not researchers. We’re tracking 124 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07377240Recruiting
Understanding barriers to changing eating habits in families with severe tooth decay in young children
This study talks to parents of young children (under 6) with severe early childhood cavities to understand what makes it hard to change risky eating habits. The goal is to help dentists support families better.
Clermont-FerrandAges Any age - NCT06898918Enrolling by invitation
Mothers' feeding habits and kids' eating and tooth health
This study looks at how mothers control their child's eating, how the child eats, and whether it relates to early childhood cavities. It may help families understand what affects their preschooler's dental health.
CairoAges 3–5 - NCT06957509Recruiting
Saliva test to predict cavities in 3-year-olds
This study looks at proteins in the spit of 3-year-old children to see if they can help doctors better predict which kids might get cavities. The goal is to improve how we assess cavity risk at a young age.
StockholmAges 3–3 - NCT06293521RecruitingPhase 2
Nerve treatment options for deep cavities in baby teeth
This study compares two ways to treat severe cavities in baby teeth: removing only the infected part of the nerve (pulpotomy) versus removing all the nerve tissue (pulpectomy). It looks at which method helps the tooth heal better and stay healthy longer.
CairoAges 4–6 - NCT03969628Recruiting
Testing two ways to check tooth-caries risk in children
This study compares two different methods of estimating how likely a child is to get tooth decay. If you visit the children’s dental clinic, the researchers will use these methods to help identify risk and plan prevention.
Pelotas, Rio Grande do SulAges 7–11 - NCT05979805Recruiting
Education programs to prevent cavities and gum problems during braces
This study compares two types of education programs to see which better prevents cavities and gum inflammation in people getting braces. Participants must be new to orthodontic treatment and have healthy teeth and gums at the start.
BogotáAges 13–28 - NCT07648212Recruiting
AI Tool for Detecting Tooth Decay in Dental Training
This study tests whether artificial intelligence can help dental students and residents better detect early tooth decay (cavities) between teeth. Participants will learn to use an AI tool and compare it to traditional detection methods to see if it improves accuracy.
Ann Arbor, MichiganAges 18–99 - NCT06514885Recruiting
Silver diamine fluoride for root cavities in older adults
This trial studies a special liquid called silver diamine fluoride that is painted onto cavities on tooth roots. It may help stop the decay and keep the tooth healthy without drilling.
Hong KongAges 60 years+ - NCT06608563Recruiting
Dental sealant study for kids and molars
This study tests a special adhesive to help sealants stick better and prevent cavities on back teeth in children aged 6 to 12.
Dublin, DublinAges 6–12 - NCT06727110Recruiting
New liquid treatment for tooth cavities
This study tests a new method to treat cavities that reach the middle layer of a tooth. It may help repair the tooth with a liquid that hardens into a filling. If you have a back tooth with a cavity that hasn't been filled yet, you might be eligible to join.
San Francisco, CaliforniaAges 18–64 - NCT06826456Recruiting
Laser treatment to prevent cavities in children's molars
This study tests whether a special laser (Er,Cr:YSGG) can prevent cavities in the deep grooves of children's permanent back teeth. It is for children ages 6–12 who are calm during dental visits and have healthy, groove-filled molars without visible cavities.
AlexandriaAges 6–12 - NCT06999005Recruiting
Dental cavity treatment study for children ages 6-12
This study tests two gentle cavity treatments for children's permanent molars. It aims to find which method works best over two years.
Santos, São PauloAges 6–12 - NCT07041164Recruiting
Light vs X-ray for finding cavities in kids' back teeth
This trial tests a new light-based tool (near-infrared light) compared to traditional X-rays to find hidden cavities between baby molars. The goal is to see if the light method is better at spotting cavities and if kids like it more.
BangkokAges 4–10 - NCT07068204Recruiting
Comparing two toothpastes to prevent cavities in healthy adults
This study tests whether a new 2% calcium hypophosphite toothpaste is better than standard fluoride toothpaste at preventing cavities. You may be able to join if you have healthy teeth and are willing to use an electric toothbrush and floss.
Bialystok, PolandAges 18–45 - NCT07213661Recruiting
Long-term results of two cavity treatments
This study looks at how well two cavity treatments work over time. It's for people who already took part in an earlier study at one of 33 housing sites.
Cleveland, OhioAges 62 years+ - NCT07241052Recruiting
Probiotic spray for cavities in kids
This study tests a probiotic spray that you use in your mouth to help stop cavities from getting worse and to prevent new ones. It is for children ages 7–10 who already have at least one cavity.
Hà Nội, Sơn TâyAges 7–10 - NCT07242742Recruiting
Pulpotomy vs. root canal for deep cavities
This trial compares two treatments for very deep cavities that reach the tooth's nerve. It tests whether a less invasive partial nerve removal (pulpotomy) works as well as a full root canal. It may help you keep your tooth without needing a full root canal.
SingaporeAges 12 years+ - NCT01499394Recruiting
Biorepository study for adults who can consent
This study collects and stores samples (such as tissue or other biological materials) for future research. It mainly seeks adults who can agree to participate after understanding what it involves.
Mobile, AlabamaAges 18 years+ - NCT05733676Recruiting
MI Paste Plus vs resin for white spots after braces
This trial compares two tooth treatments to see which one works better for “white spot” areas that can appear after braces come off. If you have mild plaque buildup and at least one white spot on front teeth, you may be eligible to test one of these options and improve tooth surface healing.
Edmonton, AlbertaAges 12–21 - NCT07555223Recruiting
Using 3D Scans to Better Detect Tooth Decay
This study tests whether special 3D imaging and intraoral scanning tools can help dentists better identify tooth decay and plaque buildup. Researchers want to see if these new methods work well and could improve how cavities are diagnosed.
Wondelgem, BotestraatAges 18–70 - NCT07611981Recruiting
Tooth Decay and Oral Health in Children With Learning Disabilities
This study compares tooth decay and brushing habits between children with specific learning disabilities and healthy children. Researchers want to understand if children with learning disabilities need special dental care strategies.
Alanya, AntalyaAges 7–12 - NCT07262086Enrolling by invitation
Bioactive filling for deep cavities in back teeth
This trial tests a new type of self-hardening tooth-colored filling material that may help repair and protect deep cavities in back teeth. It is looking for people with two molars that need deep fillings, to see if the material stays strong and helpful over time.
Ismailia, IsmaliaAges 21–45 - NCT07136155Enrolling by invitation
Two ways to treat deep cavities in baby teeth
This study compares two ways to treat deep cavities in baby (primary) molars. One method places a special soothing medicine under a filling; the other uses a metal crown that covers the whole tooth. Both aim to keep the tooth healthy without needing a nerve treatment or extraction.
IrbidAges 4–9 - NCT07762651Enrolling by invitation
Tooth-colored fillings for back teeth compared
This study compares two types of tooth-colored filling materials for back teeth. It aims to see which one lasts longer and works better.
Tanta, TantaAges 25–40
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Common questions
- Are there clinical trials for caries?
- Yes. Clin2 currently lists 124 recruiting caries studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a caries trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a caries trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.