Clinical trials
Central Nervous System Diseases clinical trials
Below are recruiting central nervous system diseases clinical trials, each written for real people, not researchers. We’re tracking 209 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06054295Recruiting
Twin study of childhood brain tumors
This study looks at genetic differences between identical twins where only one twin has a childhood brain or spinal cord tumor. It helps researchers understand why some children get cancer and others don't.
Minneapolis, MinnesotaAges Up to 18 years - NCT06088121Recruiting
TMS with cognitive training for mild Alzheimer's dementia
This study tests a combination of brain stimulation (TMS) and cognitive training to improve memory and thinking in people with mild Alzheimer's. It may help if you are already on a stable dose of a donepezil-type medication and have a confirmed Alzheimer's diagnosis.
Incheon, Bupyeong 6(yuk)-dong, Bupyeong-guAges 60–85 - NCT06121336Recruiting
Precision medicine in stroke: studying a brain protein
This study looks at a protein called brain-derived tau in the blood of people who have had a stroke. It aims to learn more about stroke and find better ways to treat it.
Munich, BavariaAges 18 years+ - NCT06193252Recruiting
Exercising to slow Parkinson's in iRBD
This study tests whether a specific amount of exercise can slow the development of Parkinson's disease in people who have a sleep condition called iRBD. If you have iRBD and are not very active, researchers will help you start a personalized exercise program and track your progress with a smartphone app.
Nijmegen, GelderlandAges 50 years+ - NCT06295263Recruiting
AI for diagnosing and treating brain diseases in older adults
This study uses artificial intelligence to help diagnose and treat brain diseases that affect older adults, such as Parkinson's and Alzheimer's. Researchers will compare AI methods with standard care to see if they can improve diagnosis and treatment.
Jinan, ShandongAges 8–100 - NCT06303869Recruiting
Deep brain stimulation for speech after stroke
This study tests if deep brain stimulation (a small device implanted in the brain) can improve speech and arm movement after a stroke that affected the deeper parts of the brain. It is designed for people who have trouble speaking clearly (dysarthria) from their stroke.
Pittsburgh, PennsylvaniaAges 18–75 - NCT06418048Recruiting
Infectious disease registry and biobank trial
This study collects medical information and optional biological samples (like blood or saliva) from people with an active or suspected infection. The goal is to build a large database that can help researchers better understand infectious diseases and develop new ways to diagnose and treat them.
MilanAges 18 years+ - NCT06418698Recruiting
Brain artery calcium and clot removal outcomes
This study looks at whether calcium buildup in brain arteries affects how well clot removal (mechanical thrombectomy) works for stroke patients. You may be able to join if you have a large artery blockage, a CT scan was done, and you are having the clot removal procedure.
Guangzhou, GuangdongAges 18 years+ - NCT06446245RecruitingPhase 2
Doxycycline for brain tuberculosis
This trial tests whether adding the antibiotic doxycycline to standard treatment can improve recovery in patients with tuberculosis of the brain (TB meningitis). It may help reduce brain swelling and damage.
Medan, MedanAges 21 years+ - NCT06467773Recruiting
PET/MRI scan to track brain inflammation in stroke and MS
This study uses a special kind of PET/MRI scan to look at inflammation in the brain and spinal cord. It may help people with conditions like stroke, multiple sclerosis, or other immune-related brain diseases.
Wuhan, HubeiAges 18 years+ - NCT06502015Recruiting
Biomarkers in nervous system autoimmune diseases
This study looks for biomarkers (biological clues) in people with autoimmune diseases of the nervous system. It aims to discover better ways to diagnose and treat these conditions.
WuhanAges 18 years+ - NCT06553625Recruiting
RF ablation study for pain or CNS conditions
This study observes how well a Boston Scientific radiofrequency (RF) system works for treating pain or central nervous system (CNS) conditions. It helps researchers understand real-world benefits for patients scheduled for this procedure.
CologneAges Any age - NCT06556199RecruitingPhase 1/Phase 2
Study of selinexor combo for returning brain lymphoma
This trial tests a new combination of drugs (selinexor, temozolomide, and an immunotherapy) for people whose primary central nervous system lymphoma has come back or stopped responding to previous treatment. The goal is to see if this combination can help shrink or control the lymphoma.
Hanzhou, ZhejiangAges 18–75 - NCT06570681Recruiting
Video call assessment for acute stroke
This trial tests whether a video call with a doctor can help assess stroke symptoms quickly in the ambulance or emergency setting. It aims to see if this approach speeds up care and improves outcomes for people with possible stroke.
Aabenraa, Region SyddanmarkAges 18 years+ - NCT06633809Recruiting
Treating minor stroke with large artery blockage
This study tests whether a specific treatment (likely endovascular therapy) helps people who have a minor stroke caused by a blockage in a large brain artery. If you are eligible, you may receive this treatment within 24 hours of your stroke to try to improve your recovery.
Hangzhou, ZhejiangAges 18 years+ - NCT06712810RecruitingPhase 1
Q702 for blood cancers and histiocytic disorders
This study tests an experimental pill called Q702 for people with certain blood cancers and related disorders (like histiocytoses, myelofibrosis, and lymphomas) that have not responded to standard treatments. It aims to see if Q702 is safe and effective.
Scottsdale, ArizonaAges 18 years+ - NCT06817577RecruitingPhase 1
Study of NG004 for recent spinal cord injury
This trial tests a new medicine called NG004 for people who have recently had a spinal cord injury in the neck area (cervical spine) and still have some movement and feeling. The goal is to see if it can help improve recovery.
BayreuthAges 18–70 - NCT06871969Recruiting
Testing a brain-wave device for stroke triage in ambulances
This trial is testing a portable EEG device (a non-invasive cap that measures brain activity) to help ambulance staff quickly determine if a patient is having a stroke. It aims to speed up diagnosis and care for people with suspected stroke symptoms.
Amsterdam, North HollandAges 18 years+ - NCT06946407Recruiting
Chemotherapy combination for brain lymphoma
This trial tests a combination of chemotherapy drugs to treat lymphoma that started in your brain. The goal is to see if this treatment helps without having to use whole-brain radiation.
ChangchunAges Up to 60 years - NCT06954610Recruiting
Heart Check for Stroke Risk in Atrial Fibrillation
This trial uses heart imaging to better understand stroke risk in people with atrial fibrillation (an irregular heartbeat). It may help doctors decide on the best treatment to prevent another stroke.
BernAges 18 years+ - NCT07014943RecruitingPhase 2
High-dose chemo and stem cell transplant for brain lymphoma
This trial tests a combination of high-dose chemotherapy drugs (gemcitabine, busulfan, and thiotepa) followed by a stem cell transplant for people with primary central nervous system lymphoma. It aims to see if this treatment can improve outcomes for patients whose disease has responded to initial therapy.
Chengdu, SichuanAges 16–70 - NCT07056348Recruiting
Brain stimulation to improve movement in Parkinson's or tremor
This study tests brain stimulation in a region called VOP/VIM to see if it can improve motor function. It is for people with movement disorders who are already getting deep brain stimulation (DBS) surgery.
Pittsburgh, PennsylvaniaAges 18–80 - NCT07137494RecruitingPhase 1
CAR T-cell therapy for CNS lymphoma
This trial tests a new type of CAR T-cell therapy (MB-CART19.1) for people with central nervous system lymphoma (CNSL) that has come back or not responded to treatment. It aims to see if this therapy can help treat the lymphoma in the brain or spinal fluid.
Basking Ridge, New JerseyAges 18 years+ - NCT07143045Recruiting
Zorifertinib for lung cancer that has spread to the brain
This trial tracks how well zorifertinib works as a first treatment for people with a specific type of advanced lung cancer that has spread to the brain or spinal cord lining. Participants may receive zorifertinib or another standard treatment, and researchers will monitor their response over time.
Hefei, AnhuiAges 18 years+
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Common questions
- Are there clinical trials for central nervous system diseases?
- Yes. Clin2 currently lists 209 recruiting central nervous system diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a central nervous system diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a central nervous system diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.