Clinical trials
Children clinical trials
Below are recruiting children clinical trials, each written for real people, not researchers. We’re tracking 2,992 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04627766Recruiting
Check whether continuous vital-sign monitoring works in children
This trial studies whether a connected patch can continuously monitor vital signs in children in the intensive care unit (ICU) safely and effectively. It may help care teams spot changes sooner using ongoing measurements.
Montreal, QuebecAges birth–18 years - NCT05382338RecruitingPhase 3
Sodium thiosulfate to protect hearing in medulloblastoma
This Phase 3 study tests whether adding sodium thiosulfate during treatment for newly diagnosed medulloblastoma can reduce the risk of hearing loss. It is designed for children and teens whose cancer meets specific low-risk or average-risk tumor and lab features.
Birmingham, AlabamaAges 4–21 - NCT05402813Recruiting
Study of hearing loss in children with GJB2 or OTOF gene changes
This study follows children with hearing loss caused by changes in specific genes (GJB2 or OTOF). It helps researchers understand how hearing develops over time and how children may do with or without cochlear implants.
ParisAges Up to 16 years - NCT05374590Enrolling by invitationPhase 2/Phase 3
Long-term safety study of efgartigimod for young myasthenia gravis patients
This trial checks the long-term safety of efgartigimod given through an IV and as a quick under-the-skin injection in children with generalized myasthenia gravis (gMG). It may help your care team understand how safely this treatment can be used over time for kids who already took related study treatments.
Chicago, IllinoisAges 2–18 - NCT05368662Recruiting
Studying sleep and life quality in children on home ventilation
This study checks how sleep and overall quality of life change for children who use non-invasive breathing support at home. It also uses questionnaires to understand what helps or harms sleep and daily comfort so families and care teams can improve support.
Angers, Maine et LoireAges 6 months–17 years - NCT05374824Recruiting
Palliative surgery versus more seizure medicines for Lennox-Gastaut
This trial compares two treatment approaches for children with Lennox-Gastaut syndrome: palliative (comfort-focused) surgery versus adding more anti-seizure medicines. It aims to see which option works better for seizure control and day-to-day well-being.
Chicago, IllinoisAges Up to 26 years - NCT05383911Recruiting
Sickle cell care plan choices for teens and young adults
This trial tests a way to help teens and young adults with sickle cell disease (SCD) and their caregivers actively take part in treatment decisions. It focuses on improving shared decision-making through interviews and a partner-centered approach.
Wilmington, DelawareAges 15 years+ - NCT05407480Recruiting
Treatment guidance study for children with Hodgkin lymphoma
This study is for children with “classical” Hodgkin lymphoma to help guide the best treatment plan. It may help your care team choose therapy based on what has worked for similar children.
Paris, FranceAges birth–18 years - NCT05384288Recruiting
How kids with blood cancers respond to the flu vaccine
This study looks at how children with blood cancers respond to the seasonal flu shot. It may help doctors understand what protection the vaccine provides for pediatric oncology patients.
Memphis, TennesseeAges Up to 18 years - NCT05407129Recruiting
Improve hospital safety by sharing your recent experience
This trial asks patients, families, caregivers, and hospital staff to report what happened during a recent hospital stay to help improve safety. Your feedback may help the hospital change processes that prevent problems for others.
Boston, MassachusettsAges Any age - NCT05377372Recruiting
Study of early exposures in babies with sickle cell disease
This study asks mothers of babies with sickle cell disease about early-life exposures and related factors. It may help researchers understand what might affect health in the first months of life.
Birmingham, AlabamaAges 18–50 - NCT05386134Recruiting
Adaptive eye imaging for inherited and acquired retinal conditions
This study tests a special high-detail camera that takes clearer pictures of the retina (the light-sensing layer at the back of the eye). It may help researchers better understand different retinal diseases—and your results could support future diagnosis and care.
Toronto, OntarioAges 5–70 - NCT05361811Recruiting
Therapy coaching for parents of children with rare genetic syndromes
This trial tests an “Acceptance and Commitment Therapy” program for parents or legal guardians who feel moderate parenting stress. It aims to help caregivers cope in healthier ways and may also improve how they manage stress while supporting their child.
Bethesda, MarylandAges 18 years+ - NCT04439552Recruiting
MRI study during cornea cross-linking for keratoconus
This trial uses an MRI scan (and a close-up eye scan) to study what happens in the cornea during treatment for keratoconus. It may help doctors better understand how treatment works and who benefits most.
Boston, MassachusettsAges 8–35 - NCT05319353RecruitingPhase 3
Maribavir for kids with CMV after transplant
This Phase 3 trial tests maribavir (an anti-CMV medicine) in children and teens who get CMV infection after a stem cell or solid organ transplant. It aims to see whether the drug is safe and well-tolerated, and whether it can reduce the virus in the body.
Wilmington, DelawareAges Up to 17 years - NCT05334823RecruitingPhase 2
CAR T-cell treatment for CD19-positive relapsed leukemia in children
This Phase 2 trial tests pCAR-19B, a customized immune-cell treatment for children and teens with CD19-positive B-ALL that has come back or did not respond to standard therapy. If eligible, you would receive the cell infusion after cell collection and testing to make sure the leukemia cells have the right marker.
Beijing, Beijing MunicipalityAges 3–21 - NCT05319067Recruiting
Gut bacteria study in toddlers on long-term reflux antibiotics
This study compares gut bacteria (microbiome) in toddlers who take an antibiotic to prevent urine infections for vesicoureteral reflux, versus other similar children. It may help researchers understand how long-term antibiotic use and reflux affect gut health and future risk.
MontpellierAges 1–3 - NCT05354622Recruiting
Genetic testing study for inherited leg stiffness
This study looks at genes (DNA) to understand an inherited condition that causes gradually worsening leg stiffness. It may help researchers learn what causes the condition and potentially guide future care.
Boston, MassachusettsAges 1 month–30 years - NCT05304585RecruitingPhase 3
Chemo for children with early, low-risk fusion-negative rhabdomyosarcoma
This Phase 3 study tests a chemotherapy plan for children and teens with newly diagnosed, very low-risk or low-risk rhabdomyosarcoma that does not have certain gene fusions (FOXO1 fusion negative). The goal is to see if this treatment can work well while limiting side effects by matching therapy to early-stage risk.
Birmingham, AlabamaAges Up to 21 years - NCT05297708Recruiting
Blood pressure monitoring at home, office, and with a 24-hour device
This study compares blood pressure readings taken at home, in the doctor's office, and over a full 24-hour period using a portable monitor. It may help understand the best way to track blood pressure in children and teens with slightly high blood pressure.
Cincinnati, OhioAges 6–19 - NCT05268250Recruiting
Program to help school families cope with type 1 diabetes stress
This trial tests a structured program and screening approach to help school-age children and their families who are feeling significant stress about diabetes. It may help by identifying distress early and offering targeted support alongside an intensive diabetes care plan.
Jacksonville, FloridaAges 8–65 - NCT05261477Recruiting
Kid Brain Injury Education and Care Navigation Program
This trial tests a family support program that teaches caregivers and helps coordinate outpatient care after a traumatic brain injury. It may help families better understand recovery and connect with rehabilitation services.
Colorado Springs, ColoradoAges 3 years+ - NCT05277272Recruiting
Registry study for children with HLH
This study is a disease registry that collects medical information from children who have hemophagocytic lymphohistiocytosis (HLH) or are suspected to have it. It helps doctors better understand HLH and how it affects patients over time.
Cincinnati, OhioAges Any age - NCT05294042Recruiting
Patient navigators for children’s mental health care
This study tests a support program that helps children and caregivers find and get community mental health services, especially in high-poverty areas. It may help by making it easier to connect with the right services and stay engaged while waiting or starting care.
Chicago, IllinoisAges Up to 14 years
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Common questions
- Are there clinical trials for children?
- Yes. Clin2 currently lists 2,992 recruiting children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.