Clinical trials
Children clinical trials
Below are recruiting children clinical trials, each written for real people, not researchers. We’re tracking 2,992 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04093986Recruiting
Using past pregnancy records from women with sickle cell
This study looks back at past pregnancy and breastfeeding experiences in women with sickle cell disease who took hydroxyurea. It aims to better understand how hydroxyurea exposure may affect pregnancy and baby outcomes.
Cincinnati, OhioAges Any age - NCT04091724Recruiting
EEG monitoring during surgery to reduce delirium in children
This study checks whether using an EEG machine (small sensors that record brain electrical activity) during elective surgery can help prevent or lessen emergence delirium—confusion and agitation right after waking up. It focuses on children under 16 and compares their experience around the time they come out of anesthesia.
Wuhan, HubeiAges Up to 16 years - NCT04060030RecruitingPhase 2
Leucovorin for young children with autism language difficulties
This Phase 2 study tests whether leucovorin (a vitamin-related medicine) can improve social communication and language in young children with autism. It also looks at safety and whether the results hold while the child stays on their usual therapies and routines.
Phoenix, ArizonaAges 2.5 years–5 years - NCT04117360Recruiting
Speech therapy study for people after jaw alignment surgery
This study looks at how well people can make specific speech sounds before and after jaw alignment treatment. It may help researchers understand whether speech patterns improve with treatment in people with certain bite differences.
Chapel Hill, North CarolinaAges 15–40 - NCT04068012Recruiting
Test of a decision support tool for children with PARDS
This trial tests a computer “decision support” tool to help the care team manage treatment for children with PARDS who are just starting a breathing machine. It may help clinicians choose care steps and potentially support safer, more effective breathing management during the first days of ventilation.
Chicago, IllinoisAges 1 month–18 years - NCT01073475Recruiting
Pregnancy and birth registry for community health research
This trial is a long-term registry that collects pregnancy and birth information in a community to help researchers study maternal and newborn health. It may help you and others by improving understanding of care and outcomes across many pregnancies.
Birmingham, AlabamaAges Any age - NCT03959085RecruitingPhase 3
Inotuzumab plus chemotherapy for high-risk childhood leukemia
This Phase 3 trial tests whether adding inotuzumab to standard post-induction chemotherapy improves outcomes for children and young teens with high-risk B-ALL, mixed phenotype acute leukemia (MPAL), or certain high-risk B-LLy. It may help by targeting leukemia cells more directly, but participation depends on specific age, lab results, and medical history rules.
Birmingham, AlabamaAges 12 months–25 years - NCT03910465Recruiting
Study for children and adults with chordoma
This trial studies people with chordoma (a rare bone/soft-tissue tumor) and collects information and samples to learn more about the disease. It may help by improving understanding of chordoma and supporting future research.
Bethesda, MarylandAges 2 years+ - NCT04014829Recruiting
Study of pain processing after planned hysterectomy
This trial looks at how the nervous system and fear of pain may affect pain after a planned hysterectomy. If you qualify, you may be asked about pain levels and pain sensitivity to better understand who may have more pain recovery challenges.
SingaporeAges 21–80 - NCT04006808RecruitingPhase 1/Phase 2
Shingles prevention vaccine study for kids with kidney transplants
This study tests whether an investigational shingles (herpes zoster) vaccine is safe and helps prevent shingles in children who have had a kidney transplant. Because these children take medicines to prevent rejection, the study specifically looks at vaccine effects in this higher-risk group.
BrusselsAges 1–17 - NCT03969329RecruitingPhase 3
Etelcalcetide for children on dialysis with high parathyroid hormone
This Phase 3 trial tests etelcalcetide to lower a hormone called parathyroid hormone (PTH) in children who have kidney disease and secondary hyperparathyroidism while on hemodialysis. It may help control bone/mineral problems, but the study also checks heart rhythm safety and medication stability.
GhentAges 2–17 - NCT03972345Enrolling by invitation
Study on how sticking to growth hormone affects near adult height
This study looks at whether consistently taking growth hormone (Norditropin) helps children reach a height goal by “near final height.” It focuses on children who are short due to growth hormone deficiency or born small for gestational age.
UlmAges birth–15 years - NCT03980886Recruiting
Study of inflammation in children with eosinophilic esophagitis
This study looks at how inflamed the esophagus is in children who have eosinophilic esophagitis (EoE). It may help doctors better understand what’s driving symptoms like trouble swallowing and food getting stuck.
San Diego, CaliforniaAges 1–65 - NCT03889743RecruitingPhase 4
Steroid treatment to help prevent asthma after a first wheezing illness
This trial studies whether an early steroid treatment can lower the chance that children will go on to develop asthma after their first severe “wheezing” episode caused by a rhinovirus (a common cold virus). If you qualify, the goal is to prevent future asthma rather than just treat the current episode.
TurkuAges 3 months–1.9 years - NCT03911388RecruitingPhase 1
HSV G207 for Children with Recurrent Cerebellar Brain Tumors
This trial is testing a virus called HSV G207, which is injected directly into the tumor, to treat children and young adults with a type of brain tumor in the cerebellum that has come back or not responded to standard treatments.
Birmingham, AlabamaAges 3–22 - NCT03893643Recruiting
Skin and mouth symptoms of NF2 in children under 15
This study looks at skin and mouth problems that children with NF2 may have. It helps doctors learn more about NF2 symptoms in kids, which may lead to better care.
NiceAges birth–15 years - NCT03983369RecruitingPhase 3
Laser treatment to help prevent painful mouth sores from chemo
This trial tests whether low-level laser therapy (using special light on the mouth) can prevent or reduce mouth sores caused by chemotherapy in children and young adults. It may help you avoid painful inflammation that can affect eating, comfort, and treatment.
Villejuif, Val de MarneAges 4–25 - NCT03931707Recruiting
Genetic study of newborns in China
This study collects genetic information from very young newborns to better understand early-life health. Your child’s information may help researchers learn about genetics and future research.
Shanghai, Shanghai MunicipalityAges Up to 4 weeks - NCT03915418Recruiting
Screening sleep problems in children with cerebral palsy
This trial checks a new way to find sleep problems in children with cerebral palsy using connected tools (like devices/apps). It mainly helps by making sleep screening easier and more accurate, so families can get the right next steps sooner.
AngersAges 6–15 - NCT03739827Recruiting
Study rare solid tumors and collect your health samples
This study follows people (and sometimes family members) connected to rare solid tumors and collects health information and samples (biospecimens). It helps researchers understand how these cancers develop and builds resources for future research, which may benefit you by contributing to better tailored care for rare cancers.
Bethesda, MarylandAges 4 weeks+ - NCT03810196Recruiting
Stem cell addback after transplant to treat viral or fungal infection
This study tests a stem cell “addback” treatment after a specific type of transplant (with certain immune cells removed). It may help the body recover faster and fight serious viral or fungal infections in children and teens.
Philadelphia, PennsylvaniaAges Up to 25 years - NCT03822741Recruiting
Seizure causes and treatments in newborns and infants
This study looks at what causes certain serious seizures that start early in life, and how to treat them. It may help doctors better match treatments to the seizure cause in newborns and young infants.
Shanghai, Shanghai MunicipalityAges Up to 1 year - NCT03772119Recruiting
Child surgery follow-up study for a spine bone shape issue
This study follows children aged 3–10 who need surgery for a specific type of spine bone shape problem (hemivertebra). It aims to track outcomes after the operation and how well follow-up is completed.
BordeauxAges 3–10 - NCT03810651RecruitingEarly Phase 1
Radiation planning for kidney tumors in children and teens
This early study tests a type of radiation delivery (“pencil beam scanning”) for certain kidney cancers in children and teens. It may help doctors better target the tumor while reducing radiation to nearby healthy tissue.
Philadelphia, PennsylvaniaAges birth–30 years
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Common questions
- Are there clinical trials for children?
- Yes. Clin2 currently lists 2,992 recruiting children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.