Clinical trials
Children clinical trials
Below are recruiting children clinical trials, each written for real people, not researchers. We’re tracking 2,992 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04338048Recruiting
Study for autosomal dominant polycystic kidney disease
This study enrolls people who have been diagnosed with autosomal dominant polycystic kidney disease (ADPKD), a genetic kidney condition that can cause kidney cysts. It aims to learn about this specific form of the disease so better care is possible for the right patients.
Washington D.C., District of ColumbiaAges Up to 18 years - NCT04371900Recruiting
Study children of mothers using birth control access in Michigan
This study looks at children ages 0 to 17 whose mothers took part in a Michigan program to access birth control. Researchers will track child and family outcomes to understand how improving access to contraception can affect families.
Ann Arbor, MichiganAges birth–17 years - NCT04293042RecruitingEarly Phase 1
BK virus treatment using donor immune cells after transplant
This early-phase study tests whether immune cells made from a donor (T cells) can treat BK virus infection in people whose immune system is weak after a stem cell transplant or chemotherapy. It may help control the virus causing bladder/urinary symptoms.
Philadelphia, PennsylvaniaAges 1 month–25 years - NCT04318678RecruitingPhase 1
CD123 CAR T-cell therapy for relapsed leukemia and related cancers
This early-phase study tests a lab-made immune therapy (CD123 CAR T cells) for children and young adults up to age 21 whose cancer has come back or didn’t respond to treatment. The goal is to see if these CAR T cells can find and attack cancer cells that carry a marker called CD123.
Memphis, TennesseeAges Up to 21 years - NCT04372875Recruiting
Help for teens using health tech in the emergency room
This trial tests whether using a health information technology tool in the emergency department can improve sexual health care and reduce health disparities for teens. It focuses on gathering survey and screening information so care can better meet needs.
Washington D.C., District of ColumbiaAges 15–21 - NCT04289467RecruitingPhase 2
Fenfluramine for stubborn infantile spasms
This Phase 2 trial studies fenfluramine to treat infantile spasms that haven’t improved after standard medicines (ACTH and vigabatrin). If you/your child has ongoing seizures, the study may offer another treatment option and will monitor safety closely, especially heart-related side effects.
Los Angeles, CaliforniaAges 1–3 - NCT04216927RecruitingPhase 3
Neonates on heart-lung bypass get NO to prevent kidney injury
This Phase 3 study tests whether not giving nitric oxide during heart-lung bypass in newborns helps reduce the risk of acute kidney injury. It focuses on newborns having heart surgery for congenital heart disease.
Cincinnati, OhioAges 1 day–1 month - NCT04230356RecruitingPhase 2
Viral immune T-cells for viral infections after stem cell transplant
This Phase 2 study tests donor-made immune T-cells that specifically target viruses to treat or prevent viral infections after a stem cell transplant. It may help your body control dangerous viruses like adenovirus, CMV, EBV, and BK virus, while checking safety with different timing of the treatment.
Cincinnati, OhioAges Any age - NCT04156893RecruitingPhase 1/Phase 2
RH-matched blood transfusions for sickle cell patients
This study tests whether giving red blood cells matched to your child’s RH (a blood marker) can improve safety and fit for people with sickle cell disease who need regular transfusions. It may help reduce mismatches by using blood units selected to match the child’s blood type more closely.
Philadelphia, PennsylvaniaAges 6 months+ - NCT04165746Recruiting
Early care program for very young children in foster systems
This study looks at how an early support program affects the development of infants who are newly entering institutional care or foster care in the São Paulo area. It may help families and caregivers support healthy growth during a critical first period.
São Paulo, São PauloAges Up to 2 years - NCT04195347RecruitingPhase 1/Phase 2
CM4620 to lessen pancreatitis after asparaginase
This study tests CM4620 to reduce how severe pancreatitis becomes in children and young people with leukemia/lymphoma who develop pancreatitis after receiving a drug called asparaginase. It aims to improve outcomes by calming the inflammation of the pancreas.
Charlotte, North CarolinaAges Up to 21 years - NCT04174066Recruiting
Study on kidney damage in children and adults with MGLS or FSGS
This trial collects medical data and blood/urine samples from patients with minimal change disease or focal segmental glomerulosclerosis (FSGS) to better understand how the immune system damages kidney cells.
NiceAges 1 year+ - NCT04201704Recruiting
Less IV fluids for children after trauma
This trial studies whether giving children less fluid through a vein after serious injury helps them recover safely. Children are enrolled soon after arrival to the ICU so the team can compare outcomes between different fluid amounts.
Buffalo, New YorkAges 6 months–15 years - NCT04185038RecruitingPhase 1
CAR T therapy through a catheter for pediatric brain tumors
This Phase 1 trial tests a personalized immune-cell treatment (CAR T) delivered directly in the brain-area space using a catheter. It may help children and young adults with hard-to-treat (recurrent or refractory) diffuse midline brain tumors like DIPG/DMG when standard options aren’t working.
Seattle, WashingtonAges 1–26 - NCT04160910RecruitingPhase 2
Studying 5HTP to manage asthma symptoms in kids
This Phase 2 study tests whether 5HTP can help regulate asthma in children and teens who have mild to moderate asthma linked to allergies. It may be an option if your symptoms are allergy-related and you can follow study visits and questionnaires.
Indianapolis, IndianaAges 8–18 - NCT04181138Recruiting
Study of childhood primary sclerosing cholangitis types
This study follows children and young adults with primary sclerosing cholangitis (PSC) to understand the condition and how it shows up on scans or biopsy. It may help doctors better recognize PSC and choose the best next steps for care.
Los Angeles, CaliforniaAges 2–25 - NCT04213547Recruiting
Sleep and blood sugar control in teens with type 2 diabetes
This study looks at how sleep timing and length relate to blood sugar control in teens with type 2 diabetes. It also checks whether teens who meet certain sleep and blood-sugar targets—and can follow sleep tracking—can take part in the study and feedback sessions.
Philadelphia, PennsylvaniaAges 12–20 - NCT04086329RecruitingPhase 1
Testing an oxygen sensor during exercise in muscle disease
This early (Phase 1) study checks whether a tiny oxygen-sensing device works reliably while people with mitochondrial muscle disease (and some healthy volunteers) ride a stationary bike. The goal is to see if the sensor can measure oxygen use during exercise and help future monitoring or research.
Philadelphia, PennsylvaniaAges 18–65 - NCT04041713RecruitingPhase 2
Antioxidant drink trial for children with Rett syndrome
This Phase 2 trial studies whether an antioxidant “cocktail” helps children and teens with Rett syndrome compared with a placebo (inactive drink). If you join, you’ll get study assessments and blood tests to see if the treatment is safe and helpful.
Toronto, OntarioAges 2–21 - NCT04117360Recruiting
Speech therapy study for people after jaw alignment surgery
This study looks at how well people can make specific speech sounds before and after jaw alignment treatment. It may help researchers understand whether speech patterns improve with treatment in people with certain bite differences.
Chapel Hill, North CarolinaAges 15–40 - NCT04093986Recruiting
Using past pregnancy records from women with sickle cell
This study looks back at past pregnancy and breastfeeding experiences in women with sickle cell disease who took hydroxyurea. It aims to better understand how hydroxyurea exposure may affect pregnancy and baby outcomes.
Cincinnati, OhioAges Any age - NCT04118712Recruiting
Ovarian tissue banking for girls and teens having ovary surgery
This study collects small pieces of ovarian tissue during certain surgeries in girls and teens (before or after puberty). The goal is to bank the tissue for possible future fertility or medical research.
Chicago, IllinoisAges Up to 18 years - NCT04098445Recruiting
Study of lung injury in children after stem cell transplant
This study follows children and teens who get a stem cell transplant to learn how lung problems develop over time. Your participation could help doctors better predict, prevent, and manage lung injury after transplant.
San Francisco, CaliforniaAges Up to 24 years - NCT04032990Enrolling by invitation
Testing a skin-based nerve stimulation for kids’ arm function
This trial studies whether a painless, skin-based treatment (stimulation over the spine) is safe and feasible to improve arm and hand function in children with a spinal cord injury. It’s mainly designed to see if the approach can be done safely and whether it may help upper-limb skills.
Louisville, KentuckyAges 4–18
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Common questions
- Are there clinical trials for children?
- Yes. Clin2 currently lists 2,992 recruiting children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.