Clinical trials
Cholesterol clinical trials
Below are recruiting cholesterol clinical trials, each written for real people, not researchers. We’re tracking 49 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07071181Recruiting
Milk-based drinks for better sleep and health
This trial tests whether drinking a milk-based drink every day for four weeks can improve gut health, sleep quality, and heart health. It may be a good option if you have trouble sleeping and are overweight.
Leeds, West YorkshireAges 40–70 - NCT07028749RecruitingPhase 2
Study of an experimental drug for high triglycerides and remnant cholesterol
This trial tests an investigational medication, MAR001, to see if it can lower high levels of fats in the blood (triglycerides and remnant cholesterol) linked to heart disease. If you have these conditions, this treatment might help reduce your risk.
Anniston, AlabamaAges 18–75 - NCT07027033Recruiting
Oleic acid's effect on cholesterol metabolism in women with obesity
This study tests whether a special type of fatty acid (oleic acid) can change how the body handles cholesterol in women with obesity who are having weight-loss surgery. It will help researchers understand if this nutrient can improve cholesterol metabolism and reduce insulin resistance.
Nantes, FranceAges 18–60 - NCT07012629RecruitingPhase 3
Preventing future strokes after silent brain infarcts
This study tests whether blood thinners and/or cholesterol-lowering medications can prevent future strokes in people who have small, silent brain infarctions found on MRI. If you've never had a stroke or TIA before, and are not already on similar medications, you may be a candidate.
AalborgAges 50 years+ - NCT06988462Recruiting
Bottarga supplement for metabolic health
This study tests a supplement called bottarga, made from fish eggs, to see if it improves cholesterol, blood sugar, or weight in people with metabolic problems like high cholesterol or prediabetes. It is a small pilot study for Massachusetts residents.
Sommerville, MassachusettsAges 18–60 - NCT06936111Recruiting
Can extra cholesterol-lowering help after a stent?
This trial looks at whether stronger cholesterol-lowering medicine can reduce the risk of future heart problems in people who already have a stent. It focuses on people who still have other mildly narrowed spots in their arteries.
ShanghaiAges 18–75 - NCT06915025RecruitingPhase 3
Study of a new drug for advanced ovarian cancer
This trial tests a new drug called IMNN-001 combined with standard chemotherapy for women with advanced ovarian, fallopian tube, or peritoneal cancer. The goal is to see if adding this drug can improve safety and effectiveness.
Orlando, FloridaAges 18 years+ - NCT06919302Recruiting
Digital heart health app for heart disease patients
This study tests a digital heart health app combined with lifestyle coaching to help people with heart disease or diabetes manage their cholesterol and overall heart health. It aims to see if the app can improve outcomes for people already taking a statin.
Toronto, OntarioAges 45 years+ - NCT06812767Enrolling by invitation
Chronic disease risks in working-age people
This study looks at risk factors for chronic diseases in healthy working-age adults. You may help researchers understand how to prevent conditions like heart disease or diabetes.
MoscowAges 18 years+ - NCT06726590Recruiting
Gene testing for better medication outcomes
This study collects blood, urine, and cheek swabs, along with health information, to see how your genes affect your response to medications. You may be eligible if you take many medications or are on blood pressure or depression medication.
Bryan, TexasAges 18 years+ - NCT06504043Enrolling by invitationPhase 1
Safety study of HST101 in healthy Chinese adults with high cholesterol
This study tests a new drug, HST101, to see if it is safe for healthy Chinese people with high cholesterol. It is an early-phase trial, so it focuses on safety first.
Chengdu, SichuanAges 18–55 - NCT06471036Recruiting
Improving cholesterol testing and treatment after a heart attack
This study tests whether giving extra education to doctors and patients can help improve cholesterol management after a heart-related hospitalization. It aims to see if a simple program can make sure patients get the right testing and treatment for high cholesterol.
Minneapolis, MinnesotaAges 18 years+ - NCT06437574RecruitingPhase 2
Cholesterol-lowering and immune response in prostate cancer
This trial tests whether taking a daily cholesterol-lowering medication (Vytorin or ezetimibe) can boost your immune system to help fight prostate cancer. It is for men with low- or intermediate-risk prostate cancer who are on active surveillance and planning a biopsy.
Los Angeles, CaliforniaAges 18 years+ - NCT06217588Recruiting
LCAT Deficiency Natural History Study
This study tracks people with LCAT deficiency over time to learn more about how the condition affects the body. It does not test a treatment, but helps researchers understand the disease better so they can design future studies.
Philadelphia, PennsylvaniaAges Any age - NCT06222632Enrolling by invitation
MIND diet and forest bathing for heart and mind
This study tests whether a brain-healthy diet (MIND diet) combined with relaxing walks in nature (forest bathing) can help protect your heart and improve your mood. It is for Chinese adults aged 50–75 who have high cholesterol and some anxiety.
Hong KongAges 50–75 - NCT03770312RecruitingPhase 4
Testing low/moderate statin use to prevent heart problems in older adults
This study looks at whether taking a low- to moderate-dose statin can prevent first-time heart and stroke problems in people age 70 and older. It may help you lower “bad cholesterol” (LDL) and see if that leads to fewer heart events over time.
SeoulAges 70 years+ - NCT05693701Recruiting
Lifestyle and study program for blood donors with high cholesterol
This study tests a multicomponent program for people who donate blood and have high cholesterol that fits familial hypercholesterolemia criteria. It may help lower cholesterol, but you must not already be on cholesterol-lowering medicines.
Dallas, TexasAges 18–75 - NCT05641753RecruitingPhase 4
LDL-lowering study for adults with type 1 diabetes
This study looks at cholesterol lowering in adults with type 1 diabetes and whether it reduces “residual risk,” meaning risk that may remain even with current care. You may be asked to take cholesterol-focused treatment and complete blood tests to track LDL (“bad cholesterol”).
New York, New YorkAges 18–89 - NCT05488431RecruitingPhase 2
Bempedoic acid to lower cholesterol and inflammation in HIV
This Phase 2 trial studies whether bempedoic acid can lower cholesterol and inflammation in people with HIV who are already on effective HIV medications. It may help reduce signs of artery inflammation that can contribute to heart and stroke risk.
Los Angeles, CaliforniaAges 40 years+ - NCT05047354Recruiting
Study cholesterol metabolism in rare genetic conditions
This study looks at body chemistry (cholesterol-related lab findings) and physical features in people with Smith-Lemli-Opitz syndrome and related rare genetic cholesterol disorders. It may help researchers better understand these conditions and how they affect the body.
Bethesda, MarylandAges 1 day–100 years - NCT04903223RecruitingPhase 1
Testing how fat in the liver affects statin use in kids
This early study tests whether “liver fat” changes how a statin (rosuvastatin) works in children and teens. It may help doctors choose safer or more effective dosing in kids based on biology and a specific genetics marker.
Kansas City, MissouriAges 8–21 - NCT04798430Enrolling by invitationPhase 3
Study drug follow-up for LDL reduction in high-risk cholesterol patients
This Phase 3 study looks at the long-term safety and benefit of OLE LIB003 for people with very high cholesterol or heart disease risk who still need lower LDL (“bad cholesterol”). It’s likely a continuation study for participants who already did earlier LIB003 Phase 3 trials.
Evanston, IllinoisAges 10 years+ - NCT04485871Recruiting
Omega-3 supplements to lower diabetes risk in at-risk adults
This trial tests whether taking omega-3 fatty acids can reduce risk factors for developing diabetes in people with normal cholesterol but other risk factors. You might be asked to follow study visits and dietary/health restrictions for about 33 weeks.
Montreal, QuebecAges 45–74 - NCT04178915Enrolling by invitation
Blood marker study to predict severe bacterial lung infection
This study looks at specific immune cells and how fats are transported in the blood to predict which people will have a severe bacterial infection (like pneumonia or sepsis). Your results may help doctors identify higher-risk patients earlier.
MinskAges 18–60
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Common questions
- Are there clinical trials for cholesterol?
- Yes. Clin2 currently lists 49 recruiting cholesterol studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cholesterol trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cholesterol trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.