Clinical trials
Chronic Back Pain clinical trials
Below are recruiting chronic back pain clinical trials, each written for real people, not researchers. We’re tracking 331 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06724679Recruiting
Virtual reality for chronic back pain treatment
This trial tests if using a virtual reality (VR) headset can help people with long-term lower back pain during a spine rehabilitation program. It will see if VR is a practical and helpful addition to the program.
AngersAges 18–65 - NCT07559890Recruiting
Nerve ablation for low back pain with Modic changes
This study tests a procedure that uses heat to stop a nerve in the lower back from sending pain signals. It may help people with long-term central low back pain who have not gotten better with other treatments and have Modic changes on MRI.
PragueAges 18 years+ - NCT06113185Recruiting
Pain Scale Study for Low Back Pain
This study tests a pain scale for people with long-term low back pain. It is a questionnaire study, not a treatment trial, so you will fill out forms about your pain.
Istanbul, None SelectedAges 18–55 - NCT06741579RecruitingPhase 3
Pain relief study for nerve injury pain
This trial tests how well two types of peripheral nerve stimulation (PNS) devices relieve chronic pain caused by a single nerve injury. It looks for people who already have a referral for PNS therapy as part of their usual care and who have gotten at least 50% relief from a diagnostic nerve block.
Palo Alto, CaliforniaAges 18 years+ - NCT07719699Recruiting
Vibration and Pilates for chronic low back pain
This study tests if whole-body vibration or Pilates exercises can reduce pain and improve balance and movement in people with long-lasting low back pain. It aims to find a helpful treatment for chronic back pain that has lasted more than 12 weeks.
Lahore, Punjab ProvinceAges 18–40 - NCT06310226Recruiting
Studying spinal cord stimulation for chronic low back pain
This study is looking at how people with chronic low back pain respond to spinal cord stimulation (a device that sends gentle electrical pulses to the spine to reduce pain). If you already have a spinal cord stimulator, you may help researchers understand how well it works and how it affects your brain.
Los Angeles, CaliforniaAges 18–80 - NCT06471920Recruiting
Telerehab for chronic low back pain in rural areas
This study tests whether a video-based physical therapy program can help people with chronic low back pain who live in rural areas. If you qualify, you'll get telerehabilitation (rehab done at home through video calls) to reduce pain and improve function.
Baltimore, MarylandAges 18 years+ - NCT06474429Recruiting
Movement test for chronic low back pain recovery
This study tests whether a simple movement screening test can help physical therapists decide when someone with chronic lower back pain is ready to stop treatment. If you join, you will do a few basic movements to see how your back is doing.
Plano, TexasAges 18–49 - NCT06025201Recruiting
Brain activity markers for chronic low back pain
This study uses a safe, non-invasive cap with sensors (EEG) to measure your brain activity and look for patterns linked to chronic low back pain. It aims to better understand pain so doctors can improve treatments.
Palo Alto, CaliforniaAges 18–80 - NCT05780021Recruiting
Support program for long-term low back pain after rehab
This trial tests whether a structured motivational support program can help people with long-term low back pain after they finish a rehab program. It may help you stay motivated and improve your day-to-day progress after treatment.
ParisAges 18 years+ - NCT07415941Recruiting
Mindfulness and nerve stimulation for back pain and depression
This trial tests if combining mindfulness-based meditation with a gentle nerve stimulation device (applied to the ear) can help people aged 50–85 with chronic low back pain and depression. The goal is to reduce pain and improve mood without changing your current medications.
Tallahassee, FloridaAges 50–85 - NCT06453291Recruiting
Comparing treatments for chronic low back pain
This study compares different ways to treat chronic low back pain that has lasted more than 3 months. It aims to find which approach works best for adults aged 40 to 60.
LahoreAges 40–60 - NCT06491121Recruiting
Can high-intensity training with a smartphone help chronic back pain?
This trial tests if a technology-supported high-intensity exercise program can help adults with chronic low back pain. You'll use your own smartphone to help guide the training and attend regular therapy sessions.
Wilrijk, AntwerpenAges 18–65 - NCT07211464Recruiting
ACT plus exercise for older adults with chronic low back pain
This study tests whether combining acceptance and commitment therapy (ACT) with exercise helps older adults manage ongoing low back pain. If you've had pain for at least 3 months and it's been bothering you, this approach might teach you new ways to cope and move better.
Hong KongAges 60 years+ - NCT06796881Recruiting
Comparison of two therapies for long-term low back pain
This study compares two hands-on treatments for people with chronic low back pain. One uses special tools to massage tight muscles, while the other uses gentle pressure on muscle knots. Both aim to help you move better and feel less pain.
CairoAges 25–45 - NCT06859957RecruitingPhase 3
Melatonin for chronic low back pain
This trial tests if melatonin can help reduce chronic low back pain. If you have had low back pain for at least 3 months that limits your daily activities, this study might be for you.
RotterdamAges 18–65 - NCT06915896Recruiting
Chronic back or neck pain: predicting therapy outcomes
This study looks at people with long-term low back or neck pain who are waiting for physical therapy. It aims to find what factors predict how well they will do with different treatment paths.
Florence, FIAges 18 years+ - NCT07222462Recruiting
Radiofrequency ablation for chronic low back pain
This study tests if radiofrequency ablation, a procedure that uses heat to block pain signals from the facet joints in your spine, can help people with long-term low back pain that hasn't improved with other treatments like physical therapy.
Atlanta, GeorgiaAges 18 years+ - NCT06709963Recruiting
Brain stimulation for older adults with chronic back or knee pain
This study tests a type of brain stimulation called intermittent theta burst stimulation to see if it can reduce pain and improve thinking in older adults with long-term back or knee pain. The treatment involves a non-invasive procedure that uses magnetic pulses to stimulate the brain.
Hong KongAges 60–85 - NCT06804551Enrolling by invitation
Freezing vs. heating nerve treatment for chronic low back pain
This trial compares two treatments that target the small nerves in the back that can cause long-term pain. One treatment uses cold to freeze the nerves, and the other uses heat to block them. The goal is to see which works better for people with chronic low back pain.
Kansas City, KansasAges 18 years+ - NCT06944730Recruiting
Trunk muscle training for better movement and balance in low back pain
This study tests whether trunk muscle training can improve the quality of your movements and balance if you have chronic low back pain. It is designed for people with moderate pain and no other major health issues.
Hong KongAges 18–55 - NCT06771713Recruiting
Brief Pain Reprocessing Therapy for Veterans with Chronic Back Pain
This trial tests a type of talk therapy called Brief Pain Reprocessing Therapy for Veterans with long-term low back pain. The therapy is done over video calls, so you can join from home. It aims to help retrain how your brain processes pain signals.
Ann Arbor, MichiganAges 18 years+ - NCT06940063Recruiting
Music therapy for chronic low back pain
This trial tests whether an active music-based program can help reduce chronic low back pain. It is for adults aged 18 to 65 whose pain has lasted at least 3 months and has been present on most days.
Denton, TexasAges 18–65 - NCT07470307Recruiting
Exercise for chronic low back pain: Pilates vs. strength training
This trial compares dynamic lumbar strengthening exercises to Pilates, both combined with myofascial release, for people with ongoing low back pain. It aims to find which approach works better for reducing pain and improving function.
Lahore, Punjab ProvinceAges 25–35
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Common questions
- Are there clinical trials for chronic back pain?
- Yes. Clin2 currently lists 331 recruiting chronic back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.