Clinical trials
Chronic Back Pain clinical trials
Below are recruiting chronic back pain clinical trials, each written for real people, not researchers. We’re tracking 331 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06888895Recruiting
Stretching for tight hamstrings in low back pain
This study compares two types of hamstring stretching techniques (passive vs. active-passive) to see which one improves flexibility more in people with chronic low back pain. It may help you if your hamstrings feel tight and your pain has lasted at least 3 months.
Cébazat, FranceAges 18–65 - NCT07058376Enrolling by invitation
Herbal medicine for chronic low back pain
This trial tests whether a herbal medicine strategy can safely and effectively reduce chronic low back pain lasting over 3 months. It may be an option if your pain has been moderate to severe and you are looking for alternative treatments.
Seoul, Gangnam-GuAges 19–69 - NCT06902233Recruiting
Brain stimulation for chronic low back pain
This trial tests if a non-invasive brain stimulation technique can help people with long-lasting low back pain. It uses mild electrical currents to adjust brain activity and may reduce pain and improve daily function.
Dunedin, OtagoAges 18–75 - NCT07681336Recruiting
Ear nerve stimulation for chronic low back pain
This trial tests if stimulating the vagus nerve through the ear can reduce chronic low back pain in people who haven't gotten enough relief from painkillers. It aims to see if this non-invasive treatment can help manage pain without medication.
Ghent, Oost-VlaanderenAges 30–60 - NCT06828016Recruiting
Foot Reflexology for Chronic Low Back Pain
This study tests whether foot reflexology—a gentle massage of the feet—can help relieve chronic low back pain that has lasted more than 12 weeks. It is a safe, non-drug approach that may be a good option for people looking for a natural way to manage their pain.
New Taipei CityAges 18–100 - NCT06821607Recruiting
Telerehab for chronic low back pain
This study tests if online rehabilitation therapy can help people with ongoing low back pain. You would connect with a specialist from home.
Baltimore, MarylandAges 18–64 - NCT06706479Enrolling by invitation
Brain stimulation for balance in older adults with back pain
This study tests whether a gentle, non-invasive electrical brain stimulation technique (called high-definition tDCS) can improve balance in older adults with chronic low back pain. Participants receive either real or sham stimulation during balance training sessions.
Hong Kong, Hong KongAges 60–85 - NCT06619418Recruiting
Home Device Using Sound and Body Stimulation for Back Pain
This study is testing a take-home device that uses sound and gentle body stimulation to help with long-term back pain. It is for adults with chronic low back pain who live near the University of Minnesota and are not taking certain sleep or anxiety medications.
Minneapolis, MinnesotaAges 18 years+ - NCT05963451Recruiting
Testing treatments for long-term low back pain from facet joints
This study focuses on people with long-lasting low back pain that likely comes from the small “facet” joints in the lower spine. It aims to better understand brain, psychological, and biology changes to help optimize treatment for this type of back pain.
Sherbrooke, QuebecAges 18–75 - NCT06568198RecruitingPhase 2
Brain stimulation study for chronic low back pain
This trial tests whether a noninvasive brain stimulation technique called tACS can help reduce chronic low back pain. Participants will have brain scans and receive the treatment over several sessions.
Charlestown, MassachusettsAges 18–60 - NCT07675304RecruitingEarly Phase 1
Mesotherapy for chronic low back pain study
This trial tests whether injecting a natural substance (collagen) into the lower back can safely reduce chronic pain. It may help people with pain that hasn't spread to the legs.
WarsawAges 18–65 - NCT07244913Recruiting
Tools for chronic low back pain relief
This trial compares two types of handheld tools—one with metal instruments and one that uses sound waves—to see which works better for long-term low back pain. It may help if you have had pain for at least 6 months and feel tightness in your hamstrings.
Lahore, Punjab ProvinceAges 40–55 - NCT06355414RecruitingPhase 1
Psilocybin for chronic back pain and depression
This trial tests if psilocybin, a psychedelic drug, can help people with long-term low back pain who also have depression. If you qualify, you'll receive psilocybin in a controlled setting, and researchers will see how it affects your pain and mood.
Baltimore, MarylandAges 21–80 - NCT07193212Recruiting
Osteopathic treatment for low back pain and leg health
This study tests whether a hands-on osteopathic treatment can improve how your legs and feet work if you have chronic low back pain. It may help you understand if this type of manual therapy is a good option for your pain.
Auburn, AlabamaAges 18–65 - NCT07028034Recruiting
Six-minute step test for chronic back pain
This trial uses a simple step test to measure how chronic low back pain affects your daily function. It may help doctors better understand your condition without needing expensive equipment.
KırşehirAges 18–65 - NCT07719452Enrolling by invitation
Strengthening exercise for chronic low back pain
This study tests if adding a specific low back strengthening exercise to standard physical therapy helps people with long-lasting low back pain. It is for Tricare beneficiaries who have had back pain for at least 3 months without leg pain.
Fort Sam Houston, TexasAges 18–65 - NCT07645859Recruiting
High-Intensity vs. Moderate Exercise for Chronic Lower Back Pain
This trial compares two types of exercise programs—one with short, intense bursts of activity and one with steady, moderate activity—to see which works better for people with long-lasting lower back pain that has no clear medical cause. You would participate in supervised exercise sessions over several weeks.
KarachiAges 20–48 - NCT07241559Recruiting
Low back pain treatment study: injection and mobilization
This study tests two treatments for chronic low back pain: a special injection of dextrose (a sugar solution) guided by ultrasound, and a technique to mobilize the fascia (connective tissue) in the lower back. It aims to see if these help people who haven't found relief from standard treatments.
Ankara, AltındağAges 18–65 - NCT07742111Recruiting
Virtual reality for long-term low back pain
This study tests whether virtual reality exercises can help people with chronic low back pain feel better and move more comfortably. You might join if you have had low back pain for a while, your pain is moderate, and you have some fear of movement.
AmaranteAges 18 years+ - NCT07386548Recruiting
Biologic injection for low back disc problems
This study tests if an injection can help people with a herniated disc in the lower back who have not gotten better with other treatments and are already planning surgery. It aims to see if the injection can reduce symptoms and possibly avoid or improve surgery outcomes.
Manhattan, New YorkAges 18 years+ - NCT07724704Recruiting
Exercise comparison for long-term low back pain
This study compares two sets of exercises (called McGill and Sahrmann) to see which is better at reducing chronic low back pain. If you have had non-specific low back pain for more than 12 weeks, this trial may help you strengthen your core and feel better without surgery or medication.
Lahore, Punjab ProvinceAges 20–50 - NCT07696741Recruiting
Pain Reprocessing Therapy for Chronic Lower Back Pain
This study tests a type of talk therapy called pain reprocessing therapy (PRT) for adults with chronic lower back pain. The goal is to see if PRT can help reduce pain and improve quality of life.
Toronto, OntarioAges 18–65 - NCT07251959Enrolling by invitation
Exercise vs. exercise plus manual therapy for chronic back pain
This study tests whether a workplace exercise program, with or without hands-on manual therapy, can help reduce chronic spinal pain in desk workers. It is designed for UCAM University staff who have had persistent back pain for at least 3 months.
Murcia, MurciaAges 18 years+ - NCT07426562Recruiting
Stretching vs. Dry Needling for Tight Hamstrings in Chronic Back Pain
This trial tests two treatments for tight hamstrings in people with long-lasting low back pain: a special stretch and dry needling (thin needles placed in trigger points). It aims to find which helps reduce tightness and pain.
Peshawar, Khyber PakhtunkhwaAges 20–50
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Common questions
- Are there clinical trials for chronic back pain?
- Yes. Clin2 currently lists 331 recruiting chronic back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.