Clinical trials
Chronic Disease Management clinical trials
Below are recruiting chronic disease management clinical trials, each written for real people, not researchers. We’re tracking 174 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06782100Recruiting
MRI-Guided Treatment for Severe Leg Artery Blockages
This study uses MRI to guide treatment of blocked leg arteries below the knee, aiming to improve blood flow and reduce severe pain or sores.
Houston, TexasAges 18 years+ - NCT04027244Recruiting
Studying care plans for severe leg blood flow problems
This study looks at how best to manage severe leg ischaemia, a condition where blood flow to the leg is dangerously reduced. It mainly involves patients who are planning an intervention, and some participants may also do special heart imaging tests.
Leicester, LeicestershireAges 18–110 - NCT06233110RecruitingPhase 1
Ruxolitinib and fostamatinib for steroid-resistant chronic GVHD
This study tests two drugs, ruxolitinib and fostamatinib, together for people with chronic graft-versus-host disease (GVHD) that hasn't responded well to steroids. The goal is to see if this combination can better control GVHD.
Durham, North CarolinaAges 18–80 - NCT07323914RecruitingPhase 3
Pain management for people with Alzheimer's and chronic pain
This study tests if opioid pain medicine is safe and effective for people with Alzheimer's disease who also have chronic pain. It aims to find better ways to manage pain in dementia.
BeijingAges 50–90 - NCT05086432Recruiting
Test sputum-guided care to reduce cough in lung scarring
This study uses analysis of mucus (sputum) to guide treatment with the goal of reducing long-lasting cough in adults with interstitial lung disease (ILD). You may be asked to provide sputum samples and may receive treatment decisions based on those results.
Hamilton, OntarioAges 18 years+ - NCT07091019Recruiting
CML patient experience study on standard TKI therapy
This study tracks the experiences and health outcomes of people with chronic myeloid leukemia (CML) who are taking approved first or second line tyrosine kinase inhibitor (TKI) medicines. It helps doctors learn how these treatments work in everyday care.
Birmingham, AlabamaAges 18–100 - NCT06609772Recruiting
Pain education for liver donors after surgery
This trial tests an individualised pain education program to see if it can reduce chronic pain and improve quality of life for living liver donors after their surgery.
Malatya, BattalgaziAges Any age - NCT07754721Recruiting
Diet and lifestyle program for chronic acid reflux
This study tests a comprehensive program that combines diet and lifestyle changes to help people with chronic acid reflux (heartburn, acid regurgitation, or chest pain) feel better. It looks at how these changes can improve your overall health and reduce symptoms.
Hualien City, TaiwanAges 18–79 - NCT06773169Recruiting
Testing an app for self-managing chronic conditions
This study tests a smartphone or computer app designed to help people with long-term health conditions like arthritis, heart disease, or stroke manage their own recovery. The goal is to see if using the app improves daily living and reduces disability.
Hamilton, OntarioAges 44–75 - NCT06387706Recruiting
Web-based pain program for older adults
This study tests a fun, web-based program (GAP) to help older adults manage chronic pain through light exercise and coping skills. It's designed for Cantonese speakers who can use a smartphone.
Hong KongAges 60 years+ - NCT07235501Recruiting
Studying immune cells in chronic GVHD after stem cell transplant
This study looks at immune cells in the blood and tissues of people who have had a stem cell transplant. It aims to understand chronic graft-versus-host disease (GVHD), a common complication, so doctors can better detect and treat it.
Duarte, CaliforniaAges 7 years+ - NCT06001541Recruiting
Web program for veterans and caregivers managing health
This study tests a web program to help Veterans and their caregivers work together to manage long-term health conditions like pain, diabetes, or depression. You will join with your live-in caregiver to learn self-management skills online.
Palo Alto, CaliforniaAges 18 years+ - NCT05274854Recruiting
Practice change study for severe unexplained gut symptoms
This study looks at a new approach to care for adults with severe, long-lasting stomach or bowel symptoms when no clear cause has been found. It may help you get more coordinated support through an integrated care clinic.
Woolloongabba, QueenslandAges 18–90 - NCT07048808RecruitingPhase 2
Gene therapy for chronic chest pain
This trial tests a new gene therapy (XC001) delivered through a thin tube into your heart's blood vessels. It aims to grow new blood vessels to relieve chest pain in people with chronic angina who have no other treatment options.
Cincinnati, OhioAges 18–85 - NCT04852406Recruiting
Care plan study for people on blood thinners having abdominal surgery
This study looks at whether a structured (protocol-based) care plan before and around surgery improves outcomes for people taking blood-thinning medicines. It may help teams plan safer timing and monitoring to reduce complications around the operation.
Beijing, Beijing MunicipalityAges Any age - NCT03460769Recruiting
Mixed meal test to study diabetes from pancreas conditions
This study uses a special blood-sugar test (a mixed meal) to better diagnose and understand diabetes related to pancreatic cancer or chronic pancreatitis, and to compare it with other diabetes types. It may help researchers find clearer ways to tell these diabetes causes apart and understand how they work.
Los Angeles, CaliforniaAges 30–84 - NCT07291154Recruiting
Using an app to improve dialysis quality
This trial tests if a smartphone app (via WeChat) can help people on dialysis better manage their treatment and improve quality of care. It's for adults who have been on regular dialysis for at least 3 months.
Chongqing, Chongqing MunicipalityAges 18–75 - NCT06075602Recruiting
Complex and calcified coronary artery disease: a registry study
This study watches how people with complex or calcified heart artery disease are treated (with stents or bypass surgery) and how they do over time. It aims to learn which treatments work best for tough blockages.
Lucerne, Canton of LucerneAges 18 years+ - NCT07147296Recruiting
Implant to manage blood pressure swings after spinal cord injury
This trial tests an implanted device that may help control drops in blood pressure caused by spinal cord injury. If you often feel dizzy or lightheaded due to low blood pressure, this study could explore whether the device improves stability.
Little Rock, ArkansasAges 18–75 - NCT05870969Recruiting
Digital monitoring to catch liver cancer risk early
This study tests a digital (computer/phone-based) system to help track people with higher risk of liver cancer so cancers can be found earlier. It may help by guiding regular check-ins and making early diagnosis more efficient.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07286578Recruiting
Using heart CT scans to guide treatment for blocked arteries
This trial is testing whether a special heart CT scan (coronary CT angiography) can help doctors better understand and treat calcium buildup in your heart arteries. If you have a type of heart disease that might need a stent or other procedure, this study could help decide the best approach.
Boston, MassachusettsAges 18–85 - NCT07695363Recruiting
Restrictive fluids in liver transplant
This trial tests if giving less fluid during liver transplant surgery helps recovery. It is for adults with end-stage liver disease receiving a transplant.
Vancouver, British ColumbiaAges 18 years+ - NCT06011551Recruiting
Gel injection for painful lumbar discs
This trial tests a gel (HYDRAFIL-D) injected into painful discs in your lower back to see if it relieves pain. It's for people whose back pain hasn't improved with other treatments.
Birmingham, AlabamaAges 22–85 - NCT05649098RecruitingEarly Phase 1
Testing dupilumab for itchy inherited genetic skin disorders
This early trial tests whether dupilumab can reduce itching in people with certain inherited (genetic) inflammatory skin conditions. It may help by calming skin inflammation that causes ongoing itch and sleep problems.
Chicago, IllinoisAges 6 months+
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Common questions
- Are there clinical trials for chronic disease management?
- Yes. Clin2 currently lists 174 recruiting chronic disease management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.