Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,257 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05733832Recruiting
Transitional care after hospital discharge for serious liver disease
This trial tests an extra support program after you leave the hospital to help people with advanced liver disease avoid complications and stay on track. It may help by providing structured follow-up soon after discharge.
Chicago, IllinoisAges 18 years+ - NCT06402851RecruitingPhase 4
Blood thinner or none for atrial fibrillation with dialysis
This trial compares two types of blood thinners (vitamin K antagonists and factor Xa inhibitors) versus no blood thinner in people with atrial fibrillation who are on dialysis or have very advanced kidney disease. It aims to see which option is safest and most effective for preventing strokes and bleeds.
Salvador, Estado de BahiaAges 18 years+ - NCT07330362Recruiting
AI to help diagnose kidney disease from biopsy
This trial tests an artificial intelligence system that helps doctors analyze kidney tissue samples. If you have chronic kidney disease and need a biopsy, this study will see if the AI can improve diagnosis.
Guangzhou, GuangdongAges 15–79 - NCT02000895Recruiting
Studying birth factors in preterm and term mother-infant pairs
This study looks at how biological factors at birth differ between preterm and term babies, and how they relate to the mother and baby together. It may help doctors better understand early-life influences for newborn care.
Miami, FloridaAges Up to 10 years - NCT02723500Recruiting
Xenon MRI scan for people with chronic lung disease
This study tests whether a special MRI scan using xenon gas can be done safely and provide useful information in people with chronic lung conditions. You may be able to take part if your breathing tests and oxygen levels are adequate and you can complete the MRI safely.
London, OntarioAges 18–85 - NCT07518719Recruiting
Nutrition and Wellness Program for Kidney Disease
This study tests whether a nutrition and wellness program helps people with early-stage kidney disease manage their condition better. The program combines nutrition guidance, support for lifestyle changes, and care coordination to help protect kidney health.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07626710Recruiting
How Heart Valve Replacement Affects Kidney Function
This study looks at whether a minimally invasive heart valve procedure (TAVI) affects how well your kidneys work. Researchers will track your kidney function before and after the procedure using blood tests to understand any changes.
Roma, RMAges 18 years+ - NCT07777445Recruiting
Oxygen treatment during exercise for lung and pulmonary vascular disease
This study compares breathing normal air versus low-flow liquid oxygen during exercise to see if oxygen helps improve performance in people with conditions affecting the lungs or the blood vessels in the lungs. You would exercise while using a portable oxygen device and then without it to compare the effects.
Zurich, Canton of ZurichAges 18 years+ - NCT05868668Recruiting
Low-intensity shockwave versus wave therapy for erectile and pelvic pain
This trial compares two types of low-intensity wave therapy to see which works better for erectile dysfunction and/or chronic pelvic pain. Participants may benefit if these therapies improve erection quality and reduce pelvic pain.
Cleveland, OhioAges 40 years+ - NCT06455800Recruiting
Severe lung disease in childhood
This study looks at severe lung disease in children. It may help doctors better understand and treat these conditions.
OdenseAges 1 day–18 years - NCT05353946Recruiting
Rotational atherectomy elective vs emergency for heavily calcified blockages
This trial compares doing a special procedure (rotational atherectomy) before an emergency is needed versus using it as a rescue during a heart artery procedure. It is designed for people with very hard, calcified artery blockages and long-term kidney impairment, to see which approach works better and is safer.
MadridAges 18–100 - NCT06387875Recruiting
Community health study in Qianwan, Ningbo
This study is creating a health database of people living in Qianwan New District, Ningbo. Researchers will ask about your health and lifestyle, and follow up over time to learn about community well-being.
ShanghaiAges 18 years+ - NCT06524037Recruiting
Metabolic profiles and chronic disease study
This study looks at how your metabolic health (like blood sugar and cholesterol) relates to chronic diseases and cancer. If you are an adult who has already had a health screening, you may be able to join.
Chongqing, Chongqing MunicipalityAges 18–85 - NCT07451977Recruiting
Oxygen during a 6-minute walk test for lung disease
This trial tests whether adding extra oxygen during a 6-minute walk test helps people with chronic lung disease breathe better. It is for people with COPD or interstitial lung disease who have low oxygen levels, either during exercise or all the time.
Lumezzane, BresciaAges 18 years+ - NCT04844606RecruitingPhase 3
Mirikizumab for kids with ulcerative colitis or Crohn’s
This study checks whether continuing mirikizumab (a medicine that calms gut inflammation) helps children with ulcerative colitis or Crohn’s disease after prior study treatment. It aims to see if staying on the medicine is beneficial and safe over time.
San Francisco, CaliforniaAges 2–19 - NCT06502873Recruiting
Study of colon samples in IBD and healthy people
This study is gathering information from people with active Crohn's disease or ulcerative colitis, and from people without IBD. Researchers will look at samples from the colon to learn more about these conditions.
LiègeAges 18 years+ - NCT07114393Recruiting
Better imaging to guide complex heart artery procedures
This study looks at whether using advanced imaging inside the heart arteries during complex procedures leads to better outcomes compared to current standard practice. If you have had a complex angioplasty (PCI) and your data is in a national heart registry, you may be included.
Eindhoven, North BrabantAges 18 years+ - NCT07593352Recruiting
Kidney Health in Inflammatory Bowel Disease Patients
This study compares kidney function between people with inflammatory bowel disease (IBD) and those without it. Researchers want to understand if IBD affects the kidneys and why, which could help protect kidney health in IBD patients.
Warsaw, WarszawaAges 18–80 - NCT06038409Recruiting
Ketamine therapy for chronic conditions
This trial tests if ketamine can help people with long-term health issues. It aims to find new treatments for chronic conditions that haven't responded well to other therapies.
Helena, MontanaAges 18 years+ - NCT07491315Recruiting
Do ME/CFS patients react differently to exercise?
This study looks at whether people with ME/CFS have a different reaction to exercise compared to people with heart conditions who also feel tired. It involves filling out online questionnaires and may help doctors better understand ME/CFS.
MarseilleAges 18 years+ - NCT07330635Recruiting
Chronic wounds and blood circulation checkup
This study checks how well blood flows in the legs of people with and without chronic wounds or circulation problems. It may help doctors better understand and treat poor circulation.
TaipeiAges 20–95 - NCT02653079Recruiting
Blood testing and low-dose radiation for painful joint conditions
This study collects blood samples and treats certain painful joint/soft-tissue problems with low-dose local radiation therapy. It aims to understand disease features and how patients may respond to this treatment.
Erlangen, BavariaAges 18 years+ - NCT04802395Recruiting
KidneyIntelX check for people with diabetes and early kidney disease
This study looks at how well a kidney test tool called KidneyIntelX works in real-world care for people with type 2 diabetes and certain stages of kidney disease. It may help doctors use the tool to better understand kidney risk and guide next steps.
New York, New YorkAges 23 years+ - NCT07737236Recruiting
Ruscus study for symptom relief in chronic vein problems
This study tests a natural plant extract called Ruscus to see if it helps control symptoms of chronic venous insufficiency, a condition where leg veins have trouble moving blood back to the heart. It is for people who are already starting this treatment as part of their regular care.
Ankara, AnkaraAges 18–75
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,257 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.