Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06673498RecruitingPhase 2
Two drugs to raise platelets before surgery in liver disease
This trial tests two medications (lusutrombopag and recombinant human thrombopoietin) given together to raise platelet levels before a planned surgery in people with chronic liver disease. The goal is to reduce the need for platelet transfusions and make the procedure safer.
Fuyang, AnhuiAges 18 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Sun City, ArizonaAges 18 years+ - NCT07661940RecruitingPhase 2
SP16 for kidney protection during heart surgery
This trial tests a drug called SP16 to see if it can prevent acute kidney injury in people with chronic kidney disease who are having elective heart surgery with a heart-lung machine. It aims to help preserve kidney function after surgery.
Erlangen, BavariaAges 18 years+ - NCT07638176Recruiting
Better breathing support during lung surgery
This study tests whether adjusting breathing machine settings during lung surgery improves oxygen levels and recovery. If you're having lung surgery, this trial may help doctors keep you safer during the procedure.
SeoulAges 19–100 - NCT04588077RecruitingPhase 4
Two-dose vs three-dose hepatitis B vaccine for cirrhosis
This study compares giving the hepatitis B vaccine in 2 doses versus 3 doses for people with cirrhosis who do not yet have protection against hepatitis B. It may help your care team choose the schedule most likely to build lasting immunity.
Baltimore, MarylandAges 18 years+ - NCT07633145Recruiting
Lifestyle Changes to Lower Blood Pressure in Kidney Disease
This study tests whether lifestyle changes—like diet and exercise—can help lower blood pressure in Black adults with moderate kidney disease. It's designed specifically for people at higher risk of kidney problems, and the goal is to see if these changes can slow kidney disease progression and reduce heart disease risk.
Durham, North CarolinaAges 18 years+ - NCT07615985RecruitingPhase 1
Safety and Blood Levels of PMG1016 in Healthy Adults
This study tests a new experimental medicine called PMG1016 to see how safe it is and how it moves through the body in healthy volunteers. You'll receive a single dose and have your blood checked and heart monitored to make sure the medicine is well-tolerated.
Brisbane, QueenslandAges 18–55 - NCT06533254Recruiting
Study on behavioral AI to predict and increase peritoneal dialysis use
This trial uses behavioral AI to help predict and encourage use of peritoneal dialysis in patients with advanced chronic kidney disease (stages 4-5). It aims to understand what factors influence decision-making and improve access to this treatment option.
Dallas, TexasAges 18 years+ - NCT06713850Recruiting
Balloon treatment for leg artery blockages with calcium
This trial uses a special balloon (Shockwave IVL) to break up calcium in leg artery blockages, improving blood flow and reducing pain. It's for people with moderate to severe calcium buildup in the femoropopliteal artery.
Wuhan, HubeiAges 18 years+ - NCT06694012Recruiting
Ohtori Study Part 2 heart health
This study looks at heart and metabolic health in the general population. It helps researchers understand how to prevent conditions like diabetes and heart disease.
Sakai, OsakaAges 20 years+ - NCT07577817RecruitingEarly Phase 1
Safety Study of CTX001 in Healthy Adults
This early-stage study tests a new experimental drug called CTX001 in healthy volunteers to check if it is safe and well-tolerated. Researchers will also measure how your body processes the drug and how it affects certain blood markers.
Melbourne, VictoriaAges 18–55 - NCT06126016Recruiting
A study of Pacitol Inj. for dialysis patients with parathyroid issues
This study watches how well the drug Pacitol Inj. works and how safe it is in people on dialysis who have overactive parathyroid glands caused by kidney disease. It follows patients who are already prescribed this drug by their doctor.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT06274710Recruiting
Kidney health support trial for those at dialysis risk
This study tests a new care program to help people with chronic kidney disease (CKD) who have a higher risk of needing dialysis soon. It uses online tools to support you and your care team in managing your health.
Toronto, OntarioAges 18 years+ - NCT06576479Recruiting
Supplement study for kidney disease and weight loss
This study tests if a special drink can improve nutrition and quality of life in people with chronic kidney disease (CKD) who are not on dialysis. It is for those who have lost weight or have poor appetite.
Guadalajara, JaliscoAges 18–90 - NCT07547878Enrolling by invitationPhase 4
Starting four kidney-protective medicines together for type 2 diabetes
This study looks at whether starting four recommended medications all at once—instead of one by one—is safe and better for protecting the kidneys in people with type 2 diabetes and early kidney damage. You would receive all four medicines together and be closely monitored by the study team.
Temple, TexasAges 18–84 - NCT07536672Enrolling by invitation
Understanding Pain and Sexual Health in Chronic Pain
This study helps develop a questionnaire (survey) that measures how chronic pain affects sexual health and relationships. If you have long-term pain and a stable relationship, your feedback could help doctors better understand and support patients like you.
Kütahya, KütahyaAges 18 years+ - NCT06756009Recruiting
Eye scans to check liver disease and transplant outlook
This study uses advanced eye scans to see if your eyes can give clues about your chronic liver disease and how well you might do after a liver transplant. If you have advanced liver disease or cirrhosis, and are maybe waiting for a transplant, you may join.
Guangzhou, GuangdongAges 18 years+ - NCT07515794Enrolling by invitation
Long-term follow-up for transplant access study participants
This is a follow-up study for people who already participated in the STEPS research project about improving fairness in organ transplants. Researchers want to track how participants are doing over time and learn more about transplant outcomes.
Winston-Salem, North CarolinaAges 18–75 - NCT07499856Enrolling by invitation
Exercise and mindfulness during dialysis
This trial tests whether combining exercise with mindfulness (a mental relaxation technique) during dialysis sessions can improve well-being. You watch videos that guide you through exercises and mindfulness while receiving treatment.
Valencia, ValenciaAges 18 years+ - NCT07496177RecruitingPhase 2
HTD1801 for kidney function in diabetes and kidney disease
This trial tests whether a new drug, HTD1801, can protect or improve kidney function in people with type 2 diabetes and chronic kidney disease. It may help slow kidney damage and reduce protein in urine.
Weifang, ShandongAges 18–75 - NCT07481526Recruiting
Chronic kidney disease registry study
This study is collecting information from people with chronic kidney disease (CKD) to understand how the disease progresses over time. It does not test any new treatments, so you keep your usual care.
Anning, Yunnan - South RegionAges Any age - NCT07480057Recruiting
Bone health changes after liver transplant
This study tracks how liver transplantation affects your bone density and mineral metabolism. It aims to find changes early, which can help prevent fractures later.
New Delhi, National Capital Territory of DelhiAges 18 years+ - NCT07472842Recruiting
Study on outcomes for endometriosis in emergency care
This study follows women who come to a specific hospital's emergency department with known endometriosis or symptoms that might be endometriosis, to learn more about their health outcomes over time.
CréteilAges 18 years+ - NCT04814082Recruiting
Compare two knee implant types for walking and function
This study compares two designs of knee replacement implants to see how they affect walking, function, and outcomes after surgery. You may be randomly assigned to one of the implant types used for your specific, approved knee replacement.
Baltimore, MarylandAges 18–75
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,247 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.