Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,257 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06525857Recruiting
Observing body changes in long-term oxygen therapy
This study will observe how patients with chronic lung diseases change when they start long-term oxygen therapy at home. It aims to understand how the body adapts to oxygen treatment over time.
BernAges 18 years+ - NCT07333313Recruiting
Study of oral medicine and probiotics for kidney disease in diabetes
This trial tests if an oral medication that absorbs toxins plus probiotics can reduce inflammation and slow kidney damage in people with diabetes-related kidney disease (DKD). It may help those with mild to severe kidney function loss.
Taipei, TaiwanAges 20 years+ - NCT07684326RecruitingPhase 2/Phase 3
Can dapagliflozin help liver cirrhosis with fluid buildup? (Phase 2/3 randomized trial)
This trial tests a diabetes pill (dapagliflozin) to see if it helps people with liver cirrhosis and fluid buildup (ascites). The goal is to improve fluid balance and possibly reduce hospital stays.
GizaAges 18 years+ - NCT07419555Recruiting
Belgian study on lung function over time
This study tracks lung function over time in people with chronic lung disease. It helps doctors understand how lung health changes and may improve future care.
EdegemAges 18 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Peoria, ArizonaAges 18 years+ - NCT07741292RecruitingPhase 4
Kidney health study for older adults not on dialysis
This study tests whether a traditional Chinese medicine called Niaoduqing Granules can help improve kidney function in people over 60 with chronic kidney disease. It may offer a new way to manage the condition without dialysis.
Shanghai, Shanghai MunicipalityAges 61 years+ - NCT07725497RecruitingPhase 2
Luspatercept for anemia from chronic kidney disease
This trial tests a drug called luspatercept to see if it can raise hemoglobin levels in people with anemia caused by chronic kidney disease. It's for those whose current treatments aren't working well or who cannot use them.
Basking Ridge, New JerseyAges 18 years+ - NCT05106387Recruiting
Study follow-up for people who had a kidney transplant
This study follows adults who previously received vonsetamig in an earlier study and then got a kidney transplant while enrolled. It mainly looks at what happens after the transplant and helps doctors understand outcomes over time.
Los Angeles, CaliforniaAges 18–70 - NCT07712679Recruiting
Studying Kidney Scarring with FAPI PET/CT
This study uses a special PET/CT scan to look for scarring in the kidneys. The goal is to see if the scan can detect kidney fibrosis better than current methods.
Vienna, State of ViennaAges 18 years+ - NCT07317310Recruiting
Joint health and weight loss study for knee osteoarthritis patients
This trial tests a joint health program for people with knee osteoarthritis and a BMI of 27 or higher. The goal is to see if it can improve knee pain and help with weight management.
Taipei, TaiwanAges 18–75 - NCT03035747Recruiting
Registry for treatment of varicose veins
This study collects information about people who have varicose veins with abnormal backflow in the leg veins. It’s meant to track how treatments for chronic venous problems are working over time, which can help improve care for others in the future.
Saint PetersburgAges 18 years+ - NCT03055247RecruitingPhase 2
Try ibuprofen plus growth factor and stem-cell mobilizer for X-CGD
This trial tests a combination of medicines to help your body release (“mobilize”) stem cells for future treatment in people with X-linked chronic granulomatous disease (X-CGD). If it works well and is safe for you, it may make stem-cell collection easier and more successful.
Rome, LazioAges 18–45 - NCT03524222Recruiting
Home hospital care for adults after sudden illness
This trial tests whether certain adults can safely receive hospital-level care at home instead of staying in the hospital, using a home care team. It may help you recover in your own home if your condition fits their plan and you have support at home.
Boston, MassachusettsAges 18 years+ - NCT03595267Recruiting
Kidney health checks and care for Indigenous communities
This study offers kidney-related health screening and follow-up care for people in Indigenous communities. It’s designed to help check kidney health early using simple health measurements, and may help you get guidance sooner if anything looks off.
Calgary, AlbertaAges 10–80 - NCT03645486Recruiting
Gene therapy for chronic granulomatous disease (CGD)
This trial tests a lentiviral gene therapy to improve immune function in people with CGD, a condition where the body can’t fight certain infections well. It may help by addressing the underlying genetic problem, but it also requires a procedure to collect immune cells and special “conditioning” medicines beforehand.
Shenzhen, GuangdongAges Any age - NCT03929900Recruiting
Study follow-up for kidney disease in adults (non-dialysis)
This study follows adults with chronic kidney disease who are not on dialysis. It aims to better understand kidney health and test what care or monitoring might help over time.
Seoul, Jongno-guAges 45–79 - NCT04330729Recruiting
Aspirin effect on blood clotting in kidney disease
This study checks how aspirin (also called salicylate) affects how platelets work, which helps blood clot. It involves people with advanced chronic kidney disease who are treated with Aranesp, and it may help guide safer care.
RoskildeAges 18–85 - NCT04381143RecruitingPhase 4
Aspirin to prevent problems in people on dialysis
This trial studies whether taking aspirin can reduce heart and clot-related complications in adults receiving long-term dialysis. It may help by improving blood clotting behavior, but it also requires that aspirin is safe for you.
Fuzhou, FujianAges 18 years+ - NCT04500665RecruitingPhase 2
Colchicine for kidney-related heart inflammation
This Phase 2 trial tests whether colchicine can reduce inflammation and improve heart function in people with kidney disease and a certain type of heart problem. If you qualify, you’ll be closely monitored for side effects and lab changes.
Boston, MassachusettsAges 21–80 - NCT04522765Recruiting
Tracking daily blood pressure patterns in people at high heart risk
This study measures how your blood pressure changes across the day in people at higher risk of heart and blood vessel disease. It may help researchers understand why blood pressure patterns vary, which could guide better prevention or care.
EdinburghAges 18–90 - NCT04588077RecruitingPhase 4
Two-dose vs three-dose hepatitis B vaccine for cirrhosis
This study compares giving the hepatitis B vaccine in 2 doses versus 3 doses for people with cirrhosis who do not yet have protection against hepatitis B. It may help your care team choose the schedule most likely to build lasting immunity.
Baltimore, MarylandAges 18 years+ - NCT04592640RecruitingEarly Phase 1
Amniotic stem cell treatment for calciphylaxis
This early-phase study tests a stem cell therapy made from amniotic (placenta) tissue for people with calciphylaxis. If you qualify, the goal is to see whether this treatment is safe and potentially helpful for this rare, painful condition.
Nanjing, JiangsuAges 18–75 - NCT04626167RecruitingEarly Phase 1
Testing a bladder transplant done with a kidney transplant
This early-phase study is testing a combined bladder and kidney transplant approach for people whose bladder problems damage the kidneys. The goal is to see if this treatment can improve bladder and kidney outcomes and be done safely.
Rochester, MinnesotaAges 1–60 - NCT04759274Recruiting
Personalized water pill dosing support for kidney and fluid overload
This trial tests a decision-support tool to help your care team safely adjust water pills (“diuretics”) when you have kidney disease and fluid buildup. It may help reduce swelling by guiding dosing using your home weight and blood pressure.
Dallas, TexasAges 18 years+
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,257 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.