Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06396416RecruitingPhase 4
Obesity management after kidney transplant
This study tests whether a weight loss medication (semaglutide) can help manage obesity in people who have had a kidney transplant or are at high risk. It aims to improve health outcomes and prevent further kidney decline.
London, OntarioAges 18 years+ - NCT06397456Recruiting
Kidney education program for Black patients in the hospital
This study tests whether a special education and referral program helps Black patients with advanced kidney disease learn about their treatment options before they need dialysis or a transplant. If you join, you will get extra support while you're in the hospital.
Chicago, IllinoisAges 18–70 - NCT06387745Recruiting
Checking liver health with a new device
This study tests a new device called Hepatoscope that measures your liver health without a needle. It may be a good option if you have liver problems, diabetes, or metabolic syndrome and want a simple, noninvasive check.
Edegem, AntwerpAges 18–80 - NCT04500665RecruitingPhase 2
Colchicine for kidney-related heart inflammation
This Phase 2 trial tests whether colchicine can reduce inflammation and improve heart function in people with kidney disease and a certain type of heart problem. If you qualify, you’ll be closely monitored for side effects and lab changes.
Boston, MassachusettsAges 21–80 - NCT06330441Recruiting
Pancreatic cancer screening for high-risk groups
This study screens people at high risk for pancreatic cancer using imaging tests. It aims to catch cancer early in those with certain genetic conditions or strong family history.
BrnoAges 18 years+ - NCT06310967RecruitingPhase 1/Phase 2
Study of IG3018 for high uric acid with or without kidney disease
This trial tests a new medicine, IG3018, to lower high uric acid levels in people with or without chronic kidney disease. It aims to find the right dose and see if it's safe.
Botany, New South WalesAges 18–75 - NCT06300788Recruiting
Pyrophosphate study in children with kidney disease
This study looks at a natural chemical in the body called pyrophosphate (PPi) in children with chronic kidney disease. It aims to understand how kidney problems affect this chemical, which is important for bone health. The study needs kids with different kidney stages, including those on dialysis, with a transplant, or even healthy kids having surgery for comparison.
Nice, Alpes-MaritimesAges birth–18 years - NCT06306963Recruiting
Stomach blood vessel condition and digestion symptoms study
This study looks at people with a stomach condition called gastric antral vascular ectasia (GAVE) to understand how it affects digestion and causes symptoms. Researchers want to learn if stomach muscle function problems are common in this condition.
Rochester, MinnesotaAges 19 years+ - NCT06278207Recruiting
Finerenone in real-world diabetes and kidney disease
This study looks at how the medication finerenone works in everyday medical practice for people with type 2 diabetes and certain stages of chronic kidney disease. It aims to see how safe and effective the treatment is outside of a clinical trial setting.
Multiple Locations, New JerseyAges 18 years+ - NCT06128278RecruitingPhase 2
Equol supplement and blood vessel health in women
This study tests whether taking an Equol supplement (a soy-related compound) improves blood vessel function in postmenopausal women with and without chronic kidney disease (CKD). It could help women with or without early-stage CKD learn if this supplement supports heart health.
Aurora, ColoradoAges 50–69 - NCT06243068Enrolling by invitation
Supporting decisions about kidney care without dialysis
This study helps people with advanced chronic kidney disease explore their care options, including the choice to manage without dialysis. It provides support and information to help you and your family make a decision that fits your values.
San Francisco, CaliforniaAges 65 years+ - NCT06194591Recruiting
Ultrasound treatment for high blood pressure with kidney disease
This trial tests a new ultrasound treatment on the kidney arteries to see if it can safely lower blood pressure in people with high blood pressure and chronic kidney disease. It may help avoid more invasive procedures.
Lausanne, Canton of VaudAges 18–82 - NCT06181409Recruiting
New scans to detect liver disease complications
This study uses two types of scans (MRI and ultrasound) to check for high pressure in the veins of your liver. It may help doctors find problems earlier without invasive tests.
Montreal, QuebecAges 18 years+ - NCT06168604Recruiting
Pain communication toolkit for dementia caregivers
This trial tests a toolkit to help caregivers of adults with dementia and chronic pain better identify and communicate about their loved one's pain. You and the person you care for may join if you meet the listed requirements.
New York, New YorkAges 21 years+ - NCT06160635Recruiting
D-SOLVE: Study of Hepatitis D treatments
This trial is testing treatments for people with chronic hepatitis D, a serious liver infection. If you have antibodies to the hepatitis D virus (HDV), you may be able to join and help find better ways to manage this condition.
HanoverAges 18 years+ - NCT06153485Enrolling by invitation
Automated oxygen adjustment for home therapy
This trial is testing a smart system that automatically adjusts your home oxygen levels based on your needs. It's designed for people with stable lung conditions who already use home oxygen therapy.
Toronto, OntarioAges 18 years+ - NCT06110130RecruitingPhase 4
Empagliflozin for kidney health in African American veterans
This study is testing whether the drug empagliflozin (Jardiance) can help protect the kidneys of African American veterans who already have some kidney damage but do not have diabetes. The goal is to see if the drug can reduce damage at the cellular level.
Washington D.C., District of ColumbiaAges 19–90 - NCT06013865RecruitingPhase 4
Empagliflozin for kidney transplant recipients
This trial tests if empagliflozin, a diabetes medicine that also protects the kidneys, can help people who have received a kidney transplant. It may be an option if you have reduced kidney function or diabetes after transplant.
Hines, IllinoisAges 19 years+ - NCT05997875Recruiting
Learning about dialysis access options
This study tests a new way to teach people about hemodialysis and the access (the spot in your arm or leg where the dialysis machine connects). It is for people with advanced kidney disease who are considering hemodialysis and want to learn about their options for vascular access.
Baltimore, MarylandAges 18 years+ - NCT05981183Recruiting
Vagus nerve stimulation for chronic kidney disease
This study tests a device that gently stimulates a nerve in your ear to see if it can help people with chronic kidney disease (CKD). The device is non-invasive and may improve how your body handles kidney-related issues.
New York, New YorkAges 18–80 - NCT05997693RecruitingPhase 3
One month of blood thinners after heart bypass surgery
This trial tests whether taking just one month of two blood thinners after coronary artery bypass graft (CABG) surgery is safe and as effective as the standard longer course. It focuses on people having their first bypass surgery who receive at least one vein graft from the leg.
Englewood, New JerseyAges 18 years+ - NCT05880914Recruiting
Personalized treatment study for bone disease in kidney failure
This trial looks at a personalized approach to diagnosing and treating bone problems caused by long-term kidney disease. It may help by matching treatment plans to the type of bone turnover found in your tests or biopsy.
St Louis, MissouriAges 18 years+ - NCT05793138Enrolling by invitation
Care model for older adults on dialysis at home
This trial tests a geriatric (older-adult) care approach to support people age 55+ who receive dialysis while living in the community. It may help improve how care is coordinated for older adults, including those with mild to moderate memory or thinking problems.
Durham, North CarolinaAges 55 years+ - NCT05655325Recruiting
Exercise program to improve thinking in older adults with mild memory trouble
This study tests whether a supervised exercise plan can improve executive thinking (like planning and task control) in older adults with mild cognitive impairment. Researchers also look for brain changes using an MRI.
Washington D.C., District of ColumbiaAges 55 years+
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,247 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.