Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06863012Recruiting
Measuring liver pressure with endoscopy: a new method
This trial compares a newer, less invasive method (using an endoscope) to measure pressure in the liver's blood vessels with the standard technique. It may help people with liver disease or suspected cirrhosis better understand their condition.
BarcelonaAges 18–85 - NCT06840652Enrolling by invitation
Baclofen for alcohol withdrawal in liver disease
This trial tests if baclofen, a medicine for alcohol dependence, is safe and works for people with chronic liver disease who are actively drinking. It may help you stop drinking alcohol safely.
Sabadell, BarcelonaAges 18–75 - NCT06631820Recruiting
A study of epicatechin for muscle health in advanced kidney disease
This trial tests whether a natural supplement called epicatechin can improve muscle health in people with advanced chronic kidney disease (CKD). You may be able to join if you have low kidney function and are not planning to start dialysis or have a kidney transplant in the next 4 months.
Huddinge, Stockholm CountyAges 60 years+ - NCT06823115Enrolling by invitation
Worldwide study of kidney injury in newborns
This study looks at how common acute kidney injury is in newborns in the intensive care unit. It helps doctors understand which babies are at risk and how to prevent kidney problems.
Birmingham, AlabamaAges birth–2 weeks - NCT06802978Recruiting
Lipid test in diabetic and non-diabetic kidney patients
This study checks cholesterol and fat levels in the blood of people with chronic kidney disease, comparing those with and without diabetes. It aims to understand how kidney disease affects lipid profiles.
SohagAges 21 years+ - NCT06801886Enrolling by invitationPhase 3
Silymarin for better kidney transplant success
This trial tests if adding silymarin (a milk thistle extract) to standard anti-rejection medicines helps protect the new kidney from damage. It may improve how well the transplanted kidney works over time.
MartinAges Any age - NCT04819217Recruiting
Probiotics and a toxin binder to slow chronic kidney disease
This trial studies an oral product (a “uremic toxin” absorber) plus probiotics to help slow the progression of chronic kidney disease. It may help by lowering harmful gut-related substances that can build up when kidney function is reduced.
TaipeiAges 20 years+ - NCT06658782Recruiting
MRI vs ultrasound for liver cancer detection in high-risk people
This trial compares two types of scans to see which detects liver cancer better in people at high risk. You would receive either an MRI with contrast or an ultrasound every 6 months to monitor for liver cancer.
Oxford, OxonAges 18 years+ - NCT06642272RecruitingPhase 4
Comparing two diabetes drugs in real-world use
This trial compares two common diabetes medications, empagliflozin and dapagliflozin, to see which works better in everyday practice. It aims to find the best treatment option for patients with type 2 diabetes.
CopenhagenAges 18 years+ - NCT06624358Recruiting
Physical activity study for teens with chronic kidney disease
This study looks at physical activity in teens with chronic kidney disease (CKD) who are not yet on dialysis or have had a transplant. It aims to understand their current activity levels and how to help them stay active safely.
Philadelphia, PennsylvaniaAges 13–18 - NCT06607913Recruiting
Exercise after hospitalization for kidney patients
This study tests whether a personalized exercise program can help adults over 55 with chronic kidney disease regain strength and mobility after a hospital stay.
Aurora, ColoradoAges 55 years+ - NCT06592820Recruiting
Ultrasound stiffness test for fatty liver disease
This study uses a special ultrasound technique, called shear wave elastography, to measure liver stiffness during an endoscopic ultrasound (EUS) procedure. It aims to see how well this new method detects liver scarring (fibrosis) in people with fatty liver disease, compared to standard tests like FibroScan and liver biopsy.
Boston, MassachusettsAges 18 years+ - NCT06593392RecruitingPhase 2
Safety of difelikefalin for itching in teens on dialysis
This trial tests a drug called difelikefalin to see if it safely reduces moderate-to-severe itching in teenagers who are on hemodialysis. Itching is common in kidney disease, and this study aims to find a new treatment option.
ChengduAges 12–18 - NCT06595420Recruiting
Kidney health in people with cystic fibrosis on new treatments
This study looks at how the kidneys work in people with cystic fibrosis, especially those taking highly effective new treatments. It aims to understand kidney function in different groups, including those who are hospitalized frequently or rarely.
Birmingham, AlabamaAges 7 years+ - NCT06578078RecruitingPhase 3
Best heart failure care for older patients with kidney disease
This study tests the best way to manage heart failure in older adults who also have kidney problems and high potassium levels. It compares different treatment strategies to see which one is safest and most effective.
Alcorcón, MadridAges 70 years+ - NCT06578533RecruitingPhase 3
Keeping heart and kidney medications while controlling potassium
This trial tests a medication (SZC) that helps lower high potassium levels, so you can keep taking important heart and kidney drugs (RAASi/MRA). It is for people with heart failure and chronic kidney disease who have high potassium.
AlicanteAges 18 years+ - NCT06572215Recruiting
New ways to check kidney function in sickle cell patients
This study tests two new methods to measure how well your kidneys can handle extra work, called kidney reserve. It might help find early signs of kidney problems in people with sickle cell disease or those who have donated a kidney.
LondonAges 40 years+ - NCT06574425Enrolling by invitationPhase 4
Long-term high-flow hemoadsorption for dialysis patients
This study tests a long-term, high-flow hemoadsorption therapy for people on maintenance hemodialysis. It aims to see if the treatment can improve outcomes for those with uremia (built-up waste in the blood).
Beijing, Beijing MunicipalityAges 18 years+ - NCT06549725Recruiting
Lipidica software for pancreatic cancer screening
This trial tests a software that analyzes fats (lipids) in your blood to find pancreatic cancer early. You may join if you have pancreatic cancer that can be removed with surgery, or if you are at very high risk due to family history or certain gene mutations.
Prague, CzechiaAges 18 years+ - NCT06560801RecruitingPhase 4
Dapagliflozin for kidney health after transplant
This trial tests whether taking dapagliflozin (a drug often used for diabetes and heart health) can help improve kidney structure and blood flow in people who received a kidney transplant at least 9 months ago. It may benefit those whose kidney function is stable, regardless of whether they have diabetes.
Erlangen, BavariaAges 18–75 - NCT06458322Recruiting
Dialysis at home vs. in a center: quality of life study
This study compares the quality of life of people who start dialysis at home versus in a center. It aims to help patients and doctors choose the best option for each person's lifestyle and well-being.
Montreal, QuebecAges 18 years+ - NCT04759274Recruiting
Personalized water pill dosing support for kidney and fluid overload
This trial tests a decision-support tool to help your care team safely adjust water pills (“diuretics”) when you have kidney disease and fluid buildup. It may help reduce swelling by guiding dosing using your home weight and blood pressure.
Dallas, TexasAges 18 years+ - NCT06409624Recruiting
Biomarkers and kidney decline in pulmonary hypertension
This study looks at how certain blood markers (biomarkers) relate to kidney function decline in people with pulmonary hypertension. Participants will have blood and urine tests, and their kidney function will be tracked over time.
Bad Nauheim, HesseAges 18 years+ - NCT03055247RecruitingPhase 2
Try ibuprofen plus growth factor and stem-cell mobilizer for X-CGD
This trial tests a combination of medicines to help your body release (“mobilize”) stem cells for future treatment in people with X-linked chronic granulomatous disease (X-CGD). If it works well and is safe for you, it may make stem-cell collection easier and more successful.
Rome, LazioAges 18–45
Hear when a new Chronic Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,247 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.