Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,247 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07113743Enrolling by invitationPhase 1/Phase 2
Gene therapy for x-linked chronic granulomatous disease
This trial tests a new gene therapy for X-linked chronic granulomatous disease (CGD), a condition where the immune system cannot fight certain infections. The treatment uses your own blood stem cells, which are modified in the lab to help your body produce working immune cells.
Bethesda, MarylandAges 3–60 - NCT07105670Recruiting
Replacing high-protein foods in chronic kidney disease
This study looks at how replacing high-protein foods affects people with chronic kidney disease. If you join, you will eat a carefully controlled diet to help researchers understand if changing your protein intake can improve your kidney health.
West Lafayette, IndianaAges 40–70 - NCT06982079RecruitingPhase 3
SGLT2 inhibitors for advanced kidney disease
This trial tests whether SGLT2 inhibitor drugs can protect kidney function in people with advanced chronic kidney disease who are not yet on dialysis. It may help slow further kidney decline.
CairoAges 18 years+ - NCT07020104Recruiting
Salt and water in chronic kidney disease
This study looks at how salt builds up in the skin of people with chronic kidney disease. It involves different groups testing either sodium intake, sodium excretion, or water intake to see how these affect blood pressure and kidney function.
Amsterdam-Zuidoost, North HollandAges 18 years+ - NCT06326957Recruiting
Online program for chronic breathlessness
This trial tests an internet-based self-guided program to help adults with chronic breathlessness. It is designed for people who still feel short of breath despite treatment for conditions like COPD, lung disease, or cancer.
LondonAges 18–110 - NCT05942027RecruitingPhase 4
CoQ10 in early-to-moderate kidney disease with high urine protein
This study tests whether taking coenzyme Q10 can improve chronic kidney disease in adults with moderate kidney function and higher urine protein. It also looks at safety, especially for blood pressure and potassium levels.
Tanta, Capital of Gharbia Governorate.Ages 18 years+ - NCT05942053RecruitingPhase 4
Vitamin K2 for chronic kidney disease with high urine protein
This trial studies whether vitamin K2 can help people with chronic kidney disease (kidney damage that lasts months or longer), especially those with higher protein levels in the urine. It compares vitamin K2 use in a specific group and watches kidney-related health outcomes and safety.
Tanta, Capital of Gharbia Governorate.Ages 18 years+ - NCT06858319RecruitingPhase 3
Long-term study of zigakibart for IgA nephropathy
This study is for people with IgA nephropathy who completed a previous zigakibart study. It tests whether continuing treatment with zigakibart (given as a shot every two weeks) is safe and helpful over a longer period.
Denver, ColoradoAges 18–100 - NCT06841692Recruiting
Diuretic testing for moderate kidney disease
This study checks how well diuretics (water pills) work in people with moderate chronic kidney disease. It may help doctors understand how to better treat fluid buildup in patients.
Rotterdam, South HollandAges 18 years+ - NCT06725810RecruitingPhase 4
Enarodustat for anemia in chronic kidney disease (not on dialysis)
This trial tests enarodustat, a pill for anemia, in people with chronic kidney disease who are not on dialysis. It aims to see if it can safely raise hemoglobin levels.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06741904Enrolling by invitation
Predicting liver disease worsening without invasive tests
This study looks at new, non-invasive methods to predict when chronic liver disease might get worse. It could help you and your doctor catch problems early without needing a biopsy or other invasive procedures.
Guangzhou, GuangzhouAges 18–80 - NCT06738394Recruiting
Exercise study for older adults with kidney disease
This study tests whether a supervised exercise program can help older adults with chronic kidney disease improve their physical function and stay active. You have to be able to do exercise and not be on dialysis.
Winston-Salem, North CarolinaAges 65–100 - NCT06732349Recruiting
Urine Tests for Chronic Kidney Disease Stage 3
This study looks at new urine tests to help monitor chronic kidney disease (CKD) stage 3. The goal is to find better ways to track kidney health and potentially slow the disease.
Rotterdam, South HollandAges 18 years+ - NCT06717698RecruitingPhase 2
Testing a new medicine for kidney damage in chronic kidney disease
This study tests different doses of an investigational medicine (NNC0519-0130) to see if it can reduce kidney damage in people with chronic kidney disease. It may be an option for you if you have kidney impairment and either have or don't have type 2 diabetes.
San Dimas, CaliforniaAges 18 years+ - NCT06715735Recruiting
A health coaching program for metabolic syndrome with kidney disease
This trial tests if a personalized health coaching program can help people with metabolic syndrome and chronic kidney disease make lasting lifestyle changes. If you have both conditions and are not yet on dialysis, this program may help you manage your health.
Chengdu, SichuanAges 18 years+ - NCT06694558Recruiting
Monocytes in type 1 diabetes and kidney disease study
This study looks at immune cells (monocytes) in people with type 1 diabetes, with or without early kidney problems. Researchers want to understand how these cells differ between groups. You may be able to join if you have type 1 diabetes and use an insulin pump or injections along with a continuous glucose monitor (CGM).
Cleveland, OhioAges 18–65 - NCT06605378Recruiting
Antibody and cytokine study for people with CGD
This study is checking levels of antibodies and immune-signaling molecules (cytokines) in people with chronic granulomatous disease (CGD). It aims to better understand the immune system in CGD, which may help with future treatments.
Montgomery, AlabamaAges Any age - NCT06579612Recruiting
Personalized exercise support for chronic lung disease
This trial tests whether one-on-one guidance from a sports-health specialist can improve your well-being if you have a chronic lung condition like asthma, COPD, or sleep apnea and are already taking part in a lung rehabilitation program.
BrestAges 18–80 - NCT06527768Recruiting
Helping with metabolic syndrome and kidney disease through lifestyle changes
This study tests a program that uses WeChat to help people with metabolic syndrome and chronic kidney disease make healthy lifestyle changes. They want to see if this support can improve health and slow down kidney problems.
Chengdu, SichuanAges 18 years+ - NCT06523608Recruiting
Predicting liver problems in advanced chronic liver disease
This study looks at people with advanced chronic liver disease to find ways to predict when they might get worse or develop liver cancer. Researchers hope to use this information to prevent complications and improve care.
Münster, North Rhine-WestphaliaAges 18 years+ - NCT06324045Recruiting
Deprescribing medicines for kidney disease patients
This study looks at whether carefully reducing or stopping some medicines (deprescribing) can help people with advanced kidney disease. The goal is to improve quality of life and avoid side effects from unnecessary medications.
DohaAges 18 years+ - NCT06329622RecruitingPhase 3
Does Ketosteril help muscle loss in kidney disease?
This study tests whether a medicine called Ketosteril can improve muscle strength and function in people with moderate to severe chronic kidney disease (CKD) who also have sarcopenia (age-related muscle loss).
ShanghaiAges Any age - NCT06256991RecruitingPhase 4
Potassium management for kidney health
This study tests if careful potassium management can help people with chronic kidney disease (CKD) safely take higher doses of blood pressure medicines called ACE inhibitors or ARBs, which are known to protect the kidneys. You may be eligible if you have moderate to advanced CKD and are already on a moderate dose of one of these medications.
GroningenAges 18 years+ - NCT06202235Recruiting
Magnetic resonance imaging for chronic kidney disease
This trial uses a special MRI technique called multifrequency magnetic resonance elastography (MRE) to see if it can help evaluate chronic kidney disease. It may provide a non-invasive way to monitor kidney health without needing a biopsy.
Shenyang, LiaoningAges 18–65
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,247 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.