Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,256 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07222683Recruiting
How kidney transplant affects heart blood vessel health
This study looks at how receiving a kidney transplant changes the health of small blood vessels in the heart. It may help people with advanced kidney disease understand the benefits of transplant on their heart health.
Boston, MassachusettsAges 18 years+ - NCT07235059RecruitingPhase 1
Testing OJR520 in healthy people and those with chronic kidney disease
This study tests a new drug called OJR520 to see if it's safe and how the body processes it. It first tests healthy volunteers and then people with chronic kidney disease to understand the drug's effects.
Miami, FloridaAges 18–65 - NCT07239570RecruitingPhase 4
Using biomarkers to personalize kidney disease treatment
This study tests if matching treatments to your specific kidney disease markers can better protect your kidneys. It looks at how well Finerenone, Dapagliflozin, and Semaglutide work alone or in a sequence.
HerlevAges 18–75 - NCT01752738Recruiting
Study of gut microbial metabolites in chronic kidney disease
This trial studies how substances made by gut microbes travel in people with chronic kidney disease. You may be asked to have a planned colonoscopy so researchers can measure intestinal samples and better understand kidney disease.
Leuven, Vlaams BrabantAges 18–85 - NCT02411773RecruitingPhase 1
Test a nerve-blocking medicine in kidney disease
This Phase 1 study tests whether a medicine that reduces nerve signals (“sympatholysis”) is safe and how it affects people with chronic kidney disease. It may help researchers understand new ways to protect the kidneys, but the main goal here is safety.
Decatur, GeorgiaAges 18–75 - NCT02848131Enrolling by invitationPhase 2
Testing dasatinib and quercetin in diabetes-related kidney disease
This study tests whether two medicines (dasatinib and quercetin) can affect “cell aging” in people with chronic kidney disease related to diabetes. You may be asked to take pills for a short period and complete follow-up visits to measure how your body responds.
Jacksonville, FloridaAges 40–80 - NCT07405216RecruitingPhase 4
SGLT2 inhibitors for teens with early kidney disease
This trial tests whether a type of medicine called SGLT2 inhibitors can help teenagers with early-stage chronic kidney disease. It looks at how safe and effective these drugs are for slowing down kidney damage.
Aguascalientes, AguascalientesAges 14–18 - NCT07493642Recruiting
Video health program for chronic kidney disease patients
This trial tests whether watching educational videos about exercise and staying active can improve physical fitness for people with early to moderate chronic kidney disease. You can take part from home using a smartphone, tablet, or computer.
New Taipei City, Taishan DistrictAges 20 years+ - NCT07588854Recruiting
Liver Stiffness Testing and Biopsy for Chronic Liver Disease
This study compares two non-invasive ultrasound methods (EUS-SWQ and FibroScan) with liver biopsy to see how well they detect liver scarring in patients with chronic liver disease. The goal is to improve how doctors diagnose and monitor liver damage from conditions like hepatitis B and fatty liver disease.
ShanghaiAges 18–80 - NCT07541495Enrolling by invitation
Mindfulness Training for Adults With Chronic Kidney Disease
This study tests whether a mindfulness program (guided meditation and breathing exercises delivered on a smartphone) can help people manage chronic kidney disease and improve their quality of life. You'll use a study-provided app to practice mindfulness several times a week for 8 weeks.
New Haven, ConnecticutAges 18–80 - NCT07113743Enrolling by invitationPhase 1/Phase 2
Gene therapy for X-linked chronic granulomatous disease
This trial tests a new gene therapy for X-linked chronic granulomatous disease (CGD), a condition that causes severe infections. The treatment uses your own stem cells that are modified to fight the disease, aiming to reduce infections and inflammation.
Bethesda, MarylandAges 3–60 - NCT05514184Enrolling by invitation
Diet coaching for diabetes and kidney disease to delay dialysis
This study tests a plant-focused diet plan to help people with diabetes and moderately to severely reduced kidney function avoid or delay needing dialysis. You would get diet instructions based on your random group and have several follow-up visits and check-ins over 6 months.
Orange, CaliforniaAges 18 years+ - NCT06314503Recruiting
Safety study of a new peritoneal dialysis device for kidney patients
This trial tests a new device called WEAKID for people on peritoneal dialysis. It aims to see if the device is safe to use. Participants must have been on PD for at least 3 months and have no recent infections or catheter problems.
Modena, ModenaAges 18 years+ - NCT05189925RecruitingPhase 1
Correcting a missing immune enzyme using an mRNA cell therapy
This early-phase trial tests whether an mRNA-based treatment can correct a key immune problem in people with chronic granulomatous disease (CGD). It may help your immune cells work better against infections, but this is mainly to check safety and early signs of benefit.
Bethesda, MarylandAges 18–75 - NCT07743021Recruiting
Blood sample study for better health screening
This study collects blood samples and health information over time to improve early detection of diseases. It may help researchers find ways to prevent serious conditions.
BalatonfüredAges 40 years+ - NCT03619850RecruitingPhase 3
Ferumoxytol vs iron sucrose for child kidney anemia
This study compares two IV iron treatments—ferumoxytol and iron sucrose—to treat iron deficiency anemia in children with chronic kidney disease. It aims to see which option works better and is safe, and also to learn how each medicine behaves in the body.
Hollywood, FloridaAges 2–17 - NCT04404114Recruiting
Shear wave ultrasound to tell acute from chronic kidney disease
This study checks whether a special ultrasound can help tell whether kidney problems started suddenly (acute) or have been present longer (chronic). It may help doctors choose the right next steps faster in the emergency room.
TaipeiAges 20 years+ - NCT06286748Recruiting
Beetroot drink and exercise for kidney disease
This study tests if drinking beetroot extract along with a structured exercise program can help people with chronic kidney disease. It looks at whether this combination can improve health and delay the need for more advanced treatments.
Rio de Janeiro, Rio de JaneiroAges 18–65 - NCT06434753RecruitingPhase 3
Zinc supplements for stable advanced liver disease
This trial tests whether taking zinc supplements can improve the outlook for people with a certain type of advanced liver disease that is still stable (no major complications). If you have compensated advanced chronic liver disease and meet the criteria, you might be able to join.
BarcelonaAges 18–80 - NCT06551311Recruiting
Cycling exercise for chronic kidney disease
This study tests whether a special type of cycling exercise (eccentric cycling) is safe and helpful for people with moderate to severe chronic kidney disease (CKD) or who are on dialysis. The goal is to improve fitness and overall health.
Tainan, TaiwanAges 55–85 - NCT06960304Recruiting
Exercise program to help kidney patients' fistula work better
This trial tests if structured exercises can help the new blood vessel connection (AVF) in your arm mature properly for dialysis. It may improve your fistula's success and reduce complications.
Coimbra, Coimbra DistrictAges 18 years+ - NCT06674031Recruiting
Survey on heart risk knowledge in kidney disease
This study aims to understand how much people with chronic kidney disease know about heart disease risk factors. It involves a simple questionnaire (no drugs or procedures) to help improve patient education.
AnkaraAges 18–65 - NCT06721143RecruitingPhase 1/Phase 2
Study of AION-301 for chronic kidney disease
This trial tests an experimental drug called AION-301 for people with chronic kidney disease (CKD). The goal is to see if it's safe and may help slow kidney decline. It's given by IV infusion and compared to a placebo (inactive infusion).
Miami, FloridaAges 35–75 - NCT06752577Recruiting
Stem cell treatment for chronic kidney disease safety study
This study tests whether a single infusion of stem cells from bone marrow is safe for people with chronic kidney disease (CKD). It aims to see if this treatment can help slow kidney function loss.
Jacksonville, FloridaAges 18 years+
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,256 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.