Clinical trials
Chronic Liver Disease and Cirrhosis clinical trials
Below are recruiting chronic liver disease and cirrhosis clinical trials, each written for real people, not researchers. We’re tracking 199 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06432582Recruiting
Liver disease blood marker study for people with stiff livers
This study looks at whether certain micro-RNA levels in your blood can help predict how your chronic liver disease is progressing. It is for people who already have some liver stiffness (measured by a special ultrasound) and are being treated at the University Hospital St. Pölten.
Sankt Pölten, Lower AustriaAges 18 years+ - NCT07270809Recruiting
Chronic liver disease with organ failure: early outcomes study
This study follows patients with chronic liver disease who are hospitalized non-electively for organ failure, to understand the course of illness and outcomes over six months. It may help doctors improve care for similar patients.
New Delhi, National Capital Territory of DelhiAges 18–70 - NCT06493799RecruitingPhase 3
Injectable placenta extract for fatty liver disease
This trial tests an injectable medication made from human placenta to see if it can improve liver health in people with fatty liver disease (from alcohol or other causes). It may help lower liver enzyme levels and reduce liver damage.
Yongin-siAges 19–70 - NCT06463366Recruiting
Using MRI to better diagnose liver fat, inflammation, and scarring
This study uses advanced MRI scans to get a clearer picture of liver fat, inflammation, and scarring in people with chronic liver disease. It aims to help doctors diagnose and understand liver problems better.
Shenyang, LiaoningAges 18–75 - NCT06318949Recruiting
Albumin changes as early signs of chronic liver disease
This study is looking at whether changes in a protein called albumin can help find liver disease earlier. It is for people who have some liver scarring but no serious complications.
AngersAges 18 years+ - NCT07685353Recruiting
Genes and graft fat after liver transplant study
This study looks at how genetic differences between liver donors and recipients affect fat buildup in the new liver after transplantation. It may help doctors understand why some transplanted livers develop steatosis (fatty liver) after the surgery.
New DelhiAges 18 years+ - NCT06741904Enrolling by invitation
Predicting liver disease worsening without invasive tests
This study looks at new, non-invasive methods to predict when chronic liver disease might get worse. It could help you and your doctor catch problems early without needing a biopsy or other invasive procedures.
Guangzhou, GuangzhouAges 18–80 - NCT07715500Recruiting
MRI of Bile Ducts in Living Liver Donors
This study uses an MRI scan to look at the bile ducts in healthy people who want to donate part of their liver. The goal is to see if the scan can help predict and prevent bile duct problems for the person receiving the liver.
New DelhiAges 18–55 - NCT07480057Recruiting
Bone health changes after liver transplant
This study tracks how liver transplantation affects your bone density and mineral metabolism. It aims to find changes early, which can help prevent fractures later.
New Delhi, National Capital Territory of DelhiAges 18 years+ - NCT07268196Recruiting
How a liver transplant affects sexual function
This study looks at how a liver transplant affects a person's sex life and sexual function. It includes married men who either are waiting for a transplant or have already had one with a healthy working liver.
New Delhi, National Capital Territory of DelhiAges 18–60 - NCT05744713Enrolling by invitation
Study of adults with long-term liver disease using health records
This observational study looks at adults with chronic liver disease (including cirrhosis) to better understand how people are managed and how they feel over time. Because it does not change your treatment, it may help researchers improve care and patient support.
Los Angeles, CaliforniaAges 18 years+ - NCT07042308Recruiting
Study of advanced chronic liver disease over time
This study follows people with advanced chronic liver disease to understand how their condition changes over time. If you have cirrhosis or high liver stiffness, you may be able to join to help researchers track the disease and learn more about it.
Hong KongAges 18 years+ - NCT05045482RecruitingPhase 1
Study drug in people with cirrhosis from blocked bile flow
This Phase 1 trial studies how saroglitazar magnesium works in people with liver scarring (cirrhosis) caused by a bile-flow problem. It helps doctors understand safety and how the body handles the medicine in this specific liver condition.
Indianapolis, IndianaAges 18–80 - NCT07544524Recruiting
Plant-Based Diet for Kidney Disease in Asian Adults
This study tests whether eating mostly plants (with some animal products) can safely help people with moderate kidney disease. Researchers will compare this diet to a standard kidney-friendly diet and see how it affects kidney function and overall health.
SingaporeAges 21–79 - NCT06514300Enrolling by invitation
Study of muscle fat in fatty liver disease
This study looks at how fat in the muscles may affect liver disease in people with fatty liver and related conditions like obesity or diabetes. It aims to better understand the connection between muscle fat and liver health.
BrusselsAges 18–75 - NCT07191886Recruiting
Managing liver disease: what matters to you?
This study asks people with liver disease about their needs and concerns during regular clinic visits. Your answers may help doctors improve care for others.
Indianapolis, IndianaAges 18 years+ - NCT03773887Recruiting
Study of liver inflammation and healing in alcohol-related liver disease
This study compares patterns of liver inflammation and the liver’s healing ability in people with alcohol-related liver disease, using blood tests and (in most cases) a liver tissue sample. It may help doctors better understand what is happening in the liver and how it may recover.
LilleAges 18–70 - NCT04578301Recruiting
Predicting who develops serious liver worsening after surgery
This study looks at your liver health before and after surgery to predict the risk of “acute-on-chronic liver failure,” which means a sudden worsening of liver function on top of an existing liver condition. If you qualify, your doctors may use study data to better identify who needs closer monitoring after surgery.
BonnAges 18 years+ - NCT04588077RecruitingPhase 4
Two-dose vs three-dose hepatitis B vaccine for cirrhosis
This study compares giving the hepatitis B vaccine in 2 doses versus 3 doses for people with cirrhosis who do not yet have protection against hepatitis B. It may help your care team choose the schedule most likely to build lasting immunity.
Baltimore, MarylandAges 18 years+ - NCT04613921Recruiting
Liver transplant study for severe worsening liver failure
This study looks at when liver transplant is offered and what outcomes happen in people with cirrhosis who have severe “acute-on-chronic” worsening. It may help doctors decide which patients benefit most from transplant and improve care after listing or not listing.
Los Angeles, CaliforniaAges 18–80 - NCT04690972Recruiting
Collection of blood and tissue samples for liver disease research
This study builds a research library of biological samples (like tissue and blood) from people with chronic liver disease. It aims to create better lab and preclinical models of tumors and long-term liver problems, which may help future treatments.
StrasbourgAges 18 years+ - NCT05095714Recruiting
Fast MRI for close monitoring of high-risk liver cancer
This trial studies a faster MRI scan to help track early liver cancer in people who have cirrhosis and are considered high risk. It may improve how often and how well doctors can look for changes without using longer imaging sessions.
BondyAges 18 years+ - NCT05205954Recruiting
Home hospital care for adults with advanced liver disease
This pilot study tests whether a “home hospital” program can safely care for people with advanced liver disease after they are admitted to the hospital. It may reduce time in the hospital while still treating serious complications like fluid buildup, breathing fluid, or confusion from liver disease.
Boston, MassachusettsAges 18 years+ - NCT05475015Recruiting
3D MRI scan to assess liver scarring and pressure
This study tests whether a special 3D MRI scan (3D-MRE) can measure liver scarring and the high pressure in the liver called portal hypertension. It may help your team use imaging to understand how severe your liver disease is, especially when a pressure test (HVPG) is being considered.
Shenyang, LiaoningAges 18–75
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Common questions
- Are there clinical trials for chronic liver disease and cirrhosis?
- Yes. Clin2 currently lists 199 recruiting chronic liver disease and cirrhosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic liver disease and cirrhosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic liver disease and cirrhosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.