Clinical trials
Chronic Medical Conditions clinical trials
Below are recruiting chronic medical conditions clinical trials, each written for real people, not researchers. We’re tracking 206 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07368946Recruiting
Phosphate study for people with kidney disease
This study looks at how the body handles phosphate in people with chronic kidney disease. It may help researchers understand how to better manage phosphate levels to improve health.
Dallas, TexasAges 18 years+ - NCT06350786Recruiting
Using a placebo to help reduce opioid pain medication
This trial tests whether a special placebo pill, given with your knowledge, can help you reduce your opioid pain medication. You'll work with your own doctor to safely lower your dose while taking the placebo.
Zurich, Canton of ZurichAges 18 years+ - NCT07304076Recruiting
JHG002 Injection for Chronic Low Back Pain
This study tests if JHG002 injections (made from human placenta) are safe and effective for treating chronic low back pain. It may help people who have had low back pain for at least 6 months and rate their pain as a 5 or higher on a 0–10 scale.
Seoul, Gangdong-guAges 19–70 - NCT06347796Recruiting
Embolization vs surgery for chronic subdural hematoma
This trial compares a newer, less invasive treatment (embolization) with traditional surgery to treat chronic subdural hematoma (a slow bleed on the brain). It aims to see which approach works better and has fewer side effects.
Phoenix, ArizonaAges 40–90 - NCT05899582Recruiting
Heart-bypass–like brain surgery for artery blockage patients
This trial studies whether a special bypass surgery can improve symptoms in people with a long-term (chronic) blockage of the middle brain artery. It aims to improve brain blood flow and reduce future stroke risk in the right patients.
BeijingAges 18–65 - NCT06083480RecruitingPhase 4
Reducing stress to prevent long-term pain after knee replacement
This trial tests if lowering oxidative stress (damage from natural body processes) during knee replacement surgery can prevent chronic pain afterward. It may help people with osteoarthritis who have moderate to severe pain before surgery.
Nashville, TennesseeAges 50 years+ - NCT07496177RecruitingPhase 2
HTD1801 for kidney function in diabetes and kidney disease
This trial tests whether a new drug, HTD1801, can protect or improve kidney function in people with type 2 diabetes and chronic kidney disease. It may help slow kidney damage and reduce protein in urine.
Weifang, ShandongAges 18–75 - NCT07337785RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a new kind of cell therapy (UCAR-T) that targets CD19 and BCMA proteins on immune cells. It is for people with certain neurological autoimmune diseases like multiple sclerosis, myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, or autoimmune encephalitis who have not responded well to standard treatments.
Wuhan, HubeiAges 18–70 - NCT07287423Recruiting
A study of a new pacemaker system for heart rhythm problems
This trial tests a new pacemaker system for people who need a pacemaker for a slow or irregular heartbeat. It aims to see if the system is safe and works well.
PragueAges 18 years+ - NCT06742931Recruiting
Balloon vs stent for heart artery blockages in high bleeding risk patients
This trial compares a drug-coated balloon (medicated balloon) to a drug-eluting stent (medicated mesh tube) for treating new blockages in heart arteries. It is designed for patients with a high risk of bleeding who have completed a short course of anti-clotting medication and have been event-free for at least one year.
AnsanAges 19 years+ - NCT06220721Recruiting
Preventing long-term high blood pressure after preeclampsia
This trial is testing a medication called nifedipine (a long-acting blood pressure pill) to see if it can help lower the risk of long-term high blood pressure and improve blood vessel health after a pregnancy complication like preeclampsia. It is for women who have just given birth and are still in the hospital.
Chicago, IllinoisAges 18 years+ - NCT07767370RecruitingEarly Phase 1
Two experimental drugs for chronic inflammatory diarrhea
This study tests two experimental capsules, ND-12 and H-6, given together to adults with long-term diarrhea caused by inflammation in the gut, such as active ulcerative colitis. It aims to see if the combination is safe and helps reduce diarrhea and inflammation.
Nanjing, JiangsuAges 18–75 - NCT05896800Recruiting
Inhaled nitric oxide for moderate to severe COPD symptoms
This study tests whether inhaled nitric oxide gas can improve outcomes in people with moderate-to-severe chronic obstructive pulmonary disease (COPD). It may help reduce breathing problems by targeting how airways and blood vessels respond in the lungs.
Nanjing, JiangsuAges 40–75 - NCT06413524Recruiting
Vibration exercises for people with COPD
This trial tests if different types of vibration exercises can help people with COPD (a chronic lung disease). It may be a good fit if you have severe COPD or have had recent flare-ups, are not already exercising regularly, and are willing to try a new therapy.
Taipei, Wenshan DistAges 40–99 - NCT07358195RecruitingEarly Phase 1
Combined stem cell and kidney transplant from a relative
This trial tests a combined transplant of blood-forming stem cells and a kidney from the same family member. It aims to help people with both advanced kidney failure and a blood cancer by potentially reducing the need for lifelong anti-rejection medicines.
Boston, MassachusettsAges 18–70 - NCT06859060Recruiting
Improving health for people with serious mental illness
This study helps people with serious mental illness like schizophrenia or bipolar disorder who also have chronic health conditions (e.g., diabetes, overweight) get better overall care. It focuses on improving health and wellness through preventive medical care in Puerto Rico.
Mayagüez, Puerto RicoAges 21 years+ - NCT07309367Recruiting
Web-based advance care planning for dialysis patients
This trial tests a web-based program called 'My Voice' that helps people on dialysis plan ahead for their future care. It's for patients in Singapore who have advanced kidney failure and certain health challenges, and it also involves a family caregiver.
SingaporeAges 21 years+ - NCT06621264Recruiting
Exercise study to improve walking in kidney and artery disease
This trial tests whether a supervised exercise program can help people with chronic kidney disease and peripheral artery disease walk better and feel stronger. It aims to improve mobility and quality of life.
Ferrara, ItalyAges 18–80 - NCT07325942Recruiting
Low vs high volume high-intensity interval training for heart failure
This study compares two different types of high-intensity interval exercise programs (one shorter, one longer) in people with chronic heart failure. It aims to see which program improves heart health and daily function more.
Cairo, Giza GovernorateAges 18 years+ - NCT07153939Recruiting
Study of a new device to create dialysis access
This trial tests a new device called the Velocity pAVF System that creates a connection between a vein and artery in your arm for hemodialysis. If you need dialysis now or within the next 6 months, this could be a new option for you.
Dothan, AlabamaAges 18–80 - NCT07022197RecruitingPhase 1/Phase 2
BAFF-R CAR T cells for severe nerve and immune diseases
This trial tests a new treatment using your own immune cells (called BAFF-R CAR T cells) for people with severe nerve and immune diseases that have not improved with standard medicines. These cells are designed to target and destroy certain immune cells that may be causing your illness.
Tianjin, Tianjin MunicipalityAges 18–60 - NCT07021495Recruiting
Skin disease study to improve treatment choices
This study looks at different skin diseases to find markers that can help guide treatment. It tests new treatments for several conditions like eczema, psoriasis, and lupus, with the goal of personalizing care.
Nijmegen, GelderlandAges 18 years+ - NCT05584761RecruitingPhase 1/Phase 2
Cord blood stem cells plus azacitidine for advanced blood cancers
This trial tests whether adding donated cord blood stem cells to azacitidine can improve outcomes for people with advanced MDS, CMML-2, or a certain type of AML. It may help by giving the treatment a stronger chance to control abnormal blood-forming cells.
Nanjing, JiangsuAges 18–80 - NCT07588438RecruitingPhase 4
Tirzepatide effectiveness and safety for diabetes and weight loss in Paraguay
This study tests how well and safely tirzepatide (a new injectable medication) works in real-world conditions for people with type 2 diabetes or obesity in Paraguay. The medication helps lower blood sugar and reduce weight.
AsunciónAges 18–70
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Common questions
- Are there clinical trials for chronic medical conditions?
- Yes. Clin2 currently lists 206 recruiting chronic medical conditions studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic medical conditions trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic medical conditions trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.