Clinical trials
Chronic Obstructive Pulmonary Disease Severe clinical trials
Below are recruiting chronic obstructive pulmonary disease severe clinical trials, each written for real people, not researchers. We’re tracking 212 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07351734RecruitingPhase 2
Testing JKN2403 for COPD: a new treatment option
This study tests an experimental drug called JKN2403 for people with moderate to severe COPD. It aims to see if the drug can reduce flare-ups and improve breathing compared to a placebo (a dummy pill).
Guangzhou, GuangdongAges 40–80 - NCT07339280Enrolling by invitation
Probiotics for COPD: symptoms, lungs, and inflammation
This study tests whether taking a probiotic can improve symptoms, lung function, and inflammation in people with COPD. It is for adults with stable COPD who have not had a flare-up or treatment change in the last two months.
KarlovacAges 18 years+ - NCT07319039Recruiting
Brain scan study of breathlessness in cancer, COPD, and heart failure
This study uses a brain scan (fMRI) to learn how the brain processes shortness of breath in people with advanced heart failure, COPD, or lung cancer. It aims to help doctors better understand and treat breathlessness.
Geneva, Canton of GenevaAges 18 years+ - NCT07307781Recruiting
Study of COPD patients with frequent flare-ups in Moscow
This study tests a new treatment for people with COPD who still have frequent flare-ups despite using two maintenance inhalers. It aims to see if the study medicine can reduce these flare-ups.
MoscowAges 18–100 - NCT07293429Recruiting
Posture and breathing training for COPD with forward head posture
This study tests a program that combines posture correction and breathing muscle exercises for people with COPD who also have a forward head posture. It aims to improve breathing and reduce shortness of breath.
LahoreAges 40–60 - NCT07288554RecruitingPhase 1
Study of BBT002 for healthy people and COPD patients
This trial tests an experimental drug called BBT002 in healthy volunteers and people with chronic obstructive pulmonary disease (COPD), a lung condition that makes breathing hard. It aims to see if the drug is safe and how the body processes it.
Hefei, AnhuiAges 18–75 - NCT07292714RecruitingPhase 2
Testing 9MW1911 for people with moderate to severe COPD
This trial tests a new medication called 9MW1911 to see if it can help people with moderate to severe COPD who have had recent flare-ups. It is for current or former smokers ages 40 to 75 who are already on standard COPD treatments.
Chizhou, AnhuiAges 40–75 - NCT07285122RecruitingPhase 1
Inhaled study drug for healthy smokers and people with COPD
This study tests an inhaled medication called RB042 in healthy adults, healthy smokers, and people with COPD. It aims to see how the drug works in the body and whether it is safe, which could help in developing a new treatment for COPD.
Nedlands, Western AustraliaAges 18–80 - NCT07285642Recruiting
Oxygen levels in muscles and brain in COPD patients
This study measures oxygen levels in your brain and leg muscles during exercise to understand how COPD affects them.
IstanbulAges 40–70 - NCT07261293Recruiting
Blood flow restriction exercise for COPD patients
This study tests whether adding mild blood flow restriction to aerobic exercise can improve lung function, exercise capacity, and inflammation in people with stable COPD. You would exercise on a bike or treadmill while wearing soft cuffs on your legs to lightly restrict blood flow.
IstanbulAges 40–80 - NCT07259174Recruiting
Ultrasound for diaphragm in COPD flare-ups
This study uses ultrasound to measure how well your diaphragm muscle works during a COPD flare-up. The goal is to see if this measurement can help predict how you will recover.
Zwolle, OverijsselAges 18 years+ - NCT05553223Recruiting
Very small activity doses for COPD symptoms
This study tests whether “micro-doses” of physical activity (short, small amounts) can help people with COPD. It aims to see if these small activity bursts are safe and beneficial for people who have stable COPD.
Kelowna, British ColumbiaAges Any age - NCT06915740Recruiting
Virtual Pulmonary Rehab for COPD Patients
This study tests a virtual (online) pulmonary rehabilitation program for people with COPD. If you join, you will participate in exercises and education from home, with remote support from the study team.
Turku, Southwest FinlandAges 18 years+ - NCT07212439Recruiting
Monitoring coughs to detect worsening COPD early
This study tests if monitoring your cough sounds can help detect a sudden worsening of COPD (a lung condition) sooner. It aims to find early warning signs so you can get treatment faster.
Pamplona, NavarreAges 18 years+ - NCT06629675Recruiting
Personalized music to boost walking in COPD
This study tests whether a personalized music program can help people with COPD walk more and feel better. The music changes based on your walking speed to keep you motivated during a pulmonary rehab program.
Leicester, LeicestershireAges 18 years+ - NCT07195838Recruiting
Mindful breathing for people with COPD
This study tests a mindful breathing program for people with COPD. It aims to help reduce stress and improve breathing. Participants use a smartphone or tablet to take part from home.
Hong KongAges 50–80 - NCT07190222RecruitingPhase 3
New medicine for COPD with frequent flare-ups
This study tests a new medicine called Lunsekimig for people with COPD that has frequent flare-ups and high eosinophil levels (a sign of inflammation). It aims to see if it can help control symptoms better than a placebo (a dummy treatment).
Birmingham, AlabamaAges 40–80 - NCT07190209RecruitingPhase 3
Testing lunsekimig for COPD with frequent flare-ups
This trial tests a new medicine called lunsekimig for people with COPD that still causes flare-ups despite standard treatment. It focuses on people with higher blood eosinophils (a type of white blood cell). If you smoke or used to smoke and have had at least 2 moderate or 1 severe flare-up in the past year, this study may be an option.
Chandler, ArizonaAges 40–80 - NCT07192016RecruitingPhase 4
MRI study of triple inhaler for COPD with breathlessness
This study uses a special MRI scan to see how well a single triple inhaler works for people with COPD who have moderate to severe shortness of breath or feel their health is not good. It compares two groups: those with a low risk of flare-ups and those with a high risk, to find out if the treatment helps both groups.
London, OntarioAges 50–85 - NCT07177976Recruiting
Comparing two breathing exercises for COPD
This study compares two breathing techniques—Pilates breathing and pursed lip breathing—to see which one improves chest expansion and peak expiratory flow rate (how fast you can blow air out) in people with mild COPD.
RawalpindiAges 40–64 - NCT07177339RecruitingPhase 3
Testing depemokimab for COPD with type 2 inflammation
This study tests an early treatment called depemokimab for people with moderate to severe COPD who have a type of inflammation linked to high eosinophils. It aims to reduce flare-ups and improve breathing.
Newport Beach, CaliforniaAges 40–75 - NCT06952881Recruiting
Studying COPD types and treatable traits
This study looks at different forms of COPD to find better ways to treat them. It may help you understand your own condition and receive more personalized care.
Hong KongAges 40 years+ - NCT07140328RecruitingPhase 2
Testing a new inhaler for COPD symptoms
This trial tests two forms of a new medication (HSK39004) in people with COPD. The goal is to see if they help improve breathing and are safe. Eligible participants must be between 40 and 80, have moderate to severe COPD, and be able to stop other COPD treatments during the study.
Nanchang, JiangsuAges 40–80 - NCT07118306Recruiting
COPD flare-up follow-up study
This study is for people with COPD who go to the emergency room for a moderate or severe flare-up. It looks at how they are doing after their visit and whether their current inhaler treatment is working well.
Park Ridge, IllinoisAges 40 years+
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Common questions
- Are there clinical trials for chronic obstructive pulmonary disease severe?
- Yes. Clin2 currently lists 212 recruiting chronic obstructive pulmonary disease severe studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic obstructive pulmonary disease severe trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic obstructive pulmonary disease severe trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.