Clinical trials
Chronic Obstructive Pulmonary Disease Severe clinical trials
Below are recruiting chronic obstructive pulmonary disease severe clinical trials, each written for real people, not researchers. We’re tracking 197 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07602192Recruiting
Chest Imaging and Blood Tests to Distinguish Asthma From COPD
This study uses chest CT scans and blood tests to better tell asthma and COPD apart and predict which treatments will work best for you. The goal is to help doctors diagnose and treat these lung conditions more accurately.
Seoul, Dongjak-guAges 19 years+ - NCT07474220Recruiting
Study of SLC25A48 in COPD
This study measures a protein called SLC25A48 in people with COPD (a lung condition that makes breathing hard) and in healthy people to learn if it plays a role in the disease.
New Taipei CityAges 18 years+ - NCT06714721Recruiting
Magnetic diaphragm stimulation for COPD
This study tests if magnetic stimulation of the diaphragm muscle can help people with COPD breathe better. If you have had COPD for at least 6 months, are over 18, and can answer questionnaires, you may be eligible.
AnkaraAges 18 years+ - NCT06717659Recruiting
Probiotics for lung rehab in COPD patients
This trial tests if adding probiotics (healthy bacteria you take as a supplement) to your regular lung rehab program helps people with COPD breathe better and feel stronger.
New Taipei CityAges 18 years+ - NCT06724315Recruiting
Studying severe COPD in Brazil
This study follows people with severe or very severe COPD to learn more about their health over time. You may qualify if your COPD causes many symptoms or frequent flare-ups.
São Paulo, São PauloAges 18 years+ - NCT06751537Recruiting
Testing a wearable device for COPD severity
This trial tests a wearable device (WearME) that tracks your breathing and activity to see how well it can measure COPD severity. It may help you and your doctor better understand your lung function at home.
Baltimore, MarylandAges 21–100 - NCT06756646Recruiting
Aerobic exercise and BFRT for COPD patients
This trial tests if adding a special band (BFRT) to walking or biking can help people with COPD breathe better and get stronger. It may be a good option if you have moderate to very severe COPD and haven't been in a rehab program lately.
Tainan, TaiwanAges 30–85 - NCT06772454Recruiting
Testing a new drug combo for advanced lung cancer with COPD
This trial tests whether adding an immunotherapy drug (atezolizumab) to standard chemotherapy and inhaled steroids helps people with advanced lung cancer who also have COPD. The goal is to see if this combination improves outcomes.
Guangzhou, GuangdongAges 18 years+ - NCT06776601Recruiting
Digital therapy for copd self-management
This trial tests a smartphone-based program to help people with COPD manage their condition at home. It may help you track symptoms and avoid flare-ups.
Beijing, Beijing MunicipalityAges 40 years+ - NCT06776731Recruiting
Does extra oxygen during rehab help lung disease patients?
This study tests whether breathing extra oxygen during outpatient pulmonary rehabilitation helps people with COPD. Participants will have their oxygen levels checked during exercise to see if extra oxygen improves their rehab results.
Winterthur, Canton of ZurichAges 18 years+ - NCT06780046Recruiting
COPD study for Brazilian patients
This study looks at the health of Brazilian adults with COPD. It aims to understand how the condition affects people and may help improve future treatments.
Aparecida de GoiâniaAges 18 years+ - NCT06782724RecruitingPhase 2
Psilocybin therapy for distress in advanced illness
This trial tests whether a single dose of psilocybin (a psychedelic medicine) can help reduce depression and distress in people with advanced lung disease, ALS, multiple sclerosis, or Parkinson's. You would receive preparation, the drug, and follow-up support in a safe, supervised setting.
PragueAges 18 years+ - NCT06850961Recruiting
Digital health app for COPD self-management
This study tests a digital health app to help you manage COPD symptoms on your own. It focuses on people who have trouble with mucus and want to use a smartphone for their care.
Bergen, NorwayAges 18–90 - NCT06858748Recruiting
Mucus in airways: asthma, COPD, and chronic cough study
This study is looking at how mucus builds up in the airways of people with asthma, COPD, or chronic cough. Researchers will also compare findings to healthy volunteers. The goal is to better understand these conditions and find new ways to help.
Vancouver, British ColumbiaAges 18 years+ - NCT06878261RecruitingPhase 3
Tezepelumab for moderate to very severe COPD
This study tests a new medication called tezepelumab (given as a shot) to see if it can reduce COPD flare-ups in people with moderate to very severe COPD who have had recent flare-ups despite using inhalers. It may be an option for those with higher levels of eosinophils (a type of white blood cell) in their blood.
Cullman, AlabamaAges 40–80 - NCT06883305RecruitingPhase 3
Testing tezepelumab for moderate to severe COPD
This trial tests tezepelumab, an injected medication, for people with moderate to very severe COPD who still have flare-ups despite using standard inhalers. It may help reduce flare-ups and improve breathing for those with higher eosinophil levels.
Foley, AlabamaAges 40–80 - NCT06915740Recruiting
Virtual Pulmonary Rehab for COPD Patients
This study tests a virtual (online) pulmonary rehabilitation program for people with COPD. If you join, you will participate in exercises and education from home, with remote support from the study team.
Turku, Southwest FinlandAges 18 years+ - NCT06952881Recruiting
Studying COPD types and treatable traits
This study looks at different forms of COPD to find better ways to treat them. It may help you understand your own condition and receive more personalized care.
Hong KongAges 40 years+ - NCT06956742Recruiting
Breathing device study for COPD shortness of breath after exercise
This trial tests a device that briefly opens your airways to help release trapped air after exercise. It may reduce shortness of breath and improve your daily life with COPD.
Rouen, NormandyAges 18 years+ - NCT06959095RecruitingPhase 3
Depemokimab for COPD with type 2 inflammation
This trial tests a new medicine, depemokimab, given as an injection to help reduce flare-ups (exacerbations) in adults with moderate to severe COPD who have a certain type of inflammation. The goal is to see if it can keep you healthier for longer with fewer serious breathing attacks.
Loxahatchee Groves, FloridaAges 40–80 - NCT06961214RecruitingPhase 3
Testing a new biologic for COPD with type 2 inflammation
This trial tests a medicine called depemokimab for people with COPD and a specific type of inflammation (type 2). It aims to see if it can reduce flare-ups when added to standard inhaler therapy.
Sheffield, AlabamaAges 40–80 - NCT06974981Recruiting
Using lung cancer screening to find and treat COPD
This study looks at how lung cancer screening can also help find and manage COPD, a lung condition that often goes undetected. If you are a current or former smoker and meet certain age and smoking history criteria, you may join to help improve screening and care for both lung cancer and COPD.
Philadelphia, PennsylvaniaAges 50–80 - NCT07000604Recruiting
How inhaler use affects oral health in COPD patients
This study looks at how using a metered dose inhaler (a common type of inhaler) might impact your mouth and teeth if you have COPD. It aims to help understand and improve oral care for people using these inhalers.
ÇankırıAges 35–80 - NCT07022704Recruiting
Doxapram to help COPD patients breathe easier off the ventilator
This trial tests if the drug doxapram can improve diaphragm movement in COPD patients who are being taken off a ventilator during a breathing trial. It aims to make the transition smoother and more successful.
Cairo, Cairo GovernorateAges 20–65
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Common questions
- Are there clinical trials for chronic obstructive pulmonary disease severe?
- Yes. Clin2 currently lists 197 recruiting chronic obstructive pulmonary disease severe studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic obstructive pulmonary disease severe trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic obstructive pulmonary disease severe trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.