Clinical trials
Chronic Obstructive Pulmonary Disease Severe clinical trials
Below are recruiting chronic obstructive pulmonary disease severe clinical trials, each written for real people, not researchers. We’re tracking 197 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06068322Recruiting
Very intense interval training for people with COPD
This study tests whether a very intense, short burst of exercise (supramaximal high-intensity interval training) is safe and effective for people aged 60 and older with or without COPD. It aims to see if this type of exercise can improve fitness and daily life.
Hasselt, DiepenbeekAges 60 years+ - NCT06068647Recruiting
Ultrasound and breathing tests for lung disease patients
This study uses ultrasound and sensors to monitor lung health in people with certain lung conditions, including those that cause scarring or breathing problems. It aims to find better ways to track lung disease, which could help manage your condition more effectively.
RomeAges 18 years+ - NCT06072690Recruiting
COPD and Heart Health Study
This study looks at how COPD affects your breathing and heart health. It is for people who are newly diagnosed with COPD and have a history of smoking.
Kaunas, Kaunas CountyAges 40 years+ - NCT06188065Recruiting
Eosinopenia and Recovery in Severe COPD Exacerbation
This study is looking at people admitted to the hospital for a severe COPD flare-up. It checks if a low level of eosinophils (a type of white blood cell) in the blood is linked to how quickly you recover from the flare-up.
North ShieldsAges 35 years+ - NCT06247397Recruiting
High-flow therapy for long-term oxygen users
This trial tests if adding high-flow oxygen therapy to your usual long-term oxygen therapy can help you breathe better. It is for people with COPD or ILD who use oxygen at home for at least 15 hours a day.
Karlskrona, Blekinge CountyAges 18 years+ - NCT06283966RecruitingPhase 3
Triple inhaler for COPD with heart risk
This study tests a triple-combination inhaler (budesonide, glycopyrronium, and formoterol) to see if it can help protect the heart and lungs in people with COPD who also have heart problems or high risk for them.
Athens, AlabamaAges 40–80 - NCT06376994RecruitingPhase 3
Clean air study for COPD
This study tests if using air cleaners at home improves lung health in people with COPD. If you qualify, you may get an air cleaner for your home and be followed for 12 months.
Birmingham, AlabamaAges 40 years+ - NCT06377410Recruiting
Ivy extract vs NAC for COPD: Which works better?
This study compares two treatments – a dry powder ivy extract and a common mucus-thinning medicine called NAC – to see which is safer and more effective for people with stable COPD. If you have COPD and are over 40, this trial could help find a better option to manage your symptoms.
Cheras, Kuala LumpurAges 40 years+ - NCT06390345Recruiting
Telehealth lifestyle and exercise for COPD and sleep apnea
This study tests a telehealth program that combines lifestyle coaching and exercise to help people with both COPD and sleep apnea improve their breathing and daily function. It may be a good fit if you are overweight, have a history of smoking, and feel short of breath during light activity.
Boise, IdahoAges 18 years+ - NCT06401512Recruiting
Digital follow-up for COPD patients in primary care
This trial tests a digital follow-up program for people with COPD who live at home. It aims to help manage your condition with remote support from your healthcare team.
Bergen, NorwayAges 35–80 - NCT06413524Recruiting
Vibration exercises for people with COPD
This trial tests if different types of vibration exercises can help people with COPD (a chronic lung disease). It may be a good fit if you have severe COPD or have had recent flare-ups, are not already exercising regularly, and are willing to try a new therapy.
Taipei, Wenshan DistAges 40–99 - NCT06447831Recruiting
Home exercise tests for lung disease
This study tests how well people with chronic lung disease can do exercise tests at home, either with a researcher watching remotely or by themselves. The goal is to see if home-based tests are as reliable as clinic-based ones.
QuébecAges 40 years+ - NCT06476769Recruiting
Blow bottle and postural drainage for COPD
This study tests whether combining a simple blow-bottle breathing exercise with postural drainage (lying in different positions to help clear mucus) can help people with moderate to severe COPD breathe better. It is designed for older adults who are stable and do not have other major health issues.
Multan Khurd, Punjab ProvinceAges 40–60 - NCT06480435Recruiting
Chest physiotherapy and lung squeezing for men with COPD
This study explores whether a chest physiotherapy technique (called lung squeezing) can help men with moderate-to-severe COPD breathe more easily. Participants will receive the therapy and be monitored for improvements.
Lahore, Punjab ProvinceAges 40–60 - NCT06480422Recruiting
Breathing exercises for moderate COPD
This study tests two breathing exercises—autogenic drainage and segmental breathing—to see if they help people with moderate COPD breathe easier. It may help you clear mucus and improve your lung function.
Lahore, Punjab ProvinceAges 40–60 - NCT06491043RecruitingPhase 2
Stem cells for COPD: safety and early effectiveness study
This trial tests whether an infusion of donor stem cells can help people with moderate to severe COPD breathe easier. If you are a current or former smoker aged 40 to 80, your symptoms are stable, and your lung function meets specific targets, you may be able to join.
New Taipei CityAges 40–80 - NCT06579872Recruiting
Heart-Lung Function and Foot Pressure in COPD
This study looks at how your heart and lungs work together (cardiopulmonary function) and how you put pressure on your feet while walking (plantar pressure) in people with COPD. It may help design better rehabilitation programs.
New Taipei CityAges 45–65 - NCT06595784Recruiting
COPD and heart disease study
This study looks at people who have both COPD (a long-term lung condition) and a heart problem. The goal is to learn more about how these two conditions affect each other and to help doctors provide better care.
AlexandroupoliAges 35–99 - NCT07566195RecruitingPhase 3
Long-term Safety of Tozorakimab in COPD Patients
This study follows patients who previously took part in a tozorakimab trial to see how safe the drug is over time. Tozorakimab is an antibody treatment designed to reduce flare-ups (exacerbations) in people with COPD, a chronic lung disease.
Aix-en-ProvenceAges 18–99 - NCT06615492Recruiting
Lung transplant study: comparing two ECMO methods
This study compares two ways of using a heart-lung machine (ECMO) during lung transplant surgery. The goal is to see if using ECMO only when needed works as well as using it for everyone. This could help reduce risks and improve recovery.
Edmonton, AlbertaAges 18 years+ - NCT06629675Recruiting
Personalized music to boost walking in COPD
This study tests whether a personalized music program can help people with COPD walk more and feel better. The music changes based on your walking speed to keep you motivated during a pulmonary rehab program.
Leicester, LeicestershireAges 18 years+ - NCT06655428Recruiting
A new treatment for severe emphysema using heat and liquid
This trial tests a procedure called Endobronchial Thermal Liquid Ablation (ETLA) that uses heated liquid to treat severe emphysema. It is for people with COPD who have very low lung function and shortness of breath, and who have not been able to get relief from other treatments.
Vienna, AustriaAges 40 years+ - NCT06677268Recruiting
Sleep and breathing rehab study for COPD patients
This study tests whether a respiratory rehabilitation program improves sleep quality in people with COPD. It may help you breathe better and sleep more restfully.
AmiensAges 50 years+ - NCT06682832Recruiting
Comparing lung health in COPD and PRISm patients
This study compares how people with COPD, those with a lung condition called PRISm (Preserved Ratio Impaired Spirometry), and healthy individuals feel and function. It aims to understand differences in symptoms and daily life.
AnkaraAges 40 years+
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Common questions
- Are there clinical trials for chronic obstructive pulmonary disease severe?
- Yes. Clin2 currently lists 197 recruiting chronic obstructive pulmonary disease severe studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic obstructive pulmonary disease severe trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic obstructive pulmonary disease severe trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.