Clinical trials
Chronic Obstructive Pulmonary Disease Severe clinical trials
Below are recruiting chronic obstructive pulmonary disease severe clinical trials, each written for real people, not researchers. We’re tracking 212 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07493629Recruiting
Study on immune status and disease control in inflammatory airway diseases
This study looks at how the immune system works and how well diseases like asthma, COPD, and others are controlled. You may join if you have one of these conditions or if you are a healthy volunteer or smoker without lung disease.
Ningbo, ZhejiangAges 18 years+ - NCT06772454Recruiting
Testing a new drug combo for advanced lung cancer with COPD
This trial tests whether adding an immunotherapy drug (atezolizumab) to standard chemotherapy and inhaled steroids helps people with advanced lung cancer who also have COPD. The goal is to see if this combination improves outcomes.
Guangzhou, GuangdongAges 18 years+ - NCT07482475Recruiting
COPD study for people getting lung cancer screening
This study looks at COPD in people who are already getting lung cancer screening. If you have COPD or a high risk for it, joining this observational trial may help researchers learn more about your condition.
Ann Arbor, MichiganAges 50–80 - NCT06776601Recruiting
Digital therapy for copd self-management
This trial tests a smartphone-based program to help people with COPD manage their condition at home. It may help you track symptoms and avoid flare-ups.
Beijing, Beijing MunicipalityAges 40 years+ - NCT06413524Recruiting
Vibration exercises for people with COPD
This trial tests if different types of vibration exercises can help people with COPD (a chronic lung disease). It may be a good fit if you have severe COPD or have had recent flare-ups, are not already exercising regularly, and are willing to try a new therapy.
Taipei, Wenshan DistAges 40–99 - NCT07472738Recruiting
Studying treatable traits in chronic airway diseases
This trial is studying people with chronic lung conditions, like COPD or asthma, to find treatable traits. It also includes healthy volunteers for comparison, to better understand what makes these diseases different and how to personalize treatment.
Beijing, Beijing MunicipalityAges 20–75 - NCT07474220Recruiting
Study of SLC25A48 in COPD
This study measures a protein called SLC25A48 in people with COPD (a lung condition that makes breathing hard) and in healthy people to learn if it plays a role in the disease.
New Taipei CityAges 18 years+ - NCT06401512Recruiting
Digital follow-up for COPD patients in primary care
This trial tests a digital follow-up program for people with COPD who live at home. It aims to help manage your condition with remote support from your healthcare team.
Bergen, NorwayAges 35–80 - NCT07464587RecruitingPhase 3
Inhaled study drug for moderate to severe copd
This trial tests an inhaled medication (given through a nebulizer) to see how well it improves breathing and quality of life in people with moderate-to-severe COPD. It may help reduce symptoms and flare-ups, but will require regular visits and lung function tests.
Chizhou, AnhuiAges 40–80 - NCT07469111Recruiting
Low-weight arm exercises with blood flow restriction for COPD patients
This trial tests whether doing light arm exercises while wearing a cuff that slightly restricts blood flow can help people with COPD improve their arm strength and function without heavy weights.
Malatya, BattalgaziAges 40–80 - NCT06655428Recruiting
A new treatment for severe emphysema using heat and liquid
This trial tests a procedure called Endobronchial Thermal Liquid Ablation (ETLA) that uses heated liquid to treat severe emphysema. It is for people with COPD who have very low lung function and shortness of breath, and who have not been able to get relief from other treatments.
Vienna, AustriaAges 40 years+ - NCT07441226RecruitingPhase 2
Stem cells for advanced COPD treatment
This trial tests whether adding umbilical cord stem cells to standard triple therapy can help people with Group E COPD. It aims to see if this approach improves lung function and quality of life.
Jakarta, Jakarta Special Capital RegionAges 40–75 - NCT07432191Recruiting
Testing a new ventilator for safe breathing support
This study tests a new breathing machine (INBENTUS VERSATILE ventilator) for people who need help breathing. It checks if the machine is safe and works well for patients who need a ventilator and then slowly come off it.
MurciaAges 18 years+ - NCT07418736RecruitingPhase 2
CM326 for moderate to severe COPD
This trial tests a new medicine called CM326 for people with moderate to severe COPD. It aims to see if the drug can reduce flare-ups and improve lung function.
Beijing, Beijing MunicipalityAges 40–85 - NCT07414108Recruiting
Predicting response to breathing support in COPD
This study looks at whether nighttime breathing problems can predict long-term success with a non-invasive breathing machine in people with COPD who have high carbon dioxide levels in their blood. The goal is to help doctors decide who will benefit most from this therapy.
BolognaAges 18 years+ - NCT07406048Recruiting
Effectiveness of a triple inhaler for COPD in Brazil
This study looks at how well a triple inhaler (BDP/FF/GB) works for people with severe COPD in Brazil. It may help those who have had at least one flare-up in the past year.
São Paulo, São PauloAges 40 years+ - NCT07402551RecruitingPhase 2
Testing RC1416 injection for COPD flare-ups
This trial tests an injection called RC1416 for people with moderate-to-severe COPD who still have flare-ups despite using triple inhaler therapy. It may help reduce those flare-ups and improve breathing.
Hefei, AnhuiAges 40–85 - NCT07394712Recruiting
A health program for COPD patients after rehab
This study tests a community-based maintenance program for people with moderate to severe COPD who have finished an initial 8-week pulmonary rehab. The goal is to help you stay active and keep your health gains.
Lleida, CataloniaAges 40–75 - NCT07382258Recruiting
Inhaled nitric oxide for COPD: a clinical study
This trial tests whether a gas called nitric oxide, breathed in through the nose or mouth, can help people with moderate to severe COPD. It could improve breathing and quality of life.
Nanjing, JiangsuAges 40–75 - NCT07382986Recruiting
COPD care in China
This study is a long-term patient registry collecting health information from people with COPD (chronic obstructive pulmonary disease) in China. Joining means you will receive regular check-ups and your doctor can track your condition over time, which may help improve management of your disease.
Hebi, HenanAges 40–85 - NCT07363694RecruitingPhase 2/Phase 3
Study of PF-07275315 for moderate to severe COPD
This trial tests a new medicine called PF-07275315 for people with moderate to severe COPD. It aims to see if it can help reduce flare-ups (sudden worsening of symptoms) when added to your usual treatment.
Birmingham, AlabamaAges 35–80 - NCT07355868RecruitingEarly Phase 1
Cell therapy for COPD
This trial is testing a new type of cell therapy called REGEND007 for people with COPD. It looks at whether the treatment can help improve how far you can walk and your overall breathing.
Yiwu, ZhejiangAges 40–80 - NCT06850961Recruiting
Digital health app for COPD self-management
This study tests a digital health app to help you manage COPD symptoms on your own. It focuses on people who have trouble with mucus and want to use a smartphone for their care.
Bergen, NorwayAges 18–90 - NCT07351734RecruitingPhase 2
Testing JKN2403 for COPD: a new treatment option
This study tests an experimental drug called JKN2403 for people with moderate to severe COPD. It aims to see if the drug can reduce flare-ups and improve breathing compared to a placebo (a dummy pill).
Guangzhou, GuangdongAges 40–80
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Common questions
- Are there clinical trials for chronic obstructive pulmonary disease severe?
- Yes. Clin2 currently lists 212 recruiting chronic obstructive pulmonary disease severe studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic obstructive pulmonary disease severe trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic obstructive pulmonary disease severe trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.