Clinical trials
Chronic Total Occlusion of Coronary Artery clinical trials
Below are recruiting chronic total occlusion of coronary artery clinical trials, each written for real people, not researchers. We’re tracking 65 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07422688Enrolling by invitation
Using light scans to find heart artery blockages
This trial uses a special light-based scan (optical coherence tomography, or OCT) to help doctors see inside your heart arteries and find the exact blockage causing your heart attack. It may help guide treatment more precisely.
GenkAges 18 years+ - NCT07397845Recruiting
Stents vs drug-coated balloons for small or complex heart vessels
This trial compares two treatments—stents and paclitaxel-coated balloons—for people with narrowed heart arteries that are small, long, or complex. It aims to find which option works better to restore blood flow.
Lucerne, Canton of LucerneAges 18 years+ - NCT05491668Recruiting
Testing heart artery narrowing before planned stent procedure
This study checks how severely blocked a coronary artery is using measurements taken during a planned heart catheterization, to help guide whether and how to do a stent (PCI). It may help doctors choose the best treatment plan for people with about 70% or more narrowing.
Boston, MassachusettsAges 18 years+ - NCT06915597Recruiting
Drug-coated balloons for coronary artery disease
This trial is studying how well drug-coated balloons work for people with coronary artery disease. It looks at their use in many different situations, including new blockages, re-narrowed stents, and complex cases. The goal is to see if they are a good option for opening blocked arteries.
DenizliAges 18 years+ - NCT05923489Recruiting
Follow-up angiography after stent placement in high-risk patients
This study checks how routine repeat heart blood-vessel imaging (angiography) after stent placement may help high-risk patients. It is meant for people who had a successful stent procedure and have certain higher-risk heart features.
Hangzhou, ZhejiangAges 18 years+ - NCT07386418Recruiting
Angina thresholds study for patients needing stent treatment
This trial is testing a new way to measure blood flow in the heart during exercise to better understand angina. You may be eligible if you have at least two blocked heart arteries and are scheduled for stent placement.
BasildonAges 18 years+ - NCT05055297Recruiting
Drug-coated balloon for severe leg artery blockage in lower legs
This trial studies a “drug-coated balloon” procedure to improve blood flow in people with severe, long-lasting poor circulation in the lower leg arteries. It may help reduce repeat blockage after treatment for selected artery lesions below the knee.
Chandler, ArizonaAges 18 years+ - NCT05824520Recruiting
CT blood-flow test guided treatment versus usual care
This trial compares a treatment plan guided by a special CT scan measurement of blood flow (called CT-derived FFR) versus standard medical therapy. It may help doctors choose the safest, most effective treatment based on how restricted blood flow looks on CT.
Hangzhou, ZhejiangAges 18 years+ - NCT06662500Recruiting
Shockwave balloon for hard heart blockages trial
This trial tests a new balloon catheter that uses sound waves to break up hard calcium blockages in heart arteries. It may be an option for people with stable chest pain or who have recovered from a recent heart attack, and who have a single, tough blockage.
La Jolla, CaliforniaAges 18 years+ - NCT05946629Recruiting
Drug-coated stent trial for narrowed heart arteries
This trial studies a drug-coated balloon (plus standard heart medicines) to treat a specific type of blockage in the heart arteries in people who need an intervention. It may help keep the artery open and prevent the narrowing from coming back, depending on how well you match the detailed heart and medication requirements.
Jonesboro, ArkansasAges 18 years+ - NCT04014803RecruitingPhase 4
Aspirin plus one blood thinner versus aspirin plus clopidogrel
This trial compares two common “blood thinner” combinations to prevent problems after a PCI procedure for complex blocked heart arteries. It may help your care team find which combination works better for people with higher-risk artery patterns.
SeoulAges 19–75 - NCT05701358Recruiting
Guiding heart stent decisions to fully treat blocked arteries after a heart attack
This trial compares two ways doctors decide which additional blocked heart arteries to treat with stents soon after a heart attack. It may help patients avoid later heart problems by testing a “complete revascularization” strategy planned after the initial culprit artery was treated.
Los Angeles, CaliforniaAges 18 years+ - NCT05936606Recruiting
Personalized blood thinner choice after stent placement
This trial tests whether tailoring anti-platelet (blood clot prevention) treatment can better protect people at higher risk of heart or blood-vessel problems after a drug-eluting stent. It may help prevent future clots and complications, especially in patients with certain high-risk health conditions or complex stent/scar tissue features.
SeoulAges 19–80 - NCT06075160Recruiting
RFR-guided heart artery treatment for moderate blockages
This trial uses a special pressure wire called RFR to help doctors decide whether a stent is needed for a moderate heart artery blockage. It aims to make sure only the blockages that really need treatment get stented, which may reduce unnecessary procedures.
Bucheon-si, Gyeonggi-doAges 20–90 - NCT06908499Recruiting
Long-term follow-up of a stent study for chronic total occlusions
This study looks at the long-term (10-year) outcomes of a specific stenting technique for patients with a chronic total occlusion (a complete blockage that has been there for at least 3 months) in a major heart artery. It aims to see how well the procedure works over time.
Pune, MaharashtraAges 19 years+ - NCT07373145Recruiting
CT scan check after drug-coated balloon treatment
This trial uses CT scans to see how well a special drug-coated balloon works for opening blocked heart arteries. It may be a good option if you have new blockages that are the right size for this treatment.
SeoulAges 19 years+ - NCT04451044Enrolling by invitation
Guided heart stent planning using an inside pressure sensor
This study tests whether using a tiny pressure sensor in heart arteries during a procedure can better guide where to place a stent. It may help doctors choose the safest and most effective stent plan by more accurately measuring artery narrowing.
Birmingham, AlabamaAges 18 years+
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Common questions
- Are there clinical trials for chronic total occlusion of coronary artery?
- Yes. Clin2 currently lists 65 recruiting chronic total occlusion of coronary artery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic total occlusion of coronary artery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic total occlusion of coronary artery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.