Clinical trials
Cirrhosis clinical trials
Below are recruiting cirrhosis clinical trials, each written for real people, not researchers. We’re tracking 261 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06483737Recruiting
Albumin for cirrhosis patients with hepatic encephalopathy
This trial tests whether giving human albumin through a vein can help people with liver cirrhosis who have confusion or drowsiness from a condition called hepatic encephalopathy. It is for patients with low albumin levels.
Shenyang, LiaoningAges 18 years+ - NCT06519162Recruiting
Liver-gut link study for liver disease patients and their families
This study looks at how gut bacteria differ in people with specific liver diseases and their household contacts. It may help researchers understand the connection between the liver and gut.
Daejeon, Jung-guAges 19 years+ - NCT06528314RecruitingPhase 3
Efruxifermin for NASH-related cirrhosis
This study tests a new medication called efruxifermin for people with cirrhosis (liver scarring) caused by NASH, a type of fatty liver disease. The goal is to see if the drug can help improve liver health and prevent further damage.
Birmingham, AlabamaAges 18–80 - NCT05490888RecruitingPhase 1
Dose study of PHIN-214 for mild to moderate cirrhosis
This Phase 1 study tests how the medicine PHIN-214 behaves in the body and what dose is tolerable in people with Child-Pugh A or B liver cirrhosis. It may help doctors plan safer dosing for future studies.
Chandler, ArizonaAges 18–75 - NCT06015022RecruitingPhase 2
Green tea extract to prevent liver cancer in cirrhosis
This trial tests whether a green tea extract called EGCG can prevent liver cancer in people with cirrhosis. It looks at how the extract affects liver cell changes that could lead to cancer.
Dallas, TexasAges 18 years+ - NCT06513195Recruiting
EUS-guided tool to check how well beta-blockers work for cirrhosis
This study tests a new way to measure if a type of blood pressure medicine called non-selective beta-blockers (NSBBs) is helping patients with cirrhosis. It uses a thin, flexible tube with a camera (endoscope) to measure pressures in the liver and a nearby vein. If you have cirrhosis with high pressure in the portal vein but haven't started NSBBs yet, this study may help your doctor decide if the medicine is working for you.
Leuven, Vlaams-BrabantAges 18–80 - NCT06458998Enrolling by invitation
Improving cancer screening for veterans
This study looks at ways to help veterans get screened for liver cancer (hepatocellular carcinoma) and colorectal cancer. The goal is to see if certain programs or tools can make it easier for veterans to complete these important cancer screenings.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06455280RecruitingPhase 1
A study of Siplizumab for autoimmune liver disease patients awaiting transplant
This trial tests a drug called Siplizumab in people with autoimmune hepatitis or primary sclerosing cholangitis who are on the liver transplant waitlist. It aims to see if the drug can help manage their condition before and after transplant.
New York, New YorkAges 18 years+ - NCT06432582Recruiting
Liver disease blood marker study for people with stiff livers
This study looks at whether certain micro-RNA levels in your blood can help predict how your chronic liver disease is progressing. It is for people who already have some liver stiffness (measured by a special ultrasound) and are being treated at the University Hospital St. Pölten.
Sankt Pölten, Lower AustriaAges 18 years+ - NCT06327308RecruitingPhase 1
MRI study for heart health in liver transplant candidates
This study uses a special heart MRI to check for a heart condition called cirrhotic cardiomyopathy in people waiting for a liver transplant. The results may help doctors better understand and treat heart problems in patients with cirrhosis.
BesançonAges 18–70 - NCT06306963Recruiting
Stomach blood vessel condition and digestion symptoms study
This study looks at people with a stomach condition called gastric antral vascular ectasia (GAVE) to understand how it affects digestion and causes symptoms. Researchers want to learn if stomach muscle function problems are common in this condition.
Rochester, MinnesotaAges 19 years+ - NCT06307964Recruiting
Gut bacteria in alcoholic hepatitis
This trial is looking at bacteria inside the liver of people with alcoholic hepatitis. It may help understand how these bacteria affect the disease and lead to better treatments.
LyonAges 18 years+ - NCT06169592Recruiting
Bleeding and Clotting Risks After Living Donor Liver Transplant
This study is for people with severe liver cirrhosis who are getting a liver transplant from a living donor. It looks at the risk of bleeding or clotting problems after the transplant, to help doctors better manage these risks.
TashkentAges 18–70 - NCT06121492Enrolling by invitationPhase 3
Amino Acid Drink for Muscle Loss in Liver Cirrhosis
This study tests whether taking a daily drink of branched-chain amino acids (a type of protein) can help people with liver cirrhosis who have lost muscle strength and mass. It may help improve muscle size and function.
Bangkok, BangkokAges 18–85 - NCT06121479Enrolling by invitationPhase 3
Testing oral amino acid supplements for advanced liver disease
This trial tests if taking branched-chain amino acids by mouth can help people with cirrhosis and ascites (fluid in the belly). It aims to improve nutrition and reduce complications.
Bangkok, BangkokAges 18–85 - NCT06084234RecruitingPhase 4
National liver cancer screening trial
This trial is testing a new way to screen for liver cancer in people with cirrhosis or chronic hepatitis B. It aims to find cancer earlier so it can be treated more effectively.
Los Angeles, CaliforniaAges 18–85 - NCT06061328Enrolling by invitation
Project OASIS: Finding better ways to improve care for cirrhosis
This trial tests different approaches to help doctors and hospitals improve care for veterans with cirrhosis. If you have cirrhosis and are not post-transplant or currently being treated for liver cancer, you might be able to join and help find the best strategies.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06051617RecruitingPhase 3
Seladelpar for liver scarring in primary biliary cholangitis
This trial tests a medicine called seladelpar for people with primary biliary cholangitis (PBC) and cirrhosis, a form of liver scarring. The goal is to see if it can help improve liver health and reduce symptoms.
Birmingham, AlabamaAges 18 years+ - NCT05967273Recruiting
Cirrhosis treatment support system for hospitalized adults
This trial studies a computer-based “CDS” system designed to support care decisions for people hospitalized with cirrhosis. It may help doctors deliver more consistent, safer treatment while you’re in the hospital.
San Francisco, CaliforniaAges 18 years+ - NCT05899231Recruiting
Online strengthening program while you wait for a liver transplant
This trial tests an online prehabilitation program (strength and fitness training delivered digitally) to help people who are likely to need a liver transplant become stronger before transplant. It may benefit people who feel “frail” or “pre-frail,” since improving strength before surgery can help recovery.
Calgary, AlbertaAges 18 years+ - NCT05782556Recruiting
Freiburg TIPS Registry for portal hypertension patients
This is a registry study that collects information from people who need a procedure called TIPS for portal hypertension. It may help doctors better understand outcomes and care for both cirrhotic and non-cirrhotic causes of portal hypertension.
Freiburg im BreisgauAges 18–100 - NCT05749822RecruitingPhase 2/Phase 3
Fenofibrate for primary biliary cholangitis with stable cirrhosis
This trial studies whether fenofibrate (a cholesterol medicine) can improve outcomes in people with primary biliary cholangitis (PBC) who already take ursodeoxycholic acid (UDCA) but still have abnormal liver blood tests. It specifically looks at people with “compensated” (stable) cirrhosis—meaning the liver disease is present but not causing severe complications right now.
Beijing, Beijing MunicipalityAges 18–75 - NCT05744713Enrolling by invitation
Study of adults with long-term liver disease using health records
This observational study looks at adults with chronic liver disease (including cirrhosis) to better understand how people are managed and how they feel over time. Because it does not change your treatment, it may help researchers improve care and patient support.
Los Angeles, CaliforniaAges 18 years+ - NCT05623150Recruiting
Biopsy-based study for alcohol and metabolic liver disease
This trial studies people with liver disease linked to alcohol use or metabolic syndrome (a cluster of conditions like weight gain and insulin resistance). It uses recent standard-of-care liver biopsy results to better understand these chronic liver problems and how they relate to cancer risk.
NiceAges 18 years+
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Common questions
- Are there clinical trials for cirrhosis?
- Yes. Clin2 currently lists 261 recruiting cirrhosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cirrhosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cirrhosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.