Clinical trials
Cirrhosis clinical trials
Below are recruiting cirrhosis clinical trials, each written for real people, not researchers. We’re tracking 261 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07058155RecruitingPhase 4
TIPS and weight-loss surgery for liver disease with high blood pressure
This trial tests if doing a TIPS procedure (to lower blood pressure in the liver) before weight-loss surgery (sleeve gastrectomy) helps people with advanced liver disease. It's for those who have cirrhosis and very high blood pressure in the liver, and who qualify for sleeve gastrectomy.
Cleveland, OhioAges 18–70 - NCT07053488RecruitingPhase 1/Phase 2
Gene-edited liver transplant to lower rejection risk
This trial tests a liver transplant using a donor organ that has been gene-edited to reduce the risk of rejection. It may help people who need a liver transplant and are not a perfect tissue match with their donor.
Beijing, ChangpingAges 16–85 - NCT07036874Recruiting
Predicting outcomes in liver cancer with non-invasive tests
This study uses non-invasive tests, like scans or blood tests, to predict how well people with liver cancer (hepatocellular carcinoma, or HCC) will do after curative treatment. It may help doctors better understand your condition without needing invasive procedures.
Hong KongAges 18 years+ - NCT07042919RecruitingPhase 1/Phase 2
Zanzalintinib for advanced liver cancer after prior treatment
This trial tests a new drug called zanzalintinib for people with advanced liver cancer (HCC) that can't be treated with surgery. You may join if your cancer has gotten worse after at least one prior treatment, or you couldn't tolerate that treatment.
Chicago, IllinoisAges 18 years+ - NCT07042308Recruiting
Study of advanced chronic liver disease over time
This study follows people with advanced chronic liver disease to understand how their condition changes over time. If you have cirrhosis or high liver stiffness, you may be able to join to help researchers track the disease and learn more about it.
Hong KongAges 18 years+ - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT06948565Recruiting
Cirrhosis patients in the ICU: a 10-year review
This study looks back at medical records of people with cirrhosis who were treated in an intensive care unit (ICU) over the last 10 years. Researchers want to understand what factors affect their recovery and outcomes.
BesançonAges Any age - NCT06920043RecruitingPhase 2
Study of a new drug for cirrhosis from fatty liver disease
This trial tests a new medication (efimosfermin alfa) for people with cirrhosis (liver scarring) caused by MASH, a type of fatty liver disease. It aims to see if the drug can help improve liver health.
Chandler, ArizonaAges 18–75 - NCT06911619Recruiting
Nutrition support for liver transplant patients
This study tests whether nutritional support can help reduce frailty in patients waiting for a liver transplant. It aims to improve strength and overall health before surgery.
LyonAges 18 years+ - NCT06890039RecruitingPhase 2
Study of a new treatment for severe alcoholic hepatitis
This trial tests an experimental drug for people with severe alcoholic hepatitis that did not improve with steroids. Participants should have a moderate level of organ failure, but not require a breathing tube or kidney dialysis.
London, Greater LondonAges 18–75 - NCT06871111RecruitingPhase 1
Bacteria treatment study for liver disease patients
This trial tests whether giving a mixture of helpful bacteria can improve gut health in people hospitalized with serious liver problems. It aims to see if restoring these bacteria can help with recovery.
Chicago, IllinoisAges 18 years+ - NCT06863012Recruiting
Measuring liver pressure with endoscopy: a new method
This trial compares a newer, less invasive method (using an endoscope) to measure pressure in the liver's blood vessels with the standard technique. It may help people with liver disease or suspected cirrhosis better understand their condition.
BarcelonaAges 18–85 - NCT06838468Enrolling by invitation
Study on liver health in alcohol detox patients
This study is looking at liver health in people staying in a detox unit for alcohol use disorder. Researchers want to see how common liver problems are in this group. Participating involves extra tests like blood work, an ultrasound, and a special liver scan (FibroScan).
Sabadell, BarcelonaAges 18–75 - NCT06840652Enrolling by invitation
Baclofen for alcohol withdrawal in liver disease
This trial tests if baclofen, a medicine for alcohol dependence, is safe and works for people with chronic liver disease who are actively drinking. It may help you stop drinking alcohol safely.
Sabadell, BarcelonaAges 18–75 - NCT06831565Recruiting
Comparing two blood-transfusion strategies for liver patients before procedures
This trial tests whether using a slightly different target on a blood-clotting test (ROTEM) can reduce the need for blood transfusions in people with liver disease who need a procedure. If you have cirrhosis or ACLF with severe clotting problems, this study may help your doctors decide how much blood product to give you before the procedure.
New Delhi, National Capital Territory of DelhiAges 18–75 - NCT06794853Recruiting
TIPS for improving muscle wasting in liver cirrhosis
This study looks at how a treatment called TIPS (a procedure to reduce pressure in the liver) might help improve muscle wasting (sarcopenia) in people with liver cirrhosis. If you are scheduled for TIPS, researchers want to see if it can stop or reverse muscle loss.
WuhanAges 18–80 - NCT06755632Recruiting
Hepatic fibrosis or cirrhosis screening trial
This trial screens for liver scarring (fibrosis) or severe scarring (cirrhosis) caused by hepatitis B or C. It aims to find people who may benefit from further care or treatment.
BobignyAges 18 years+ - NCT06741904Enrolling by invitation
Predicting liver disease worsening without invasive tests
This study looks at new, non-invasive methods to predict when chronic liver disease might get worse. It could help you and your doctor catch problems early without needing a biopsy or other invasive procedures.
Guangzhou, GuangzhouAges 18–80 - NCT06723275Recruiting
A study on liver transplant for different liver diseases
This trial is testing a new way to see how well patients do after a liver transplant. It includes people with severe cirrhosis, other end-stage liver diseases, or liver cancer.
Ghent, BelgiumAges 18–70 - NCT05433467Recruiting
CT-guided locating for tiny liver cancer before surgery
This study tests a CT-guided method to find and precisely locate very small liver cancer spots before surgery. It may help surgeons remove the tumor more accurately when standard scans cannot clearly see it.
Yangzhou, JiangsuAges 18 years+ - NCT06675604Recruiting
Liver transplant data collection study
This study collects data from adults listed for liver transplants due to severe liver disease or liver cancer. It aims to improve transplant care by learning from real-world patient information.
ViennaAges 18–70 - NCT06680583Recruiting
Predicting recovery in cirrhosis with GI bleeding
This study looks at simple body measurements (like blood pressure and heart rate) to help predict how well people with cirrhosis (liver damage) who are having bleeding in their stomach or intestines will recover. It may help doctors make better treatment decisions.
TainanAges Any age - NCT06549673Recruiting
Stopping beta blocker in controlled cirrhosis
This study is checking if it is safe for people with cirrhosis (liver scarring) to stop taking a certain blood pressure medicine (non-selective beta blockers) if their main liver problem is under control. If you've had varices or bleeding in the past and your liver is now stable, this trial will see if you can safely stop the medicine.
SydneyAges 18 years+ - NCT06619106Recruiting
Screening tool for minimal hepatic encephalopathy
This study tests a new cognitive tool to quickly and reliably detect minimal hepatic encephalopathy, a subtle brain change that can occur in people with liver disease. If you have a liver condition like fibrosis or cirrhosis and are already scheduled for a full evaluation (neuropsychological tests, MRI, EEG, and blood ammonia), this tool could help simplify future screening.
ParisAges 18–70
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Common questions
- Are there clinical trials for cirrhosis?
- Yes. Clin2 currently lists 261 recruiting cirrhosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cirrhosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cirrhosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.