Clinical trials
Decompensated Cirrhosis clinical trials
Below are recruiting decompensated cirrhosis clinical trials, each written for real people, not researchers. We’re tracking 31 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06533852RecruitingPhase 3
Fecal transplant trial for liver cirrhosis complications
This study tests whether stool from healthy donors can help people with advanced liver disease (cirrhosis) who have had complications like fluid buildup. You would receive the transplant through a colonoscopy or enema.
BarcelonaAges 18 years+ - NCT06764966RecruitingPhase 2
Statin and beta blocker study for liver disease
This trial tests if adding a statin to beta blocker treatment helps people with advanced liver disease (cirrhosis) who have had complications like fluid buildup, confusion, or bleeding. It is for patients who are already taking a non-selective beta blocker and will be followed for 12 months.
Charleston, West VirginiaAges 18 years+ - NCT06855056Recruiting
Studying new markers for recovery from liver cirrhosis complications
This study looks at new blood markers to better predict recovery in patients hospitalized for complications of cirrhosis (like fluid buildup, confusion, or bleeding). You may qualify if you were recently hospitalized for these issues and are expected to go home soon.
Clichy, FranceAges 18–80 - NCT03905746Recruiting
Study tests microRNA markers in worsened liver cirrhosis
This study looks at microRNA (tiny molecules in blood) to better understand what’s happening during sudden worsening of cirrhosis. It may help doctors recognize and monitor decompensated cirrhosis more accurately.
LyonAges 18 years+ - NCT07172035Recruiting
TIPS and liver recovery in decompensated cirrhosis
This trial studies whether a procedure called TIPS (a stent placed in the liver to improve blood flow) can help people with advanced liver disease regain better liver function. It is for patients who have had complications like severe bleeding from the stomach or difficult-to-control fluid buildup (ascites).
ChangshaAges 18–80 - NCT07002827Recruiting
Growth factors for early decompensated cirrhosis
This study tests whether a combination of two medicines (G-CSF and darbepoetin) given in one or more cycles can improve the body's immune and metabolic health in people with early-stage decompensated cirrhosis (advanced liver disease with mild complications). It compares these treatments with standard medical care.
New Delhi, National Capital Territory of DelhiAges 18–70 - NCT06212635Recruiting
Bleeding risk in liver cirrhosis and liver cancer
This trial studies bleeding problems in people with advanced liver cirrhosis or liver cancer. It aims to improve understanding of when blood transfusions or treatments are needed.
Stockholm, HuddingeAges 18 years+ - NCT06937307RecruitingPhase 2
Droxidopa for low blood pressure in cirrhosis with kidney injury
This trial tests a medication called droxidopa to see if it can raise blood pressure in people with cirrhosis who also have acute kidney injury. If you have low blood pressure and are in the hospital with these conditions, this study may help improve your kidney function.
New York, New YorkAges 18–70 - NCT05056220RecruitingPhase 3
Albumin treatment for advanced cirrhosis with fluid buildup
This trial tests whether a personalized long-term albumin (a blood protein medicine) can help people with advanced liver scarring who have fluid in the belly (ascites). It compares the personalized albumin approach to standard care to see if it improves outcomes over time.
LeuvenAges 18 years+ - NCT07299110Recruiting
Whey vs. egg protein for ammonia levels in liver cirrhosis
This trial compares how whey protein and egg white protein affect ammonia levels in people with cirrhosis caused by alcohol. The goal is to see which protein source is safer for your liver.
New DelhiAges 18–70 - NCT04801290Recruiting
TIPS procedure for people with worsening liver cirrhosis
This trial studies the TIPS procedure in people with decompensated (worsening) liver cirrhosis to see how it helps. You may be considered if you need a TIPS procedure and can receive care at the study hospital.
Hanover, Lower SaxonyAges 18–99 - NCT05895136RecruitingPhase 2
Albumin plus blood thinner for severe cirrhosis after hospital recovery
This Phase 2 trial tests whether giving albumin together with enoxaparin (a blood thinner) can improve outcomes for people hospitalized with decompensated cirrhosis who are at high risk. It may help your recovery after certain serious liver-related complications and reduce the chance of poor outcomes.
ClichyAges 18–80 - NCT06431919Recruiting
Adding statin to carvedilol for cirrhosis with heart problems
This trial tests whether adding a statin (simvastatin) to the usual heart medication carvedilol helps people with both cirrhosis and a related heart problem live longer and avoid serious liver complications.
ChandigarhAges 18–65 - NCT07413549RecruitingPhase 1/Phase 2
Stem cell injection for hepatitis B cirrhosis
This trial tests an injection of stem cells from donated umbilical cords to see if it can help people with advanced liver scarring from hepatitis B. You may be able to join if standard treatments haven’t helped enough and you aren’t able to get a liver transplant.
WuhanAges 18–75 - NCT05224960RecruitingPhase 2
Stem cell treatment for worsening liver cirrhosis
This trial tests umbilical-cord stem cells to see if they can improve outcomes in people with decompensated (worsening) cirrhosis. You may be considered if your liver disease is moderate to severe (MELD 15–30) and you do not have certain high-risk problems right now.
Lanzhou, GansuAges 18–75 - NCT07488546Enrolling by invitationPhase 1/Phase 2
HCL001 cell therapy for advanced liver cirrhosis
This trial tests a new cell injection called HCL001 for people with decompensated cirrhosis (advanced liver scarring causing complications). The goal is to see if it's safe and helps improve liver function. It may be an option if you've tried standard treatments and meet specific health criteria.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07437755Recruiting
Guiding blood transfusions during procedures for cirrhosis
This study compares a special blood test (thrombelastometry) to standard tests to decide when to give blood products before invasive procedures in people with advanced liver cirrhosis. The goal is to see which method leads to better use of blood products and fewer complications.
Iași, IaşiAges 18 years+ - NCT06223893Recruiting
Smartphone app to improve care after cirrhosis hospitalization
This study tests how well a smartphone app helps people with cirrhosis who have been hospitalized for sudden liver problems. It aims to improve care and access to treatment after you go home.
BirminghamAges 18 years+ - NCT06396897Recruiting
Hospital at Home for Cirrhosis Recovery
This study tests whether recovering from cirrhosis at home, with a nurse visiting daily, works as well as staying in the hospital. You'll be enrolled in the Hospital at Home program and need a caregiver to help for the first two days.
Indianapolis, IndianaAges 18 years+ - NCT06039696Recruiting
Testing a new way to find infections in liver disease patients
This trial uses a DNA test to better detect infections in people with advanced liver disease who are hospitalized. It may help doctors find the right treatment faster.
Guangzhou, GuangdongAges 18–80 - NCT05783661RecruitingPhase 4
Antibiotic plan guided by infection tracking in cirrhosis
This study compares standard antibiotic treatment versus antibiotic choices guided by local infection tracking (epidemiological surveillance) in people with cirrhosis who have an acute worsening and likely a bacterial infection. It may help doctors choose antibiotics more accurately and safely in this high-risk situation.
BarcelonaAges 18 years+ - NCT06121479Enrolling by invitationPhase 3
Testing oral amino acid supplements for advanced liver disease
This trial tests if taking branched-chain amino acids by mouth can help people with cirrhosis and ascites (fluid in the belly). It aims to improve nutrition and reduce complications.
Bangkok, BangkokAges 18–85 - NCT06538077RecruitingPhase 4
BCAA vs. Rifaximin to Prevent Recurrent Hepatic Encephalopathy
This trial compares two treatments—BCAA supplements and rifaximin—to see which is better at preventing another episode of confusion or coma in people with cirrhosis who have already had one. If you qualify, you would receive one of these treatments for several months.
ChandigarhAges 18–65 - NCT06814990Recruiting
Heart and liver study for TIPSS patients
This study uses MRI and echocardiography to check heart function in people with alcohol-related liver cirrhosis who need a TIPSS procedure. It aims to learn more about how the heart works in these patients.
Jena, ThuringiaAges 18–99
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Common questions
- Are there clinical trials for decompensated cirrhosis?
- Yes. Clin2 currently lists 31 recruiting decompensated cirrhosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a decompensated cirrhosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a decompensated cirrhosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.