Clinical trials
Cirrhosis clinical trials
Below are recruiting cirrhosis clinical trials, each written for real people, not researchers. We’re tracking 270 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07241195Recruiting
Fatty Liver Study in Older Adults
This study follows older adults with fatty liver disease to understand how their metabolism changes over time and how it affects their overall health. It helps researchers learn more about the condition and its impact on the body outside the liver.
Hangzhou, ZhejiangAges 65–100 - NCT07252102Recruiting
High-flow oxygen during sedation for critical patients having GI endoscopy
This trial tests whether high-flow nasal oxygen (HFNC) reduces low oxygen levels during sedated gastrointestinal procedures. It is for patients with higher health risks (ASA grade III–IV) who need an endoscopy or treatment.
Shenzhen, GuangdongAges 18–80 - NCT07275554Recruiting
Gene patterns and risk prediction in hepatitis B liver failure
This study looks at how gene changes (methylation) in people with hepatitis B-related liver failure may predict how well they will do. It aims to create a risk score to guide treatment.
Jinan, ShandongAges 18 years+ - NCT07343037Recruiting
Diagnosing overactive immune response in ICU patients
This study is looking at patients who were in the intensive care unit and showed signs of a condition called HLH, where the immune system becomes overactive. Researchers want to understand how these signs were diagnosed and managed in the ICU.
StrasbourgAges 18 years+ - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT02931513Recruiting
Blood marker test in newly diagnosed PBC patients
This study looks at how a specific blood marker (sCD163) changes in people newly diagnosed with primary biliary cholangitis (PBC). It’s mainly meant to see whether this marker could help predict treatment response, especially before starting UDCA.
Aarhus C, Central JutlandAges 18 years+ - NCT07414095Recruiting
Frailty assessment before liver transplant and outcomes
This study looks at how frail liver transplant candidates are before surgery and whether that affects their recovery afterward. Participants will complete simple physical and mental tasks to help doctors better understand their overall health before the transplant.
IzmirAges 18–65 - NCT07424963Recruiting
Comparing two ways to measure liver pressure
This study compares a newer, less invasive method using an endoscope (EUS-PPG) with a standard catheter method (HVPG) to measure liver pressure in people with advanced liver disease. The goal is to see if the newer method is equally accurate and safer.
Prague, BohemiaAges 18–75 - NCT07429864Recruiting
Bulevirtide for hepatitis D: bile acids and gut bacteria
This study looks at how Bulevirtide, a treatment for hepatitis D, affects bile acids and gut bacteria. It may help patients with chronic HDV and stable liver disease who are already on HBV therapy.
RomaAges 18 years+ - NCT07439939Recruiting
Blood Clotting Study in Cirrhosis Patients Getting a TIPS
This study looks at blood clotting in patients with cirrhosis who are getting a TIPS—a tube placed in the liver to help blood flow. The study aims to understand how the procedure affects bleeding and clotting, which could help make it safer for people with liver disease.
VillejuifAges 18 years+ - NCT07461532Recruiting
Apixaban for late portal vein clot after spleen surgery
This trial is testing whether a blood thinner called apixaban can treat a blood clot in the main vein to the liver (portal vein) that appeared more than a year after spleen surgery in people with cirrhosis. It compares apixaban to a low-dose aspirin to see if one works better with fewer side effects.
Yangzhou, JiangsuAges 18 years+ - NCT07461545Recruiting
Apixaban for late portal vein clot after spleen surgery
This trial tests if apixaban, a blood thinner, is more effective than aspirin at treating blood clots in the portal vein that form more than a year after laparoscopic spleen removal in people with cirrhosis and an enlarged spleen.
Yangzhou, JiangsuAges 18 years+ - NCT07462091Recruiting
Nerve-guided surgery for enlarged spleen and bleeding risk
This study tests a special surgery using a nerve-guided technique to remove the enlarged spleen and reduce bleeding risk in people with cirrhosis and portal hypertension. It may help if you have an enlarged spleen and have had bleeding related to liver disease.
Yangzhou, JiangsuAges 18 years+ - NCT07553663RecruitingPhase 1
Testing a new liver disease treatment for fatty liver
This study tests how your body processes a new medication called miricorilant, designed to help people with fatty liver disease (MASH). You'll have liver scans or recent biopsy results and metabolic conditions like diabetes or high blood pressure.
San Antonio, TexasAges 18–75 - NCT07561138Recruiting
Nutrition and Exercise Training Before Liver Transplant
This study tests whether eating better and doing gentle exercise before your liver transplant can help you stay healthier and recover better after surgery. You'll work with a nutrition expert and exercise specialist to prepare your body for transplant.
Athens, AtticaAges 18–70 - NCT07598669Recruiting
Austrian Primary Biliary Cholangitis Registry Study
This is a registry study that collects health information from people with primary biliary cholangitis (PBC), a rare liver disease where the immune system damages bile ducts. By joining, you help researchers better understand PBC and improve care for patients with this condition.
Klagenfurt, CarinthiaAges 18 years+ - NCT07610837RecruitingPhase 2
Testing AZD2389 for fatty liver disease with scarring
This study tests whether a new drug called AZD2389 is safe and well-tolerated in adults with steatotic liver disease (fatty liver) that has progressed to advanced scarring. The trial aims to see if this drug might help slow or improve liver damage in people with this condition.
Chandler, ArizonaAges 18 years+ - NCT07312136Enrolling by invitation
Liver health follow-up in type 2 diabetes
This study follows up on people who already joined the EPSONIP trial to check how their liver health (MASLD) has changed over time. It uses MRI to look at the liver and does not test any new medicine.
Linköping, Östergötland CountyAges 18 years+ - NCT07298577Enrolling by invitation
Using blood test and ultrasound to find early liver cancer in Asia
This study tests whether adding a simple blood test (GAAD score) to a routine liver ultrasound can find early-stage liver cancer sooner in people with chronic liver conditions. It aims to improve detection in Asian populations at risk.
Bangkok Noi, BangkokAges 18 years+ - NCT07248722Enrolling by invitation
Pantoprazole after preventive variceal treatment
This trial tests whether a heartburn medication (pantoprazole) helps patients with liver cirrhosis who have had a procedure to treat enlarged veins in the esophagus or stomach. It looks at how well the medicine works when given after this procedure to prevent complications.
Shenyang, LiaoningAges 18 years+ - NCT06867731Enrolling by invitation
Using sound waves to measure liver stiffness
This trial uses a special ultrasound during endoscopy to measure liver and spleen stiffness. It may replace liver biopsy for some patients with cirrhosis or unexplained high liver enzymes.
Spokane, WashingtonAges 18 years+ - NCT06840652Enrolling by invitation
Baclofen for alcohol withdrawal in liver disease
This trial tests if baclofen, a medicine for alcohol dependence, is safe and works for people with chronic liver disease who are actively drinking. It may help you stop drinking alcohol safely.
Sabadell, BarcelonaAges 18–75 - NCT06838468Enrolling by invitation
Study on liver health in alcohol detox patients
This study is looking at liver health in people staying in a detox unit for alcohol use disorder. Researchers want to see how common liver problems are in this group. Participating involves extra tests like blood work, an ultrasound, and a special liver scan (FibroScan).
Sabadell, BarcelonaAges 18–75 - NCT06773260Enrolling by invitation
Using liver stiffness to predict varices in advanced liver cancer
This trial uses a simple ultrasound test (measuring liver and spleen stiffness) to predict if a patient with cirrhosis and advanced liver cancer has enlarged veins in the esophagus. The goal is to avoid unnecessary invasive procedures like endoscopy.
Bari, ItalyAges 18–80
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Common questions
- Are there clinical trials for cirrhosis?
- Yes. Clin2 currently lists 270 recruiting cirrhosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cirrhosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cirrhosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.