Clinical Study clinical trials

Study of MT1988 for people at high risk for psychosis

This trial tests a new drug called MT1988 in people who show early warning signs of psychosis. Researchers want to see if it changes certain markers in the body related to mental health.

TCM tools for inflammatory bowel disease

This study compares people with Crohn’s disease or ulcerative colitis to healthy volunteers to see if traditional Chinese medicine tools can help identify unique features of these conditions, like changes in tongue coating. It aims to improve how we diagnose and understand inflammatory bowel disease.

Restarting blood thinners after a serious stomach bleed

This study follows people who had a serious, non-surgical stomach/intestine bleed while taking a blood thinner, and looks at when and how they restart a DOAC (a type of blood thinner). It may help your care team reduce the risk of another bleed while still preventing stroke or blood clots.

Mobile health support for breast cancer screening in Kenya

This study tests a mobile health program that helps women in Nairobi, Kenya get screened for breast cancer earlier. It aims to guide women through the screening process and connect them with the right care.

5-ALA by mouth to reduce regrowth of desmoid tumors

This Phase 2 trial tests whether taking a medicine called 5-ALA by mouth after treatment can lower how often desmoid tumors come back in the same area. If you have a desmoid tumor that can be removed and you meet safety criteria, this study may help determine whether 5-ALA is effective and safe for you.

CT Imaging and Clinical Features to Predict Outcomes in Patients With Gastric Cancer

MRI-guided biopsy or treatment using a perineal grid approach

This study looks at a new way to do an MRI-guided prostate biopsy or ablation using a small “grid” approach through the area between the scrotum and anus. It may help doctors target suspicious spots on MRI more precisely while keeping the procedure safe.

Hall Technique vs. Traditional Crowns for Decayed Baby Molars

This study compares two ways to treat decayed baby molars in children ages 5–8: the Hall Technique (a newer method) and traditional stainless-steel crowns. Researchers will measure which method works better, reduces anxiety, takes less time, and costs less.

Study of uncontrolled mild to moderate asthma in Russia

This study is for adults with mild to moderate asthma that is not well controlled. Researchers will look at medical records to understand what treatments people are using and what their health is like over time.

Vulvovaginal cancer treatment study

This study looks at how well treatments like radiation, chemotherapy, or surgery work for people with vulvar or vaginal cancer, and how they affect quality of life. It includes patients treated between 2019 and 2023.

Switching from ustekinumab to guselkumab for psoriasis

This study is testing a medicine called guselkumab (Tremfya) for people with psoriasis who are already taking another biologic medicine, ustekinumab, but need to switch. The goal is to see how well guselkumab works in real-world use.

Tests a gel that helps wrist tendon movement after fracture repair

This study looks at whether a bio-dissolving (self-absorbing) gel improves how well the wrist flexor tendons glide after surgery for a distal radius fracture. You may be randomly assigned to use the gel or not, and the researchers will measure wrist tendon and clinical outcomes to see if it helps.

Study of new respiratory infections starting within 10 days

This is an observational study that follows adults who are newly sick with a respiratory infection that started within the past 10 days. It may help researchers understand what causes these infections and how patients do in emergency or hospital-care settings.

Study of a new treatment for blocked leg arteries

This trial studies a device-based treatment approach for people with blocked (narrowed or fully blocked) arteries in the thigh or behind the knee that reduce blood flow to the leg. It may help improve blood flow and walking ability, but you must meet specific artery and imaging requirements.

Whole-body MRI for Preventive Health Screening

This study uses whole-body MRI to see if it can find health issues early in people without symptoms. The goal is to learn if this scan can help predict clinically important conditions in routine preventive care.

Lazy Eye Treatment Registry for Luminopia Users

This registry collects information from people with lazy eye who have used Luminopia treatment for at least 12 weeks. It helps researchers learn more about how the treatment works in real life.

Effectiveness of Ustekinumab for Crohn's Disease

This study looks at how well Ustekinumab (Stelara) works for Crohn's disease in people who started the medication in 2024. Researchers want to understand its real-world benefits and safety.

Aortic repair study using less radiation

This study tests a new way to guide a complex aortic surgery (fenestrated endovascular repair) using less or no radiation. It may help people with aneurysms who need repair involving the arteries that supply the liver, gut and kidneys.

Walking recovery after serious lung blood clot

This study follows people who had a serious blood clot in their lungs that also affected their heart's right side. It tests how their ability to walk and move changes over 6 months, helping doctors understand recovery better.

Home blood pressure monitoring for older adults

This trial tests if checking your blood pressure at home can help you and your doctor manage high blood pressure better, especially if you also have other health conditions. You will use a home monitor and share your readings with your care team.

HPV screening study for healthy adults 40 and older

This study checks healthy adults aged 40+ for HPV in the mouth using a simple gargle rinse. It aims to see if this can help find early signs of oropharyngeal cancer.

Study of new treatment for microscopic colitis in remission

This study tests whether a new medication (SAR444336) can help adults with microscopic colitis stay in remission longer. It may be an option if you are already taking budesonide and have had flares in the past 8 months.

Testing how other drugs affect a new leukemia tablet

This study looks at how two common medicines, itraconazole and rifampin, change the levels of a new drug called Rocbrutinib in healthy volunteers. The results will help doctors understand how to use Rocbrutinib safely in future patients.

Study of blood and imaging biomarkers in pulmonary artery hypertension

This study tracks natural changes in “biomarkers” (measurable signals in blood) and imaging findings in people with pulmonary arterial hypertension (PAH) or suspected PAH. It also includes healthy people for comparison, helping researchers understand what these signals mean over time.