Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 2,033 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06102486Recruiting
Speech in noise study for mild cognitive impairment
This study looks at how well people with mild cognitive impairment (MCI) understand speech in noisy settings. It aims to find better ways to diagnose and help people with thinking and memory concerns.
Lebanon, New HampshireAges 55–80 - NCT03546387Recruiting
Anesthesia and brain thinking changes in children with retinoblastoma
This study looks at whether having anesthesia more than once (for eye/surgery treatment) affects children’s thinking and learning. It may help doctors plan safer care and better follow-up for children with retinoblastoma.
New York, New YorkAges 6–17 - NCT04751435Recruiting
Genetic testing education for cancer patients of diverse backgrounds
This study tests new educational materials about genetic testing for cancer patients. It aims to find the best ways to explain genetic testing to people from different backgrounds, especially Black, Latino, and non-Latino non-Black communities.
Brooklyn, New YorkAges 18 years+ - NCT07717853Recruiting
CO-OP therapy for kids with autism
This study tests a therapy called CO-OP that helps children with autism learn to plan and carry out everyday tasks like getting dressed or doing homework. We want to see if it helps kids become more independent.
Istanbul, IstanbulAges 7–10 - NCT07125378RecruitingPhase 1/Phase 2
Exercise program for older adults with memory decline
This six-week exercise program helps older adults with mild memory or thinking problems and trouble walking stay independent and safe at home. You will work with a trainer and wear an activity tracker to track your progress.
Gainesville, FloridaAges 65–90 - NCT07713641Recruiting
Testing gut bacteria's effect on brain function and inflammation
This trial looks at whether short-chain fatty acids (substances made by gut bacteria) can reduce inflammation and improve thinking skills (executive function). You'll receive an injection that causes mild, temporary inflammation (like a bad cold) and complete cognitive tasks.
LeuvenAges 18–45 - NCT07711730Recruiting
Telehealth support for kids with limb-girdle muscular dystrophy
This study tests an online program to help children and teens with limb-girdle muscular dystrophy improve their thinking, social skills, and emotional well-being. You join from home using a computer with a camera and internet.
Bilbao, BiscayAges 7–17 - NCT02740634Recruiting
Brain imaging study for Alzheimer's disease
This study uses brain scans to understand Alzheimer's disease and related conditions that affect memory, language, or vision. It looks at how changes in the brain happen over time in people with these diagnoses.
Rochester, MinnesotaAges 21–80 - NCT07234357Recruiting
Scent therapy for mood and behavior in early dementia
This trial uses pleasant scents (aromatherapy) to see if they can improve mood and behavior for people with early memory loss. It is designed for individuals who have a caregiver who can help them participate.
SingaporeAges 50–99 - NCT05965336Recruiting
Walking test study for nerve damage in diabetes feet
This study looks at how well people with diabetes-related nerve damage (diabetic peripheral neuropathy) can walk, using a treadmill and walking distance tests. It may help improve understanding of walking limits and how to measure change over time.
Pensacola, FloridaAges 45 years+ - NCT06560749Recruiting
Exercise to help thinking in bipolar disorder
This study tests whether a regular exercise program can help improve thinking and memory problems that often come with bipolar disorder. You must have stable mood and no recent changes to your medications.
São Paulo, São PauloAges 18–60 - NCT07220512Recruiting
Exercise help for ovarian, fallopian, or endometrial cancer
This trial tests a special exercise program during chemotherapy before surgery. It may help patients with certain gynecologic cancers get stronger and better prepared for treatment.
Winston-Salem, North CarolinaAges 55 years+ - NCT06507189Recruiting
How exercise affects older adults: a study
This study looks at how different older adults respond to exercise. It will help researchers understand why some people benefit more than others. You will be asked to do supervised exercise sessions and tests over about 6 months.
Pensacola, FloridaAges 60 years+ - NCT05799846Recruiting
Online strategies to help with weight loss
This study tests a cognitive (thinking-focused) approach delivered through the internet to help you lose weight. You may be eligible if you have overweight or obesity and can regularly complete online activities and visits.
Providence, Rhode IslandAges 18–70 - NCT02953899Recruiting
Using rewards-based therapy for rural problem gambling
This study tests a structured “reward for desired behavior” approach to help people with gambling disorder. It may be a good fit if you live in a rural or remote area and have been gambling recently.
Lethbridge, AlbertaAges 18–70 - NCT02972008Recruiting
Looking for blood markers that predict complications after TAVI
This study enrolls older adults having a minimally invasive heart valve procedure (TAVI) to find “epigenetic” risk markers—signals in the body that may predict who is more likely to have complications during the procedure. If you qualify, your blood and/or samples may be studied to improve safety for future patients.
LilleAges 70 years+ - NCT03140865Recruiting
Alzheimer’s disease research core for brain and memory testing
This study group collects detailed information from people with normal memory, mild cognitive impairment, or mild Alzheimer’s disease to support Alzheimer’s research. You may need multiple visits, brain scans, and sometimes a spinal fluid sample, with strict health and medication requirements to keep results clear.
Winston-Salem, North CarolinaAges 55 years+ - NCT03174938Recruiting
BioFINDER 2 study for healthy aging and memory problems
This study uses brain scans and a spinal fluid test to better understand memory and thinking changes in different groups, from people with healthy thinking to early or established dementia. If you qualify, it may help researchers learn what’s driving these conditions and how they progress.
ÄngelholmAges 20–100 - NCT03182400Recruiting
Brain and sense testing in healthy kids and adults
This study measures how your brain processes sounds, touch, and thinking tasks in healthy people. It mainly helps researchers understand normal sensory and thinking function, which can guide future studies and tests.
ToursAges 1–60 - NCT03206190Recruiting
Study for early SPG4 symptoms in family members
This study looks at people in families with a known SPG4 gene change (a SPAST mutation) to understand early, subtle signs and the beginning of symptoms. It may help researchers find better ways to detect SPG4 earlier, before full walking problems start.
TübingenAges 18–70 - NCT03217110Recruiting
Brain stimulation study for thinking and control
This trial tests whether stimulating the cerebellum (a part of the brain involved in coordination and learning) can improve “cognitive control,” or the ability to focus and manage thoughts. You may be able to join if you have a diagnosis they are specifically enrolling for and you can safely complete the stimulation and study procedures.
Iowa City, IowaAges 18–90 - NCT03568669Recruiting
Testing thinking and learning in congenital central hypoventilation syndrome
This study looks at thinking and memory in people with congenital central hypoventilation syndrome (CCHS) to better understand how the condition affects the brain. It may help researchers measure changes over time and guide future care.
Los Angeles, CaliforniaAges 3–85 - NCT03574207Recruiting
Brain stimulation study for memory in certain adults
This study tests a targeted, non-surgical brain stimulation method to help people with memory, especially remembering facts over time. It compares healthy adults and adults with amnestic mild cognitive impairment (aMCI), using sessions plus brain scans and memory testing.
Omaha, NebraskaAges 19 years+ - NCT03614962Recruiting
Warmth and TENS to improve thinking in dementia
This study tests whether using a warmth treatment and a gentle electrical nerve-stimulation device (TENS) can improve thinking and memory in people with mild to moderate dementia. It may help by supporting brain and nerve function, alongside your usual care.
Hong KongAges 65 years+
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Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 2,033 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.