Clinical trials
Cognitive Aging clinical trials
Below are recruiting cognitive aging clinical trials, each written for real people, not researchers. We’re tracking 159 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03954899Recruiting
Melatonin test for brain health in older adults
This study tests whether taking 5 mg of melatonin can improve thinking and brain health over time in older adults with early, mild symptoms. You may help researchers learn which brain changes and measures improve with melatonin.
Iowa City, IowaAges 56–85 - NCT05149742Recruiting
Study of hearing loss and thinking skills in midlife adults
This study looks at how severe hearing loss affects thinking and memory in adults aged 45–64. Researchers will compare people with significant hearing loss to people with normal hearing who are similar in age, sex, and education.
ParisAges 45–64 - NCT06726616Recruiting
Physical and cognitive aging study for older adults
This study looks at how physical and cognitive abilities change as we age. It's for older adults who are generally healthy and want to help researchers understand aging better.
Jacksonville, FloridaAges 55–85 - NCT03657745Recruiting
40 Hz light and brain training for Alzheimer’s
This trial tests whether a combination of 40 Hz light stimulation and cognitive (thinking) therapy can improve symptoms in people with Alzheimer’s disease. It may help by stimulating the brain and training thinking skills, while carefully checking eye and seizure history.
Miami, FloridaAges 50 years+ - NCT05468905Recruiting
Study of aging and early thinking changes over time
This study follows adults 40+ to better understand and track changes in memory and thinking as people age. It groups people with normal thinking, subjective complaints, mild cognitive impairment, early Alzheimer’s, and vascular (blood vessel) related brain changes to find what predicts progression.
Hangzhou, ZhejiangAges 40–99 - NCT07208279Recruiting
Cognitive Vitality Study: Can Axolt help memory?
This clinical trial is testing whether a special dietary supplement called Axolt can help keep your memory and thinking sharp as you get older. It is for healthy adults 55 and older who live independently and have no major memory problems.
West Palm Beach, FloridaAges 55 years+ - NCT07466290Recruiting
L-serine with strength training for seniors
This trial tests whether taking a supplement called L-serine along with a strength training program can improve muscle strength and function in older adults. It might help you stay strong and independent.
Vienna, State of ViennaAges 65–85 - NCT06679296Recruiting
Aging and Memory Loss Study in China
This study looks at how aging affects memory and thinking. It uses brain scans, a spinal tap, and other tests to understand cognitive decline better.
Wenzhou, ZhejiangAges Any age - NCT07171450Recruiting
Thinking skills training for older adults after COVID-19
This study tests a computer-based program to help improve memory and thinking in older adults who have ongoing cognitive problems after COVID-19. You may qualify if you are 60 or older and have had lasting thinking concerns since your infection.
Farmington, ConnecticutAges 60 years+ - NCT04184375Recruiting
Memory training for older adults with bipolar disorder
This study tests whether structured memory and thinking exercises (cognitive stimulation) help older adults with bipolar disorder who have mild to moderate thinking and memory problems. You may be offered guided sessions designed to improve everyday thinking skills while checking safety and fit for the program.
La RochelleAges 65 years+ - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT07419633Recruiting
Study on supplements to improve strength and thinking in older adults
This trial tests if two supplements, HMB and 2-HOBA, taken alone or together, can help improve muscle strength and mental function in healthy adults over 65. The goal is to see if these supplements can improve overall quality of life.
Montreal, QuebecAges 65 years+ - NCT03451383Recruiting
Study brain changes in older breast cancer patients
This study follows older women with newly diagnosed breast cancer to see who might develop thinking or memory problems over time. It may help researchers understand early brain risk and how treatment and other factors relate to cognitive decline.
Washington D.C., District of ColumbiaAges 60–105 - NCT06524388Enrolling by invitation
Cognitive training study for older adults with diabetes
This study tests if a special computer-based brain training program can help improve thinking and memory in older adults with diabetes who are at risk for dementia. It might help keep your mind sharp as you age.
BeijingAges 60 years+ - NCT07416799Recruiting
Home strength training for diabetes and mild memory loss
This study tests whether a home strength-training program using a smartphone app is doable for older adults with type 2 diabetes who also have mild memory problems. You'll do simple exercises at home, and the program may help improve your thinking and glucose control.
Galveston, TexasAges 55–80 - NCT05457725Recruiting
Study how aging affects learning to trust and distrust
This study looks at how thinking and learning processes change with age, especially around deciding what to trust. You may be asked to complete computer tasks and brief memory/thinking tests to understand these changes.
Gainesville, FloridaAges 18–100 - NCT03702907Recruiting
Study of aging and a brain sample bank
This study follows adults as they age and may collect biological samples for future research. It could help researchers understand early and late changes related to aging and brain health.
Washington D.C., District of ColumbiaAges 45 years+ - NCT07598409Recruiting
Brain Training Program for Older Adults in Spain
This study tests whether a computer-based brain training program can help older adults maintain or improve their thinking and memory skills. Researchers will compare people with normal thinking abilities to those with mild memory problems to see if the training helps both groups.
Madrid, MadridAges 65 years+ - NCT04800588Recruiting
Computer tests to study early Alzheimer’s changes
This study uses computer and touch-screen tasks to measure thinking changes in people who may be in the early, symptom-free stage of Alzheimer’s disease. It aims to understand how these brain-related changes show up on testing, which could help future detection or tracking.
Berkeley, CaliforniaAges 18–89 - NCT06956300Recruiting
TMS to help with thinking and memory in aging
This study uses a noninvasive brain stimulation technique called TMS to see if it can slow cognitive decline in older adults who are healthy or have very early signs of Alzheimer's disease. It aims to improve memory and thinking.
Boston, MassachusettsAges 40–99 - NCT07338682RecruitingPhase 2
L-Arginine for memory in older adults
This trial tests if L-Arginine, a natural amino acid, can improve thinking and memory in adults over 60 with mild to moderate memory problems. You may join if you have no other brain diseases or certain health conditions.
CairoAges 60 years+ - NCT05048680Recruiting
Breathing low-oxygen training to support brain blood flow in seniors
This study tests whether brief “low-oxygen” conditioning can improve blood flow to the brain and overall cerebrovascular (brain blood vessel) health in older adults. It may help people who are generally less active, as long as they have no major medical or safety barriers for the training.
La Tronche, Auvergne-Rhône-AlpesAges 60–80 - NCT07485387Recruiting
Korean cognitive aging study using smartphone app
This study looks at how thinking and memory change as people get older. It uses a smartphone app to track these changes over time in healthy older adults living in South Korea.
Seoul, Select One...Ages 60 years+ - NCT07639203Recruiting
Brain training app for healthy aging
This trial tests a digital brain-training program designed to improve thinking skills like planning and memory in healthy older adults. It may help you stay sharp as you age.
Rovereto, TrentoAges 65–75
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Common questions
- Are there clinical trials for cognitive aging?
- Yes. Clin2 currently lists 159 recruiting cognitive aging studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive aging trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive aging trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.