Clinical trials
Cognitive Aging clinical trials
Below are recruiting cognitive aging clinical trials, each written for real people, not researchers. We’re tracking 162 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07639203Recruiting
Brain training app for healthy aging
This trial tests a digital brain-training program designed to improve thinking skills like planning and memory in healthy older adults. It may help you stay sharp as you age.
Rovereto, TrentoAges 65–75 - NCT04171323Recruiting
Active mind training to improve thinking and delay dementia
This study tests an “active mind” computer-based program to help improve thinking skills and possibly slow the process toward dementia. You may be randomly assigned to different program options to see which approach works best for your goals.
San Francisco, CaliforniaAges 55–89 - NCT07594665Enrolling by invitation
Home-based cognitive health blood tests for older adults
This study invites people aged 65+ who are already part of the SHUTi MIND research program to do simple blood tests at home to check for early signs of cognitive changes. The goal is to make it easier for people to access brain-health testing without going to a clinic.
Charlottesville, VirginiaAges 65 years+ - NCT03653156Recruiting
Aging and brain study for mild memory loss and dementia
This study checks how age affects memory and thinking, and compares people with mild memory problems, Alzheimer’s disease types, vascular dementia, and healthy controls. You may help researchers understand brain changes using thinking tests, MRI scans, and blood or spinal fluid tests.
Hefei, AnhuiAges 18 years+ - NCT06377254Recruiting
How activity or inactivity changes your body
This study looks at how changing your physical activity level (either becoming more or less active) affects your whole body over 6 months. It is for people aged 50–65 who are overweight and either quite sedentary or fairly active, and who are willing to change their routine.
Nottingham, NottsAges 50–65 - NCT03370224Enrolling by invitation
Story memory training for older adults
This study tests a memory-skills training approach (the Modified Story Memory Technique) to help older adults with aging-related memory changes. You may be asked to do memory exercises, and some people may also complete an optional brain MRI scan.
East Hanover, New JerseyAges 65 years+ - NCT06107842Recruiting
Exercise program for older veterans' memory and thinking
This study tests whether an exercise program called Gerofit can help improve memory and thinking in older Veterans. If you join, you will take part in supervised exercise sessions to see how it affects your brain health.
West Los Angeles, CaliforniaAges 65 years+ - NCT03860857RecruitingPhase 3
Study biomarkers in memory aging and brain health
This Phase 3 study looks for blood/brain “biomarkers” linked to aging, memory changes, and early brain degeneration. It may help researchers better identify who is at risk and how biology relates to thinking and memory, using brain scans and thinking tests.
Irvine, CaliforniaAges 60 years+ - NCT05194787Recruiting
Online tests to spot early Alzheimer’s changes
This study looks at whether online motor (movement) and thinking tasks can detect early changes related to Alzheimer’s disease. You may be able to take part if you’re over 50 and do not already have a diagnosis of dementia.
Hobart, TasmaniaAges 50 years+ - NCT05597124RecruitingPhase 2
Exercise program to improve brain health in older Black adults
This Phase 2 study tests whether a structured exercise program can improve brain health in adults age 60 and older who are less active and have early thinking/memory concerns. It may help maintain or improve thinking abilities over time, with medical supervision throughout the study.
Newark, New JerseyAges 60 years+ - NCT06512922Enrolling by invitation
Cognitive training for older adults with high blood pressure
This trial tests whether a special computer-based brain training program can help older adults with high blood pressure think more clearly. It is done in your local community and aims to find a way to keep your mind sharp as you age.
Beijing, ShijingshanAges 60 years+ - NCT05014893Recruiting
Brain testing and rehab study for thinking changes
This study looks at how brain activity relates to thinking problems and whether a cognitive (thinking) assessment and rehab approach can help adults with memory or thinking changes. You may be asked to take thinking tests and complete study activities during rehab.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04997577Recruiting
Study of speech listening with high mental effort
This study tests how well you can understand speech when the task is mentally demanding. It may help researchers understand hearing and brain processing in older adults.
College Park, MarylandAges 65–85 - NCT06539403Recruiting
Thinking about memory and confidence with age
This study asks people who have been referred to a memory clinic about how they feel about their memory and memory changes with age. It aims to understand how confident you are in your memory and how that might shift over time.
LondonAges 65–120 - NCT07110896Recruiting
Can a probiotic reduce stress and sharpen focus in older adults?
This study tests a probiotic supplement called Humiome® Post LB to see if it can help reduce feelings of stress and anxiety and improve memory in adults aged 50-75. You may join if you are generally healthy, have noticed some mild memory slips, and are willing to keep your current diet and routines.
ParisAges 50–75 - NCT06423118Recruiting
Sleep apnea and thinking skills in older adults
This study looks at how sleep apnea affects thinking and memory in older adults. If you join, you'll wear comfortable, non-invasive sensors overnight to monitor your sleep and breathing patterns.
Toronto, OntarioAges 55–85 - NCT06993207Recruiting
Home brain monitoring study for cognitive decline
This study uses a special EEG headband to monitor brain activity at home in older adults. It aims to understand cognitive decline, including Alzheimer's and mild memory problems, and compare results with healthy volunteers.
Zaragoza, ZaragozaAges 60 years+ - NCT07623785Recruiting
Beef and Brain Health in Older Adults
This study looks at whether eating lean beef and dairy products daily affects brain health markers in people 65 and older. Researchers will track blood, urine, and other samples to see if beef consumption influences how your brain functions at the molecular level.
Brookings, South DakotaAges 65 years+ - NCT07414680Recruiting
Healthy aging study for adults 40+ in Taiwan
This study looks at how to help people age healthily. It is for adults 40 and older who are connected to Chang Gung Memorial Hospital in Taiwan. You will provide health information and may have some tests to track your well-being over time.
TaipeiAges 40 years+ - NCT06572332Enrolling by invitation
Brain scan study for sleep in older Chinese adults
This study uses brain scans to understand sleep problems in older Chinese adults. If you are 60+ and have trouble sleeping, you may help researchers find better ways to improve sleep.
Hong KongAges 50–90 - NCT06686186Recruiting
Hainan Community Memory Study
This study follows older adults in Hainan who live in the community. The goal is to understand thinking and memory changes over time.
Haikou, HainanAges 60–120 - NCT07151365Recruiting
Plant-based diets and healthy aging study
This study looks at how a plant-based diet might help people age in a healthy way. It is for adults 40 and older who are part of the Tzu Chi Foundation and are joining a health checkup program.
Dalin, ChiayiAges 40 years+ - NCT06248723Recruiting
Preventing memory decline in older adults with lifestyle changes
This study tests a personalized program of lifestyle changes (diet, exercise, brain training, etc.) to see if it can prevent memory loss and keep older adults independent. You may qualify if you are 60+, have mild frailty, and have certain risk factors for dementia.
MonzaAges 60 years+ - NCT07332299Recruiting
Brain stimulation and training for seniors with TBI
This study tests if a wearable brain stimulation device (tDCS) combined with computer-based training can improve attention and concentration in older veterans with a history of mild brain injury. It involves several sessions from home using a headset and computer.
Minneapolis, MinnesotaAges 65 years+
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Common questions
- Are there clinical trials for cognitive aging?
- Yes. Clin2 currently lists 162 recruiting cognitive aging studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive aging trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive aging trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.