Clinical trials
Cognitive Aging clinical trials
Below are recruiting cognitive aging clinical trials, each written for real people, not researchers. We’re tracking 153 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05929703Recruiting
Caring for hospitalized older adults
This study tests a new approach to caring for older adults in the hospital to prevent confusion (delirium). It involves having a family member or care partner stay with the patient during the hospital stay.
Orange, CaliforniaAges 70 years+ - NCT07209683Recruiting
Near-infrared light therapy for brain function in adults
This study tests whether shining a special near-infrared light on the head can improve how well your brain works and how clearly you think. It is for healthy younger and older adults who want to help find new ways to support brain health.
Oklahoma City, OklahomaAges 21–85 - NCT02604563Recruiting
Aging, blood changes, and health in older adults
This study examines why some older adults develop changes in their blood cells that may affect their health. Researchers will look for links between these blood changes, aging, and common health problems in older people.
St Louis, MissouriAges 50 years+ - NCT06622889Enrolling by invitation
Can changing how you see aging help memory?
This study tests whether changing how older adults think about aging can help with memory concerns. If you are 60+ and feel your memory or thinking is declining (but tests are normal), you may be able to join.
Beijing, Beijing MunicipalityAges 60 years+ - NCT05881239Recruiting
Remote smell tests to track early Alzheimer’s health changes
This trial uses remote, at-home (or remote) smell-based testing to help researchers assess health in people with preclinical Alzheimer’s disease and in control participants. It may help by showing how well smell-related changes can signal disease status over time.
Boston, MassachusettsAges 18–100 - NCT07721467RecruitingPhase 2
Cognitive training with psilocybin for brain flexibility
This study tests whether combining a brain-training program with a psychedelic drug called psilocybin can boost the brain's ability to change and adapt. It may help improve thinking and memory.
Baltimore, MarylandAges 65–120 - NCT06754202Recruiting
Farming and nature activities for mild memory loss
This study tests if spending time in farmlands and natural settings can help older adults with mild memory problems maintain their thinking abilities and overall health. It uses a special approach based on the Montessori method to keep participants engaged and active.
AnconaAges 55 years+ - NCT07074639Recruiting
Brain and body training with video games for frail older adults
This trial tests a fun home-based video game program that combines thinking exercises with physical movements to help older adults who are frail. The goal is to see if this training can improve physical and mental function.
ZurichAges 50 years+ - NCT06385951Recruiting
Virtual reality navigation test for early Alzheimer's detection
This study uses a virtual reality navigation task to detect early signs of Alzheimer's disease. It compares people with mild cognitive problems, mild Alzheimer's, and healthy older adults to see if this test can spot the disease earlier.
Ghent, East-FlandersAges 50–80 - NCT07669168Recruiting
Health study comparing usual care vs. extra support
This study looks at whether adding extra health support helps people stay healthier over time. You would be followed for a while and asked to share how you are doing.
Boulder, ColoradoAges 18 years+ - NCT06843161Recruiting
Robot program to help older adults be more active
This study tests if a robot can help older adults become more physically active. If you join, you would interact with a robot that encourages and guides you to move more each day.
Ottawa, OntarioAges 60 years+ - NCT06914284Recruiting
Apathy and thinking changes in older adults with bipolar disorder
This study looks at whether apathy and certain brain markers can help predict memory and thinking problems in people over 70 with bipolar disorder. If you are 70-85, have bipolar disorder, and are currently stable (no recent mood episodes), you may be able to join.
Rennes, Ile Et VilaineAges 70–85 - NCT06492109Recruiting
Blood study on sleep loss
This study looks at blood samples to understand how sleep loss affects the body. It may help find new ways to diagnose or treat sleep problems.
Hangzhou, ZhejiangAges 18–80 - NCT06501495Recruiting
Brain waves and memory in aging and Alzheimer's
This study looks at how brain waves (EEG) change during normal aging and early Alzheimer's disease. It compares three groups: people with early-stage Alzheimer's, healthy older adults, and healthy young adults. The goal is to understand how memory and thinking problems relate to slow brain wave activity.
ParisAges 18–85 - NCT05294068Recruiting
Study barriers to physical activity in aging with disabilities
This study looks at what makes it hard or easier for people with cognitive, physical movement, or sensory (hearing/vision) impairments to be active as they age. It may help improve support and services for physical activity at a rehabilitation/parasport clinic.
GarchesAges 6 years+ - NCT06345625Recruiting
Balance and walking with head movement in older adults
This study looks at how older adults keep their balance and walk when their head is moving. You may be asked to stand or walk while your head gently moves, so researchers can understand how your body reacts.
AntwerpAges 65–100 - NCT07799402Recruiting
How gut and brain health change with age
This study looks at how the bacteria in your gut are linked to brain health as you age. It includes people with normal memory, mild memory problems, or Alzheimer's disease, and aims to find ways to keep brains healthy as we get older.
Tampa, FloridaAges 18 years+ - NCT07666685Recruiting
Beetroot Extract for Health in Adults 75+
This study looks at whether taking beetroot extract can help improve quality of life and daily function in adults 75 and older. You will be asked to take the extract and complete simple health questionnaires.
Pamplona, NavarreAges 75 years+ - NCT06882252Recruiting
Lean protein in preschoolers: effects on thinking and health
This study looks at whether adding lean protein (like pork) to your preschooler's meals can help with their thinking skills and overall health. It is a good fit if your child is between 2 and 5 and does not have certain health conditions or food restrictions.
Charlottesville, VirginiaAges 2–5 - NCT05231798RecruitingPhase 2
PET and brain scans in adults with Down syndrome
This study looks at how well a brain chemical system works in adults with Down syndrome as they age, including how it relates to Alzheimer’s-type brain changes and thinking skills. It uses brain scans and memory/thinking tests to see whether these measures can help track risk or changes over time.
Nashville, TennesseeAges 18–55 - NCT05886114Recruiting
Lifestyle program to help older adults at risk of memory decline
This trial tests a multi-part lifestyle program to help older adults who may be starting to decline in thinking and memory. It may help slow cognitive decline by combining lifestyle changes over 24 months.
Hangzhou, ZhejiangAges 60–80 - NCT06995638Recruiting
Multitasking training for older adults
This study tests whether a special online training program can help older adults improve their ability to multitask and stay focused. You'll do some computer exercises at home and come in for a few checkups, including a blood test.
Newark, New JerseyAges 60–75 - NCT04754906Recruiting
Study how thinking abilities affect planning movement
This study looks at how well people can plan and control movements, and whether thinking ability affects that process. It compares healthy younger adults, healthy older adults, and older adults with mild cognitive problems.
DijonAges 18 years+ - NCT07388043Recruiting
AP-Brain for memory in older adults with memory concerns
This trial tests a supplement called AP-Brain to see if it helps with memory and thinking in healthy middle-aged and older adults who notice memory problems. You would take different doses of the supplement or a placebo for several weeks and complete memory tests.
London, OntarioAges 40–79
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Common questions
- Are there clinical trials for cognitive aging?
- Yes. Clin2 currently lists 153 recruiting cognitive aging studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive aging trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive aging trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.