Clinical trials
Cognitive Aging clinical trials
Below are recruiting cognitive aging clinical trials, each written for real people, not researchers. We’re tracking 153 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06307574Recruiting
Smartphone study to help older adults manage blood pressure medication
This study tests a digital tool called bpMedManage to help adults aged 60 and older remember and manage their blood pressure medications. It's for people who have some memory or thinking challenges and use a smartphone.
Tucson, ArizonaAges 60 years+ - NCT05460468Recruiting
Brain stimulation study to improve memory in aging
This study tests a brain-stimulation approach to help improve memory as people age. You may be able to take part if you can consent and meet safety and medical criteria, especially related to brain/nerve health and seizure risk.
Durham, North CarolinaAges 18–75 - NCT05124132Enrolling by invitation
Study of resilience and brain health after an earlier parent study
This trial looks at how resilience (how well people cope with stress) and brain health change over time in older adults who already joined an earlier study. You may be eligible if you participated in that “parent study.”
St Louis, MissouriAges 65 years+ - NCT05694039Recruiting
Track thinking changes in older adults with hearing loss
This study follows older adults who have age-related hearing loss to see whether wearing hearing aids helps protect thinking and memory over time. You may be included if your hearing loss is the type that hearing aids can usually improve and if your thinking test scores suggest mild cognitive difficulties.
Guangzhou, GuangdongAges 60–85 - NCT07404085Recruiting
Boosting thinking skills with training and medication in mood or schizophrenia disorders
This study tests whether adding a medication that may improve brain flexibility makes memory and thinking training work better for people with bipolar disorder, recurring depression, or schizophrenia spectrum disorders. It could help improve daily thinking skills and quality of life.
Frederiksberg, Capital Region of DenmarkAges 35–75 - NCT07735078Recruiting
Smart balance and thinking exercise for older adults
This study tests a smart digital tool that combines balance and thinking exercises to help older adults stay steady and prevent falls. If you are 55+ and can walk a short distance, you may be able to join.
Taipei, TaipeiAges 55 years+ - NCT07042087Recruiting
Brain health lifestyle study: timed eating and mindfulness
This study tests whether a combination of time-restricted eating and mindfulness can help protect brain health in people with early memory concerns. It lasts 9 months and includes regular guidance and support.
BrnoAges 60–80 - NCT07852650RecruitingPhase 1/Phase 2
Fall prevention app study
This study tests a digital program to help older adults reduce their risk of falling. It is designed for people who are generally healthy and can walk on their own, and it may help you feel steadier and safer.
Atlanta, GeorgiaAges 50 years+ - NCT07729930Recruiting
Creatine supplement study for healthy middle-aged women
This study is testing a creatine supplement (a substance that may help with energy and muscle function) in healthy middle-aged women. You may join if you are between 35 and 65, a non-smoker, and have a certain activity level.
LoughboroughAges 35–65 - NCT07695246Recruiting
Sleep therapy with melatonin for older adults with insomnia
This study tests whether adding a melatonin supplement to a type of talk therapy for insomnia (called CBT-I) helps older adults sleep better. It aims to improve sleep quality and reduce insomnia symptoms.
Hong KongAges 60 years+ - NCT07389213Recruiting
Can brain stimulation and hearing aids slow memory loss in older adults with hearing loss?
This trial tests whether a non-invasive brain stimulation technique (rTMS) combined with hearing aids can help slow down thinking and memory decline in older adults who have age-related hearing loss.
Guangzhou, GuangdongAges 50–85 - NCT07378787Recruiting
Time-restricted eating and low glycemic diet for menopause
This study tests if combining time-restricted eating with a low glycemic index diet can improve memory, slow aging, and boost metabolism in women going through perimenopause or menopause. It aims to see if this eating pattern helps with brain health and body changes during this life stage.
ZagrebAges 45–75 - NCT06953167Recruiting
Dementia study for older adults with prior brain checks
This study follows older adults who have already had amyloid testing, to track changes in memory and thinking over time. It helps researchers understand how to prevent dementia.
LondonAges 65 years+ - NCT06489873Recruiting
Lutein, Zeaxanthin, and Fish Oil for Macular Health
This study tests whether taking daily supplements of lutein, zeaxanthin, and fish oil can improve the protective pigment in your eyes. It may help people with low macular pigment and good vision who are not already taking high doses of these nutrients.
College Station, TexasAges 18–45 - NCT05107947Recruiting
Dynamic room lighting to improve sleep and daily body rhythm
This study tests whether changing the light in a hospital room can improve sleep and help your body clock work better in older adults. It may be most helpful if sleep problems or irregular daily rhythms are affecting you in the hospital.
MalmöAges 65 years+ - NCT04938349Recruiting
Dual-task training for memory and balance in older adults
This trial tests a type of training that challenges you to do two tasks at once to help with thinking and movement. It is for people over 55 who may have mild memory problems but do not have major brain, heart, or lung conditions.
Chicago, IllinoisAges 55 years+ - NCT07045259Recruiting
Exergaming vs. exercise for memory and movement in seniors
This study compares fun video games that get you moving (exergaming) with standard muscle-strengthening exercises. It aims to see which one better helps older adults who have both slower walking speed and memory concerns.
BalıkesirAges 65 years+ - NCT07740967Recruiting
Collagen and omega supplements for middle-aged women
This study tests whether daily collagen and omega-3 supplements can improve health in healthy middle-aged women. You would take the supplements for a period and have your health measured.
LoughboroughAges 35–65 - NCT06662045Recruiting
Iron deficiency and child brain development study
This study looks at whether iron deficiency anemia affects how babies and toddlers (6 to 24 months old) develop their thinking, learning, and behavior. It compares children who have iron-deficiency anemia with those who do not, to help doctors understand the impact on early brain development.
Shenzhen, China/GuangdongAges 6 months–6 years - NCT06181513RecruitingEarly Phase 1
Probiotics for mild Alzheimer's disease
This study tests whether daily probiotics (beneficial bacteria) can help people with mild Alzheimer's disease. It's an early-phase trial to see if probiotics are safe and might improve thinking and memory.
NicosiaAges 65–85 - NCT07377682Recruiting
Trazodone for depression with mild memory problems
This study tests how well the antidepressant trazodone works in older adults with major depression and mild cognitive impairment (early memory or thinking problems). It looks at real-world results in people starting this treatment.
Lodz, PolandAges 55 years+ - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT07139132Recruiting
The AHA Oneida study for Native American patients
This study tests a health program for Native American people ages 7 to 85 who get care through the Oneida Comprehensive Health Division. It aims to improve heart health and well-being.
Madison, WisconsinAges 7–85 - NCT05481749Recruiting
Neuropsychology testing for adults 80+ in Garraf
This study checks how older adults think and remember using a set of neuropsychological tests. It mainly looks at people age 80 and up living in the Garraf area who can travel to a study center.
Sant Pere de Ribes, BarcelonaAges 80 years+
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Common questions
- Are there clinical trials for cognitive aging?
- Yes. Clin2 currently lists 153 recruiting cognitive aging studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive aging trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive aging trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.