Clinical trials
Cognitive Behavioral Therapy clinical trials
Below are recruiting cognitive behavioral therapy clinical trials, each written for real people, not researchers. We’re tracking 321 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06145516Recruiting
Sleep program to ease pain after joint replacement
This study tests whether a sleep program can help with pain after knee or hip replacement. If you have insomnia and arthritis pain, you may be able to join before your surgery.
Uppsala, UpplandAges 18–100 - NCT05136703Recruiting
Study depression treatment effects in people living with HIV
This study looks at how depression and its treatment may affect the brain and immune-related body systems in people with HIV. You may be eligible if you have depression and a well-controlled HIV viral load, and you can safely complete brain MRI scans.
Coral Gables, FloridaAges 18 years+ - NCT05509166Recruiting
Therapy for sexual-minority women dealing with anxiety or depression and drinking
This trial tests a type of supportive psychotherapy to help sexual-minority women improve mental well-being and reduce drinking. It may help if you’re experiencing depression or anxiety and have been drinking heavily, and you’re not already in certain kinds of treatment.
New York, New YorkAges 18 years+ - NCT07372066Recruiting
Brain exercise group for seniors with memory concerns
This trial tests a cognitive stimulation therapy group for older adults living in residential homes who have mild cognitive impairment or dementia. The goal is to see if group activities can help keep the mind active and improve quality of life.
Hong Kong, Hong KongAges 60 years+ - NCT03948893Recruiting
Behavior program to help you quit nicotine
This study tests a structured counseling/behavior treatment to help people who smoke become nicotine-free. If you’re interested in quitting, you may be asked to complete questionnaires and follow a quit plan as part of the research.
Columbia, MissouriAges 18 years+ - NCT04700878Recruiting
Compassion course study for healthcare workers under stress
This trial tests whether a digital “compassion” training course can reduce stress in people who work directly with patients. You may be offered the course (or not, depending on random assignment) to see if it improves how you feel at work.
Vaxjo, Kronoberg CountyAges 20 years+ - NCT07136415RecruitingPhase 4
Comparing digital therapy, trazodone, and daridorexant for menopause insomnia
This trial tests three different treatments for insomnia that started or got worse during the menopausal transition. One is a digital therapy app, and the others are two different medications. The goal is to see which works best for women aged 40–62 who are in the early stages of menopause.
Boston, MassachusettsAges 40–62 - NCT05780814Recruiting
Treating insomnia to improve weight loss after breast cancer
This study looks at whether improving insomnia (trouble falling asleep or staying asleep) can help survivors of breast cancer lose weight more successfully through a structured behavioral weight loss program. It may help if sleep problems are making it harder to change eating and activity habits.
Washington D.C., District of ColumbiaAges 18 years+ - NCT00018057RecruitingPhase 2
Brain study of pediatric anxiety disorders
This study looks at how the brain works in children and adults with anxiety disorders. It uses brain scans (fMRI) and other safe tests to understand anxiety better.
Bethesda, MarylandAges 8–65 - NCT05142384Recruiting
Online therapy program for mothers with depression symptoms
This study tests an internet-based cognitive behavioral therapy (an online skills-based talk therapy) to help mothers with depression symptoms. It’s offered through Head Start, where participating moms and their children connect with the program.
Springfield, OregonAges 2 years+ - NCT05334992Recruiting
Support for family caregivers of people with dementia
This study aims to improve mental health for people who care for someone with dementia or memory problems. If you’re an unpaid caregiver and you have anxiety or depression symptoms, this program may offer structured support to help you cope better.
Lubbock, TexasAges 18–120 - NCT05424406Recruiting
Studying sleep timing changes in people with night-shift disorder
This study looks at how changes in your body clock (circadian timing) relate to “shift work disorder” in people who work night shifts. It may help researchers understand what drives symptoms and how to better target treatment.
Novi, MichiganAges 18 years+ - NCT07577947Recruiting
Digital tracking to help treat pregnancy and postpartum depression
This study tests whether wearing an Apple Watch and using a smartphone app can help doctors better understand and treat depression during pregnancy and after birth. You'll receive depression treatment through the study while the app and watch track your daily patterns.
Los Angeles, CaliforniaAges 18 years+ - NCT06375083RecruitingPhase 2
Computer therapy for suicide prevention and depression in Veterans
This trial tests two different computer-based therapy programs for Veterans: one for preventing suicide and one for treating depression. Both programs are designed to be done at home on your computer or tablet.
Aurora, ColoradoAges 18–65 - NCT07396220Enrolling by invitation
Psychotherapy with esketamine nasal spray for suicidal thoughts
This study tests combining a specific type of therapy (BCBT-SP) with esketamine nasal spray to help people with treatment-resistant depression who are having ongoing suicidal thoughts. The goal is to see if this combination can reduce suicidal ideation more effectively than either treatment alone.
San Diego, CaliforniaAges 18–70 - NCT07402681Recruiting
Tracking change in teens after trauma with weekly therapy
This study tests a type of talk therapy (TF-CBT) for teens who have been through trauma and still have upsetting symptoms like nightmares, flashbacks, or strong anxiety. It focuses on tracking how symptoms change over time and offers weekly sessions with a supportive adult.
Zurich, Canton of ZurichAges 12–18 - NCT05931289RecruitingPhase 2
Therapy plus brain scans after a recent suicide crisis
This Phase 2 study tests suicide-safety treatments given after a recent suicidal crisis or suicide attempt. It may help by reducing risk and understanding brain changes with follow-up brain scan visits.
Boston, MassachusettsAges 18 years+ - NCT05968560Recruiting
Online therapy to help youth at risk for psychosis
This trial tests a telehealth (video/phone) version of cognitive behavioral therapy to help young people who are at risk for developing psychosis. It may help by teaching skills to reduce symptoms and improve coping, with support from a key family or close person.
New York, New YorkAges 14–25 - NCT07218965Recruiting
Farm family connection study for lonely adults
This study tests if a program that helps build strong relationships can reduce loneliness in adults living in farming areas. You might be eligible if you feel lonely and live in an agricultural community.
Columbus, OhioAges 18 years+ - NCT07218471Recruiting
Cannabis reduction study for heavy users
This study tests if helping people reduce heavy cannabis use improves daily life. It's for adults with cannabis use disorder who want to cut back.
Charleston, South CarolinaAges 18 years+ - NCT07167641Recruiting
Support for parents and caregivers of young people with psychosis
This study focuses on supporting parents and caregivers of young people who have had a first episode of psychosis. The goal is to understand how to help you while you care for your loved one. If you’re a caregiver connected to a UNC Coordinated Specialty Care program, you may be able to join.
Chapel Hill, North CarolinaAges 18–99 - NCT06721559Recruiting
Home program for older adults with depression and mobility issues
This study tests a home-based program called Empower@Home for older adults who have depression and trouble moving around. It aims to see if the program helps improve mood and daily life—without adding extra outside therapy.
Ann Arbor, MichiganAges 50 years+ - NCT06584422Recruiting
Online program for depression in older adults
This study tests an online program called Empower@Home that helps older adults with symptoms of depression. It compares the program to usual care to see if it improves mood and well-being.
Ann Arbor, MichiganAges 50 years+ - NCT06094218Recruiting
Developing a suicide prevention tool for active duty members
This study is for active duty service members who are getting mental health care and have had recent suicidal thoughts. The goal is to develop a tool that helps predict how well treatments may work for preventing suicide, so you and your provider can make better decisions.
Columbus, OhioAges 18 years+
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Common questions
- Are there clinical trials for cognitive behavioral therapy?
- Yes. Clin2 currently lists 321 recruiting cognitive behavioral therapy studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive behavioral therapy trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive behavioral therapy trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.