Clinical trials
Postoperative Cognitive Dysfunction clinical trials
Below are recruiting postoperative cognitive dysfunction clinical trials, each written for real people, not researchers. We’re tracking 37 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07719712Recruiting
Thinking and confusion after prostate surgery in older adults
This study looks at how older adults' thinking and memory may change after a common prostate surgery, and whether some patients become confused or delirious afterward. It may help doctors understand who is at risk for these problems.
MuğlaAges 65 years+ - NCT03360838Recruiting
Prediction test for confusion after heart surgery in older adults
This study uses a short, self-answered thinking test before elective heart surgery to help predict who may develop confusion afterward. The goal is to improve early identification and care planning for patients at higher risk.
BaselAges 60 years+ - NCT04493996Recruiting
Cognitive training before heart surgery to protect memory
This trial tests whether brain-focused cognitive training before elective heart surgery can help reduce memory and thinking problems afterward. If you qualify, you may do language-based thinking exercises and complete short brain tests around the time of surgery.
Bad NauheimAges 18 years+ - NCT04523909Recruiting
Testing spinal fluid inflammation changes after aortic surgery
This study tracks inflammation-related lab markers in spinal fluid taken through a temporary drain during and after thoracic aortic surgery. It may help doctors understand what inflammatory changes happen around surgery and how they relate to recovery.
NijmegenAges 18 years+ - NCT05036538Recruiting
Reducing pre-surgery stress to help prevent confusion after heart surgery
This study tests whether a stress-reducing relaxation method before heart surgery can lower the risk of postoperative delirium (sudden confusion) and longer-term thinking problems. It may help you keep clearer thinking in the days and weeks after surgery.
Bad Nauheim, HesseAges 18 years+ - NCT05555693Recruiting
Brain chemistry study after surgery in older adults
This study looks at how brain “metabolomics” (small chemical signals in the brain/body) relate to thinking or mood problems that can happen after surgery in people age 65 and older. It may help doctors understand who is more likely to have these side effects after an operation.
Shanghai, Shanghai MunicipalityAges 65 years+ - NCT05990790RecruitingPhase 4
Comparing anesthetics and their effect on confusion after surgery
This study compares three different anesthesia medicines to see which one might lower the chance of confusion or delirium after major surgery. If you are 65 or older and having a long, planned non-heart surgery, this trial could help determine the safest option for you.
InnsbruckAges 65 years+ - NCT06005363Recruiting
Brain fluid study in shunt surgery patients
This study looks at brain fluid and drainage function in patients receiving a VP shunt for hydrocephalus. It may help understand how the brain clears waste products.
TaoyuanAges 60 years+ - NCT06133842Recruiting
Brain blood flow and confusion after surgery study
This trial looks at how well the brain controls its own blood flow during non-cardiac surgeries. It aims to see if problems with this regulation are linked to confusion after surgery (delirium).
Boston, MassachusettsAges 60 years+ - NCT06469515Recruiting
Thinking recovery after heart surgery in older adults
This study looks at how older adults recover their thinking and memory skills after heart surgery. You may be asked to do simple computer or paper tests to see how your brain heals.
GothenburgAges 65 years+ - NCT06658769Recruiting
Brain stimulation to prevent confusion after surgery in older adults
This study tests if transcranial magnetic stimulation (a gentle brain stimulation) can help prevent or reduce confusion or memory problems after major surgery in people over 60. If you already have mild memory issues, this might help protect your thinking skills.
São Paulo, São PauloAges 60–120 - NCT06704451Recruiting
IL-33 and memory after major abdominal surgery
This study looks at whether a protein called IL-33 is linked to memory and thinking problems that can happen after major abdominal surgery. It may help doctors find patients at risk earlier.
Kunming, YunnanAges Any age - NCT06761573Recruiting
Study on brain activity and confusion after head and neck surgery
This trial measures brain signals to see if they can predict confusion (delirium) after surgery. It may help identify patients at higher risk so they can get extra care.
BolognaAges 18–90 - NCT06817239Recruiting
Low-dose esketamine for preventing confusion after surgery in older adults
This study tests whether a low dose of the medicine esketamine can help prevent confusion after surgery in older adults at higher risk. You may qualify if you are 65 or older, planning a major non-cardiac surgery, and have certain health conditions like high blood pressure or diabetes.
Fuzhou, FujianAges 65–90 - NCT07000461Recruiting
Doppler test to predict memory problems after heart surgery
This study uses a noninvasive ultrasound test (transcranial Doppler) before heart surgery to see if it can help predict thinking or memory problems that may occur after the operation.
IstanbulAges 18–70 - NCT07113483RecruitingPhase 3
Remimazolam vs. Midazolam for sedation in older adults having orthopedic surgery
This trial compares two sedatives, remimazolam and midazolam, to see which one leads to better recovery of thinking skills after orthopedic surgery. It is for people aged 65 and older who are having surgery on a bone or joint while awake but relaxed.
BucharestAges 65 years+ - NCT05595954Recruiting
Personalized anesthesia plan to protect the brain during heart surgery
This trial studies whether tailoring anesthesia and monitoring the brain’s blood-flow control during heart surgery can improve neurological outcomes (brain-related function and recovery). It may help by guiding anesthesia in a more individualized way and checking how well the brain is protected during the operation.
BaselAges 65 years+ - NCT07452367Recruiting
Bentall surgery study: optic nerve and thinking ability
This study checks if swelling of the optic nerve sheath during heart surgery with a bypass machine is linked to changes in thinking ability after the operation. It may help understand why some people have mental fogginess after surgery.
Bursa, YıldırımAges 18–80 - NCT07483047Recruiting
Predicting memory changes after heart surgery in older adults
This study looks at older adults having heart surgery to find out who might have trouble thinking or remembering afterward. Researchers hope to build a tool to predict this risk so doctors can help sooner.
ShanghaiAges 65 years+ - NCT07598552Recruiting
Brain Function Changes After Same-Day Hip or Knee Surgery
This study checks whether patients who have hip or knee replacement surgery and go home the same day experience any temporary changes in thinking or memory. Researchers want to understand how anesthesia and surgery affect the brain in the short term.
SvendborgAges 70 years+ - NCT07637357Recruiting
How anesthesia affects thinking after weight-loss surgery
This study looks at how different types of anesthesia used during sleeve gastrectomy (a weight-loss surgery) may affect your memory and thinking skills after the operation. Researchers want to understand which anesthesia approach is safest for your brain.
Istanbul, SancaktepeAges 18–65 - NCT06423547Recruiting
Predicting confusion after surgery in older adults
This study looks at older patients (65 and older) who have had surgery and anesthesia. It aims to find who is at risk for confusion (delirium) and memory problems afterward. The goal is to help doctors prevent these issues.
BeijingAges 65–100 - NCT06176144Recruiting
Comparing two anesthetics for confusion after surgery in older adults
This trial compares two types of anesthesia (desflurane and sevoflurane) to see if one causes less confusion after surgery in older adults. It may help if you are 65 or older and having a non-heart, non-brain surgery lasting at least 2 hours.
Chengdu, SichuanAges 65–90 - NCT07396532Recruiting
iPad messages to prevent delirium after hip fracture surgery
This trial tests if audio-recorded messages played on an iPad can help prevent confusion (delirium) after hip fracture surgery in older adults. It is for people aged 60 and older who do not have a history of memory or thinking problems.
SingaporeAges 60 years+
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Common questions
- Are there clinical trials for postoperative cognitive dysfunction?
- Yes. Clin2 currently lists 37 recruiting postoperative cognitive dysfunction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a postoperative cognitive dysfunction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a postoperative cognitive dysfunction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Cognitive Dysfunction (POCD)
- Cognitive Dysfunction, Cognitive Disorder
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Cognitive Dysfunction
- Cancer-related Cognitive Dysfunction
- Post Operative Cognitive Dysfunction
- Postoperative Cognitive Decline
- Postoperative Gastrointestinal Dysfunction
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.