Clinical trials
Cognitive Health clinical trials
Below are recruiting cognitive health clinical trials, each written for real people, not researchers. We’re tracking 283 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04816006Recruiting
Breast cancer, thinking, and exercise study
This trial tests whether exercise can help thinking and reasoning in women over 50 who have had early-stage breast cancer. It compares a moderate exercise program with health education sessions.
Phoenix, ArizonaAges 50 years+ - NCT06479174Recruiting
Cognitive strategies after stroke with family support
This study tests if combining cognitive exercises with a safe, mild brain stimulation can help improve memory and thinking after a stroke. It also looks at how shared family health history might affect recovery.
Albuquerque, New MexicoAges 18 years+ - NCT05131035Recruiting
Trial for thinking-speed training to lower psychosis risk
This study targets problems with “processing speed,” or how fast your brain handles information, to see if it can improve social functioning and lower the risk of developing full psychosis. It’s for people who are considered at high risk for psychosis but do not already have schizophrenia.
Glen Oaks, New YorkAges 14–20 - NCT06036095RecruitingPhase 4
Comparing two types of anesthesia in older adults having surgery
This study compares two types of general anesthesia for older adults (70+) having planned non-heart, non-brain surgery that lasts at least 2 hours. The goal is to see which type might be better for preserving thinking and memory after surgery.
Portland, OregonAges 70–110 - NCT06597981Recruiting
Sport stacking program for mild dementia and caregivers
This trial tests a fun sport stacking activity for people with mild dementia and their family caregivers. It aims to improve well-being and connection through a simple, home-based program.
ChongqingAges 18 years+ - NCT07420478Recruiting
TF-CBT for autistic youth with trauma
This trial tests trauma-focused therapy for autistic youth who have experienced trauma. It aims to see if this therapy helps reduce trauma-related distress.
Lebanon, New HampshireAges 6 years+ - NCT07489105Recruiting
Yoga for better thinking with heart failure
This trial tests if a yoga program can help improve memory and thinking in people with heart failure. It's designed for adults 55 and older who are not already doing yoga and are able to take part in gentle physical activity.
Auburn, AlabamaAges 55 years+ - NCT03089827Enrolling by invitation
Tests how a brain imaging tracer spreads in Alzheimer’s risk
This trial uses a radioactive imaging tracer to see how it moves and settles in the brain in people with risk factors for Alzheimer’s disease. It may help researchers understand which people show tracer patterns linked to Alzheimer’s changes.
Winston-Salem, North CarolinaAges 55 years+ - NCT06107842Recruiting
Exercise program for older veterans' memory and thinking
This study tests whether an exercise program called Gerofit can help improve memory and thinking in older Veterans. If you join, you will take part in supervised exercise sessions to see how it affects your brain health.
West Los Angeles, CaliforniaAges 65 years+ - NCT05676255RecruitingPhase 2
SUPORT study for breast cancer survivors and their partners
This Phase 2 study looks at an online program for breast cancer survivors and their supportive partners who live together. The goal is to see whether the program helps survivors and partners during survivorship and adjustment after treatment.
Tucson, ArizonaAges 18 years+ - NCT07002996Recruiting
Virtual reality memory training for mild cognitive impairment
This study tests whether a special memory training program using virtual reality can improve thinking skills in people with mild cognitive impairment. It may help slow memory loss and keep your mind sharper.
Verdun, QuebecAges 55 years+ - NCT07142499Recruiting
Memory support program for older Chinese Americans with mild memory loss
This trial tests a memory support system designed for older Chinese Americans who speak Cantonese or Mandarin and have mild cognitive impairment (MCI), a slight decline in memory and thinking skills. It aims to help participants and their study partners manage daily memory challenges.
New York, New YorkAges 55 years+ - NCT07355348Recruiting
Cognitive support program for brain metastases
This study is testing a program to provide step-by-step cognitive support for adults whose cancer has spread to the brain. It aims to help people think more clearly and manage any memory or attention problems.
Toronto, OntarioAges 18 years+ - NCT06278532Recruiting
Validating psychosis assessment tools in Lithuanian
This trial tests whether three psychiatric questionnaires work well for people with schizophrenia or related disorders. If you are between 18 and 65 and have one of these diagnoses, joining may help improve care for others like you.
KaunasAges 18–65 - NCT07163013Recruiting
Digital therapy for teens with depression
This trial tests a digital therapy (a phone- or computer-based program) that teaches you skills to manage depression. It is designed for Chinese-speaking teens who have moderate to severe depression and are not currently receiving other treatment.
ChongqingAges 12–18 - NCT06859996Recruiting
Cognitive rehab study for memory and focus after mild brain injury
This study tests two different types of cognitive rehabilitation (education and problem-solving strategies) delivered via video appointments. It may help people with ongoing thinking and memory problems after a mild brain injury.
Seattle, WashingtonAges 18 years+ - NCT06632145Recruiting
A health promotion program for older adults with memory changes
This study tests a group program called Cog-Fun Ageing that helps older adults with memory changes stay active and healthy. If you have mild memory issues but can still think clearly, you may be able to join this Hebrew-speaking program.
JerusalemAges 60 years+ - NCT04731519Recruiting
Group treatment to help Veterans after a recent suicidal crisis
This trial studies a “recovery-oriented” group therapy for Veterans who had a suicide attempt or started planning within the last year. It aims to help reduce risk and improve coping and recovery after a post-acute suicidal episode.
The Bronx, New YorkAges 18 years+ - NCT04864080Recruiting
Online study to measure brain-related signals in pain or depression
This trial uses an online study platform to look for “cognitive biomarkers,” which are measurable patterns in thinking or brain-related responses. It compares people with pain or depression to healthy controls to see how these patterns differ and could help future research or care.
Minneapolis, MinnesotaAges 18 years+ - NCT05365347Recruiting
Program to reduce risky alcohol use in early psychosis
This study tests an intervention aimed at helping people with early psychosis who also drink in a risky way. It may help reduce problematic drinking during a critical early period of illness.
Halifax, Nova ScotiaAges 16–35 - NCT05999929Recruiting
Memory support system feasibility trial
This study tests a memory support system for people with mild cognitive impairment (MCI) and their care partners. It aims to see if the program is practical and helpful for managing memory challenges.
Ottawa, OntarioAges 50 years+ - NCT06067139Recruiting
Sleep therapy to lower diabetes risk in prediabetes
This study tests if a sleep-focused therapy (cognitive behavioral therapy for insomnia, or CBT-I) can lower diabetes risk in people with prediabetes and insomnia. Participants will receive online therapy sessions and wear a monitor to track blood sugar and sleep.
Portland, OregonAges 22–79 - NCT06480500RecruitingPhase 2
Online therapy and IV ketamine for severe depression with suicide risk
This study tests whether adding an online therapy (i-CBT) to intravenous (IV) ketamine is better than IV ketamine alone for people with treatment-resistant depression who are also thinking about suicide. You'll receive either ketamine or a comparison drug (midazolam), plus the online therapy, in a hospital setting.
Toronto, OntarioAges 21–65 - NCT06961916Recruiting
Brain stimulation to improve connections in schizophrenia
This study tests whether a non-invasive brain stimulation technique called TMS can improve brain connections in people with schizophrenia. It involves two types of MRI scans and several TMS sessions to see if it can help with thinking and symptoms.
Houston, TexasAges 18–60
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Common questions
- Are there clinical trials for cognitive health?
- Yes. Clin2 currently lists 283 recruiting cognitive health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.