Clinical trials
Cognitive Health clinical trials
Below are recruiting cognitive health clinical trials, each written for real people, not researchers. We’re tracking 271 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05394363Recruiting
Victoria children birth-cohort study with parent/guardian consent
This study follows children born in a specific 2-year window and their parents or guardians over time. It helps researchers understand how children and families change as they grow, which can guide future health supports in Victoria.
Parkville, VictoriaAges 1 day+ - NCT07173608Recruiting
Meditation and thinking skills for teen mental health
This study tests whether learning meditation and a thinking skill called cognitive reappraisal (changing how you think about a situation) can help teens feel better and handle stress. It is for teens aged 15-18 who live in the US and can visit a hospital in Boston.
Boston, MassachusettsAges 15–18 - NCT05509166Recruiting
Therapy for sexual-minority women dealing with anxiety or depression and drinking
This trial tests a type of supportive psychotherapy to help sexual-minority women improve mental well-being and reduce drinking. It may help if you’re experiencing depression or anxiety and have been drinking heavily, and you’re not already in certain kinds of treatment.
New York, New YorkAges 18 years+ - NCT07118722Recruiting
Quiet focus: mindfulness for pain and depression
This study compares two programs—mindfulness-based therapy and a general health program—to see which better helps older Black adults manage long-term pain and mild depression. It aims to find new ways to improve well-being.
Boston, MassachusettsAges 50–120 - NCT07056894Recruiting
Cognitive training for substance use in early psychosis
This study tests a computer-based cognitive training program to help people with early psychosis reduce their alcohol and cannabis use. The program is designed to improve thinking skills and may make it easier to cut back on substance use.
St. John's, Newfoundland and LabradorAges 16–30 - NCT06498011Recruiting
Training to improve arm and hand function after stroke
This study tests a new type of training that combines thinking, feeling, and moving to help improve arm and hand function after a stroke.
Toronto, OntarioAges 18 years+ - NCT06050603Recruiting
MRI guided brain stimulation study for memory
This study tests a new way to use brain stimulation guided by MRI to understand memory. It may help people with mild memory problems or healthy volunteers.
Toronto, OntarioAges 18–80 - NCT07164768Enrolling by invitation
Thinking and mood in kids with type 1 diabetes
This study looks at how type 1 diabetes affects thinking skills and emotional health in children, teens, and young adults. Both the young person and one of their parents will answer questions together.
Pune, MaharashtraAges 10–21 - NCT06989619Recruiting
Sleep and mindfulness program for older adults in residential housing
This study uses peer support and group activities to help older adults living in residential facilities improve their sleep and practice mindfulness (a type of focused relaxation). If you're 55+ and live in a residential building, you may be able to join.
Boston, MassachusettsAges 55 years+ - NCT06782321Recruiting
Virtual emotional support after stroke
This study tests a virtual program to help with emotional recovery like anxiety or sadness after a stroke. You can join from home using your own device.
Charleston, South CarolinaAges 21 years+ - NCT06757569Recruiting
New PET scan for detecting amyloid plaques in the brain
This study tests a newer, shorter PET scan to see if it can detect amyloid plaques (sticky protein clumps linked to memory loss) as well as the standard scan. It may help diagnose cognitive problems with less time in the scanner.
Toronto, OntarioAges 18 years+ - NCT06174038Recruiting
Hearing aids for memory and hearing loss study
This study tests whether hearing aids can help people with both hearing loss and early memory problems. It lasts for a period of time, and you will be asked to wear hearing aids daily.
New York, New YorkAges 55–75 - NCT06619769Recruiting
Online program for sexual health after gynecologic cancer
This trial tests an online program called eSense to help with sexual concerns after gynecologic cancer. It might help if you have had gynecologic cancer and are bothered by sexual difficulties.
Vancouver, British ColumbiaAges 19 years+ - NCT05336201RecruitingPhase 2
Brain training program for teens with sickle cell disease
This Phase 2 study tests a cognitive (thinking) training program to help teens with sickle cell disease prepare for the changes in their care as they grow older. It may help with skills like learning, attention, and planning for transition to adult care.
Birmingham, AlabamaAges 10–18 - NCT06032377Recruiting
Online therapy for sleep and brain health in older adults
This study tests an online talk therapy program (CBT) to help older adults with both sleep troubles and mild memory or thinking concerns. It's done from home, and aims to improve sleep and brain health.
Ottawa, OntarioAges 60–99 - NCT06024473Recruiting
Brain stimulation and virtual reality for memory loss
This study uses a combination of brain stimulation (rTMS) and virtual reality exercises to help improve memory and thinking. It is for people aged 55 and older who have Mild Cognitive Impairment (MCI), a condition that can affect memory but is not dementia.
Little Rock, ArkansasAges 55 years+ - NCT07364019Recruiting
Brain Health PRO: Online program to reduce dementia risk
This study tests an online program designed to lower your risk of developing dementia. It provides education and support to help you make brain-healthy changes.
Vancouver, British ColumbiaAges 50–80 - NCT04151693Recruiting
Group therapy for chronic fatigue syndrome
This trial tests a health-psychology–based rehabilitation program delivered in a group setting for people with chronic fatigue syndrome (ME/CFS). It may help by teaching strategies to cope with symptoms and improving daily functioning through structured group support.
LahtiAges 18–65 - NCT06036095RecruitingPhase 4
Comparing two types of anesthesia in older adults having surgery
This study compares two types of general anesthesia for older adults (70+) having planned non-heart, non-brain surgery that lasts at least 2 hours. The goal is to see which type might be better for preserving thinking and memory after surgery.
Portland, OregonAges 70–110 - NCT07489105Recruiting
Yoga for better thinking with heart failure
This trial tests if a yoga program can help improve memory and thinking in people with heart failure. It's designed for adults 55 and older who are not already doing yoga and are able to take part in gentle physical activity.
Auburn, AlabamaAges 55 years+ - NCT07420478Recruiting
TF-CBT for autistic youth with trauma
This trial tests trauma-focused therapy for autistic youth who have experienced trauma. It aims to see if this therapy helps reduce trauma-related distress.
Lebanon, New HampshireAges 6 years+ - NCT06597981Recruiting
Sport stacking program for mild dementia and caregivers
This trial tests a fun sport stacking activity for people with mild dementia and their family caregivers. It aims to improve well-being and connection through a simple, home-based program.
ChongqingAges 18 years+ - NCT06479174Recruiting
Cognitive strategies after stroke with family support
This study tests if combining cognitive exercises with a safe, mild brain stimulation can help improve memory and thinking after a stroke. It also looks at how shared family health history might affect recovery.
Albuquerque, New MexicoAges 18 years+ - NCT05131035Recruiting
Trial for thinking-speed training to lower psychosis risk
This study targets problems with “processing speed,” or how fast your brain handles information, to see if it can improve social functioning and lower the risk of developing full psychosis. It’s for people who are considered at high risk for psychosis but do not already have schizophrenia.
Glen Oaks, New YorkAges 14–20
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Common questions
- Are there clinical trials for cognitive health?
- Yes. Clin2 currently lists 271 recruiting cognitive health studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive health trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive health trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.