Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 2,033 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06345625Recruiting
Balance and walking with head movement in older adults
This study looks at how older adults keep their balance and walk when their head is moving. You may be asked to stand or walk while your head gently moves, so researchers can understand how your body reacts.
AntwerpAges 65–100 - NCT04770168Recruiting
Using Harry Potter activities to improve kids’ mental wellness
This trial tests whether a Harry Potter–based learning approach can improve children’s mental well-being, including anxiety and depression. You may be asked to fill out short questionnaires before and after the activities.
Toronto, OntarioAges 11–18 - NCT06447428Recruiting
Cognitive changes in late-life depression: a one-year study
This study follows older adults with depression to see how their thinking and memory might change over one year. It may help understand if early treatment can protect brain health.
Fuzhou, FujianAges 60 years+ - NCT07111286Recruiting
Imagining movements to help chronic low back pain
This trial tests whether imagining movements (motor imagery) can help improve daily function and reduce pain in people with chronic low back pain. You will participate in a rehabilitation program, and if you are in the motor imagery group, you will also practice mentally rehearsing specific movements.
DijonAges 18 years+ - NCT06746909Recruiting
Brain inflammation and imaging in older adults at risk for dementia
This study looks at how changes in the brain (like inflammation) relate to thinking and memory decline in older adults. It uses brain scans and computer tools to find early signs of dementia risk, with the goal of better preventing memory loss.
PisaAges 65–89 - NCT06098521Recruiting
CBT to prevent sexual reoffending for men in prison
This study tests if cognitive behavioral therapy (a talking therapy that changes thinking patterns) can help men in prison avoid committing another sexual offense after release. If you are a man serving time for a sexual crime and have an average or higher risk of reoffending, this therapy might be an option for you.
Stockholm, Stockholm CountyAges 18 years+ - NCT06288282Recruiting
Predicting pain and opioid misuse in chronic back pain
This study looks at how thinking and behavior affect long-term pain and opioid use in people with chronic lower back pain. It aims to find better ways to manage pain and prevent medication misuse.
New York, New YorkAges 18 years+ - NCT06315231RecruitingPhase 2
Stroke Recovery Thinking Trial for Recent Stroke Patients
This study tests an under-the-tongue tablet (edaravone dexborneol) to help thinking and memory problems that can happen after an ischemic stroke. It may help people who recently had a stroke and now have trouble with attention, memory, or planning.
Fuyang, AnhuiAges 40–80 - NCT05424406Recruiting
Studying sleep timing changes in people with night-shift disorder
This study looks at how changes in your body clock (circadian timing) relate to “shift work disorder” in people who work night shifts. It may help researchers understand what drives symptoms and how to better target treatment.
Novi, MichiganAges 18 years+ - NCT07500103Recruiting
Brain stimulation to help thinking and social skills in cerebellar disease
This trial tests a noninvasive brain stimulation method (tACS) to see if it can improve thinking, memory, and social abilities in people with cerebellar conditions. It may help if you have a cerebellar malformation or degenerative atrophy and are between 12 and 32 years old.
PaviaAges 12 years+ - NCT06658041Recruiting
A step-by-step program for mild to moderate depression
This trial tests a structured support program for adults with mild to moderate depression. It uses a team-based approach in primary care to help you feel better step by step.
Hong Kong, HONG KONGAges 45–59 - NCT07220265Recruiting
PKU carriers: How high phenylalanine affects the brain
This study looks at how carrying one copy of the PKU gene might affect thinking and brain health in adults. It will help researchers understand if mild changes in a substance called phenylalanine can impact memory, focus, and brain scans.
Columbia, MissouriAges 18–60 - NCT07577947Recruiting
Digital tracking to help treat pregnancy and postpartum depression
This study tests whether wearing an Apple Watch and using a smartphone app can help doctors better understand and treat depression during pregnancy and after birth. You'll receive depression treatment through the study while the app and watch track your daily patterns.
Los Angeles, CaliforniaAges 18 years+ - NCT07193732Enrolling by invitation
Islamic chair-work for grieving Muslims
This trial tests a culturally adapted therapy for Muslims who lost a loved one 6 months to 5 years ago and still feel unresolved tension with that person. The therapy uses chair-work exercises grounded in Islamic principles to help process grief.
Istanbul, BaşakşehirAges 18 years+ - NCT07086014Recruiting
Brain response to methamphetamine cues in men
This study uses brain scans to see how men with methamphetamine use disorder react to images or reminders of the drug. It aims to understand cravings and brain activity, which could help improve treatments.
New York, New YorkAges 18–60 - NCT06685380Recruiting
Cognitive Control During Sleep: Self-Awakening Study
This study looks at how our brains control waking up on purpose during sleep. It may help people who can train themselves to wake up at specific times.
Milan, ItalyAges 18–65 - NCT06721468Recruiting
Trout eating and brain health in kids and families
This study looks at how eating trout may affect brain health in children and their families. It has three parts for different age groups, and you may be asked to eat trout or answer questions online.
Moscow, IdahoAges 3 years+ - NCT07109245RecruitingPhase 4
Do antipsychotics block insulin action in the brain?
This study tests whether a single dose of a common antipsychotic medication affects how the brain responds to insulin, which could help explain weight gain and metabolic side effects. Healthy young adults will receive either the antipsychotic or a placebo, then have their brain activity measured with an MRI.
Toronto, OntarioAges 18–35 - NCT06677359Recruiting
Creatine and exercise for older adults
This study tests whether a creatine supplement, taken with or without a gentle exercise program, can help older adults stay stronger and more independent. It's designed for people aged 75 and older who can still walk.
Pamplona, NavarreAges 75 years+ - NCT07068971Enrolling by invitation
Sleep well at night for advanced cancer patients
This study tests a sleep program for people with advanced cancer who have trouble sleeping. It aims to help you sleep better at night.
DublinAges 18 years+ - NCT06375083RecruitingPhase 2
Computer therapy for suicide prevention and depression in Veterans
This trial tests two different computer-based therapy programs for Veterans: one for preventing suicide and one for treating depression. Both programs are designed to be done at home on your computer or tablet.
Aurora, ColoradoAges 18–65 - NCT07396220Enrolling by invitation
Psychotherapy with esketamine nasal spray for suicidal thoughts
This study tests combining a specific type of therapy (BCBT-SP) with esketamine nasal spray to help people with treatment-resistant depression who are having ongoing suicidal thoughts. The goal is to see if this combination can reduce suicidal ideation more effectively than either treatment alone.
San Diego, CaliforniaAges 18–70 - NCT07081269Recruiting
Fitness and thinking skills in Alzheimer's risk
This study looks at how physical fitness relates to thinking skills (like planning and focus) in people who may be at risk for Alzheimer's. You would do some simple fitness tests and thinking tasks to help researchers understand if staying fit can protect your brain.
TaipeiAges 50–70 - NCT06725953Recruiting
Remote exercise program for cancer survivors with or without diabetes
This study tests a 12-week home-based physical activity program to see if it helps cancer survivors who had chemotherapy and now have memory or thinking problems. It includes both survivors with type 2 diabetes and those without.
Oklahoma City, OklahomaAges 18 years+
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Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 2,033 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.