Clinical trials
Cognitive clinical trials
Below are recruiting cognitive clinical trials, each written for real people, not researchers. We’re tracking 2,028 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05934162Recruiting
Internet cognitive therapy for PTSD symptoms
This study tests whether therapist-guided cognitive-behavior therapy delivered over the internet can reduce PTSD symptoms. If you have PTSD and can use Swedish online materials, you may be able to take part without traveling to clinic visits.
StockholmAges 18 years+ - NCT05935241Recruiting
Program mPATH for sleep and activity in older adults
This trial tests a program (mPATH) to help older adults with sleep trouble by improving activity and exercise habits. It may be helpful if you have low income and want support building moderate exercise safely.
Baltimore, MarylandAges 65 years+ - NCT05936619Recruiting
Brain-computer device for communication in people with paralysis
This trial tests a “brain-computer interface” that aims to help people with paralysis communicate. It involves surgery to place a device and uses frequent follow-ups, including daily help from a caregiver to watch the surgical area and behavior.
Dallas, TexasAges 18–65 - NCT05943171Recruiting
App-based CBT for substance dependence and relationship aggression
This study tests an app-guided version of CBT (a structured talk-therapy approach) against standard CBT to help people with substance dependence and recent verbal aggression in an intimate relationship. You may be screened to see if you fit both the substance use and relationship aggression parts of the trial.
Rochester, New YorkAges 18–65 - NCT05943834Recruiting
Voice testing to detect early memory and mood changes
This trial studies whether automated analysis of your voice and speech can help detect early signs of Alzheimer’s disease and mood (affective) problems. It may help identify changes sooner, using voice and questionnaire information from people who are cognitively healthy to very mildly affected.
NiceAges 50–100 - NCT05945602Recruiting
Using brain signals to guide cognitive rehab in psychosis
This study looks at brain-wave or related “brain signal” measurements to better guide cognitive rehabilitation (thinking and memory skills). It may help people with long-term psychotic disorders, and it also may include healthy comparison volunteers to understand the signals.
San Diego, CaliforniaAges 18–75 - NCT05958381Recruiting
Brain stimulation for memory problems in relapsing MS
This trial studies a noninvasive brain stimulation treatment to improve memory (specifically memory recall) in people with relapsing-remitting multiple sclerosis (RRMS). It may help if your memory testing shows a “retrieval” problem, and if you’re able to follow the study treatment and safety requirements.
Richardson, TexasAges 18–65 - NCT05962424RecruitingPhase 1
Study of brain activity during thinking using electrode recordings
This Phase 1 study records electrical signals from the brain while you perform thinking tasks. The goal is to better understand how human brain circuits work during cognition, and the study may help future treatments.
Palo Alto, CaliforniaAges 18 years+ - NCT05965310Recruiting
Virtual psychology support for ACL repair recovery
This study tests a virtual (online) psychological program to help people recover after ACL ligament surgery. It focuses on first-time ACL repairs and aims to improve how patients cope during recovery.
Detroit, MichiganAges 13 years+ - NCT05980117RecruitingPhase 4
Remimazolam sedation for cataract surgery
This study tests a sedative, remimazolam, for older adults having their first cataract surgery. It aims to see if it helps keep patients comfortable and calm without needing general anesthesia.
Los Angeles, CaliforniaAges 65 years+ - NCT05982730Recruiting
Segway training for balance and thinking in Parkinson's
This study tests whether practicing balance on a Segway can improve walking and thinking for people with moderate Parkinson's. You will train on a Segway while getting special sensory cues, and researchers will see if it helps your motor skills and cognitive function.
Dallas, TexasAges 50–85 - NCT05983809Recruiting
Balance and walking rehab using technology for MS
This trial tests a new type of balance and walking training for people with multiple sclerosis. It uses technology to help improve your stability and gait, which may help you move more safely and confidently.
Roma, RMAges 18–65 - NCT05990790RecruitingPhase 4
Comparing anesthetics and their effect on confusion after surgery
This study compares three different anesthesia medicines to see which one might lower the chance of confusion or delirium after major surgery. If you are 65 or older and having a long, planned non-heart surgery, this trial could help determine the safest option for you.
InnsbruckAges 65 years+ - NCT05992831Recruiting
Transcranial magnetic stimulation for mild cognitive impairment
This trial tests whether transcranial magnetic stimulation (a noninvasive brain stimulation technique) can help people with mild cognitive impairment (MCI). You and a close contact, like a spouse or friend, will both take part in the study over several sessions.
Charleston, South CarolinaAges 60–85 - NCT05999929Recruiting
Memory support system feasibility trial
This study tests a memory support system for people with mild cognitive impairment (MCI) and their care partners. It aims to see if the program is practical and helpful for managing memory challenges.
Ottawa, OntarioAges 50 years+ - NCT06004414Recruiting
SilverCloud mental health app study for high school students
This study tests a mental health app called SilverCloud in high school students who are feeling anxious or depressed. It aims to see if the app can help improve their mood and wellbeing.
New Brunswick, New JerseyAges 13–22 - NCT06004804Recruiting
Video group therapy for chronic pain in older Veterans
This study tests whether group therapy sessions held over video can help older Veterans manage chronic muscle or joint pain. It focuses on teaching practical skills to reduce pain and improve quality of life.
West Los Angeles, CaliforniaAges 60–95 - NCT06016309Recruiting
Understanding Thinking, Energy, Mood, and Behavior in MS
This study looks at how multiple sclerosis affects thinking, energy, mood, and behavior. It uses simple tests and questionnaires to understand your unique profile, which may help tailor future care.
Groningen, Provincie GroningenAges 18–70 - NCT06021197RecruitingPhase 2
NMDA-enhancing treatment for cognitive symptoms in schizophrenia
This study tests a new treatment that may help with thinking and memory problems in people with schizophrenia. It is for people whose schizophrenia symptoms are stable and who are already on a steady medication.
TaichungAges 18–65 - NCT06030154Recruiting
Boosting positive feelings for people with alcohol use disorder
This study tests a program designed to help people with alcohol use disorder who also struggle with low mood or anxiety. It aims to increase positive emotions, which may make it easier to reduce drinking.
Tulsa, OklahomaAges 18–65 - NCT06036095RecruitingPhase 4
Comparing two types of anesthesia in older adults having surgery
This study compares two types of general anesthesia for older adults (70+) having planned non-heart, non-brain surgery that lasts at least 2 hours. The goal is to see which type might be better for preserving thinking and memory after surgery.
Portland, OregonAges 70–110 - NCT06036147Recruiting
Concussion Recovery Program for Teens
This study tests a remote program to help teens ages 11 to 18 recover from a concussion that happened 1 to 12 months ago. You'll learn ways to manage symptoms like headaches, tiredness, or trouble focusing, all from home.
Dallas, TexasAges 11–18 - NCT06036706Recruiting
Radiation types and thinking skills for skull base meningioma
This study compares different radiation methods for treating a slow-growing, non-cancerous brain tumor at the base of the skull. It aims to see which approach best protects memory and thinking abilities.
CaenAges 20–65 - NCT06037785Recruiting
Self-management support after an ICD shock
This study tests a self-management program to help people who have received a shock from their implantable cardioverter-defibrillator (ICD). The goal is to see if this program can improve recovery and well-being after a shock.
Seattle, WashingtonAges 18 years+
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Common questions
- Are there clinical trials for cognitive?
- Yes. Clin2 currently lists 2,028 recruiting cognitive studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.