Clinical trials
Colon Cancer clinical trials
Below are recruiting colon cancer clinical trials, each written for real people, not researchers. We’re tracking 292 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07255729Recruiting
Blood Test for Colon Cancer Staging
This study looks at a new blood test that may help doctors better understand how far colon cancer has spread. By testing a sample of your blood (taken before surgery), researchers hope to find patterns that predict the stage of cancer and help guide treatment decisions.
Duarte, CaliforniaAges 18 years+ - NCT06715839Recruiting
Digestive cancer imaging study with targeted antibodies
This trial uses a special imaging test (PET scan) to find digestive system cancers. It uses molecules that attach to cancer cells so they light up on the scan, which may help doctors see tumors more clearly.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06746012Recruiting
Health app study for colorectal cancer survivors and their caregivers
This study tests a mobile health program to help colorectal cancer survivors and their family caregivers stick to healthy lifestyle habits. It's for survivors who are at least 6 months past treatment and have a smartphone.
Columbus, OhioAges 18 years+ - NCT06830239RecruitingPhase 2
Neoadjuvant dostarlimab for resectable stage III colon cancer
This trial tests an investigational immunotherapy drug called dostarlimab given before surgery for colon cancer. It is for people whose tumor is MMR-proficient (also called MSS) and is large enough or has spread to nearby lymph nodes but not to other parts of the body. The goal is to see if this treatment can shrink the tumor before surgery.
LeuvenAges 18 years+ - NCT06940947RecruitingPhase 3
Endoscopy or surgery for early colon cancer
This trial compares a newer, less invasive endoscopic procedure with standard surgery for people who have a small, early-stage colon cancer. The goal is to see if the endoscopic treatment is as effective as surgery while being gentler on the body.
GdanskAges Any age - NCT06958926Recruiting
Study of colon cancer that returns after surgery
This study looks at colon cancer that comes back in the same area after surgery. It may help doctors understand how to better treat this type of recurrence.
HsinchuAges 18 years+ - NCT06960291Recruiting
EXCEL Exercise Program for Cancer Patients in Canada
This study tests a national exercise program called EXCEL for people with cancer. It helps you start or continue safe physical activity to manage side effects and improve your well-being.
Calgary, AlbertaAges 18 years+ - NCT07140679RecruitingPhase 2
Immunotherapy after surgery for certain colon cancers
This trial tests whether the immunotherapy drug toripalimab can lower the risk of colon cancer coming back after surgery. It is for people with a specific genetic feature called mismatch repair deficiency (dMMR) in their tumor, and whose cancer was at a higher stage (stage IIB, IIC, or III).
Atlanta, GeorgiaAges 18 years+ - NCT07179692RecruitingPhase 1
CEA-targeted CAR-T therapy for advanced solid tumors
This trial tests a type of immunotherapy called CAR-T, which is designed to recognize and attack cancer cells that have a protein called CEA on their surface. It's for people with advanced cancers like colorectal, esophageal, gastric, pancreatic, lung, or bile duct cancer who have tried at least two standard treatments.
Hefei, AnhuiAges 18 years+ - NCT07059884Recruiting
Exercise program to help people with cancer stay active
This trial tests a distance-based exercise program designed to help people on chemotherapy maintain their physical function and prevent disability. It is for patients with certain cancers who are working full-time and can participate in moderate physical activity.
Dublin, CaliforniaAges 18 years+ - NCT07387263Recruiting
Digital tool for genetic testing in cancer care
This study tests a digital tool that helps cancer doctors offer genetic testing to more patients. If you've already had genetic testing started by your oncologist, you may be able to join.
Toronto, OntarioAges 18 years+ - NCT00451022Recruiting
Follow-up study for people who received gene-carrying viral vaccines
This is a follow-up study for adults who previously received certain viral vaccines that carry genes (such as vaccinia or fowlpox) through NCI trials or partner sites. The goal is to store and use your leftover samples for future research that may help doctors understand these treatments better.
Bethesda, MarylandAges 18 years+ - NCT00034216Recruiting
Blood Collection Study for Cancer Patients and Healthy Volunteers
This study collects blood samples from people with cancer and healthy volunteers to help researchers understand cancer better. Your blood will be used for laboratory studies that may improve future cancer treatments.
Bethesda, MarylandAges 18 years+ - NCT02012699Recruiting
Cancer registry for people with or at risk of cancer
This trial collects health information and samples (a “cancer repository”) to help researchers study cancer and cancer risk. You may be able to join if you’ve had cancer before or if you’re at higher risk or have concerning findings.
Greenwood Village, ColoradoAges 19–110 - NCT02172651RecruitingEarly Phase 1
Vitamin D during early colon cancer or liver surgery
This trial studies whether taking higher-dose vitamin D3 around the time of colon cancer (or colon cancer with resectable liver metastases) surgery improves outcomes. It focuses on safety and possible effects on cancer-related health after surgery.
Boston, MassachusettsAges 18 years+ - NCT07405476RecruitingPhase 2
Zanidatamab before surgery for HER2 positive colon or rectal cancer
This trial tests if the drug zanidatamab, given before surgery, can help treat colon or rectal cancer that has a specific marker called HER2. The goal is to see if this approach can shrink tumors and improve outcomes for people whose cancer has not spread to other parts of the body.
Atlanta, GeorgiaAges 18 years+ - NCT07405931Recruiting
Managing chemo side effects with phone calls and a smartphone app
This study tests whether checking in by phone or smartphone app can help manage chemotherapy side effects. If you are starting a new chemo for stomach, lung, breast, or colon cancer, this program may support you from home.
BusanAges 19 years+ - NCT07407465RecruitingPhase 2
Study of a new drug combo for advanced HER2-positive colorectal cancer
This trial tests a combination of three drugs (trastuzumab deruxtecan, capecitabine, and bevacizumab) as the first treatment for people with HER2-positive colorectal cancer that has spread or cannot be removed by surgery. The goal is to see if this combination can shrink tumors and help patients live longer.
LyonAges 18 years+ - NCT07432399RecruitingPhase 2
Lidocaine or dexamethasone before colon cancer surgery
This study tests whether giving lidocaine or a high-dose steroid before colon cancer surgery can improve immune function and recovery. The goal is to find a simple, safe way to help your body respond better during surgery.
LjubljanaAges 18 years+ - NCT07450612Recruiting
Blood test and AI for early colorectal cancer detection
This study uses a simple blood test (liquid biopsy) and computer analysis to find early signs of colorectal cancer, precancerous growths, and Lynch syndrome. It aims to improve early detection and monitor for any remaining cancer after treatment.
Milan, LombardyAges 18 years+ - NCT07595874RecruitingPhase 2
New Immunotherapy Drugs Before Surgery for Advanced Colorectal Cancer
This trial tests two immunotherapy drugs (botensilimab and balstilimab) given before surgery to treat advanced colorectal cancer that can be removed. The goal is to help the immune system fight cancer cells and improve outcomes after surgery.
Goodyear, ArizonaAges 18 years+ - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT03976960Recruiting
Database study for colon cancer surgery patients
This study collects clinical and lab information from people who have surgery for colon cancer (or certain precancer growths) and related spread to organs. It may help researchers better understand colon cancer and improve future care, but it is not a new medication trial.
Montpellier, HéraultAges 18 years+ - NCT04527861Recruiting
Minimally invasive single-incision surgery for colon cancer
This trial compares a single-incision laparoscopic operation versus the usual laparoscopic operation for colorectal (colon or “high rectum”) cancer. It looks at cancer outcomes and may help determine which approach is safer and works better for the right patients.
Lanzhou, GansuAges 18–85
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Common questions
- Are there clinical trials for colon cancer?
- Yes. Clin2 currently lists 292 recruiting colon cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colon cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colon cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.