Clinical trials
Colorectal Cancer (Locally Advanced or Metastatic) clinical trials
Below are recruiting colorectal cancer (locally advanced or metastatic) clinical trials, each written for real people, not researchers. We’re tracking 5,511 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07107594Recruiting
Exercise, nutrition and support program for early breast cancer
This trial tests a program combining physical exercise, psychological support and nutritional advice before chemotherapy to see if it can improve treatment response in early breast cancer patients.
BarcelonaAges 18 years+ - NCT07112170Recruiting
Radiation to slow melanoma growth after initial treatment
This study tests whether giving precise radiation to a limited number of growing spots can help control melanoma that has spread but is otherwise stable on immunotherapy or targeted therapy. You may join if you have up to 10 growing spots outside the brain that can be safely treated with focused radiation.
Toronto, OntarioAges 18 years+ - NCT07097142RecruitingPhase 3
Shorter radiation for bladder cancer with chemo
This trial tests if a shorter course of radiation therapy works as well as the usual longer course for people with bladder cancer who are also receiving standard chemotherapy. The goal is to see if shorter treatment can reduce side effects while still being effective.
Fort Smith, ArkansasAges 18 years+ - NCT07102381RecruitingPhase 2
Zanidatamab plus chemo before surgery for HER2+ breast cancer
This trial tests a new drug called zanidatamab combined with chemotherapy to shrink HER2-positive breast cancer before surgery. It may help improve treatment outcomes for people with stage 2 or 3 breast cancer that has not spread.
Long Beach, CaliforniaAges 18 years+ - NCT03201861RecruitingPhase 3
Cisplatin added after surgery for high-risk breast cancer
This trial checks whether adding cisplatin to standard chemotherapy after surgery helps women with high-risk early-stage breast cancer lower the chance of the cancer coming back. You would be followed to see how well treatment works and whether it is tolerated.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT06975384Recruiting
Sleep and lung cancer treatment outcome study
This study looks at how sleep disturbances affect how well lung cancer treatments work. It may help doctors understand if improving sleep can lead to better treatment results.
Changsha, HunanAges 18 years+ - NCT07080476Recruiting
Kinesio taping for chronic swelling after breast cancer
This trial tests whether Kinesio taping, a special type of elastic tape, can reduce long-term swelling in the breast or upper body (trunk) after breast cancer treatment. If you have had breast cancer and still have swelling lasting more than six months, this study may help find a new way to manage that swelling.
AntwerpAges 18 years+ - NCT07069595RecruitingPhase 2
Blood test for breast cancer survivors at risk of recurrence
This trial uses a simple blood test to look for leftover cancer DNA in people with triple-negative breast cancer who still have disease after chemotherapy and surgery. It aims to catch any early signs of the cancer coming back.
Chapel Hill, North CarolinaAges 18 years+ - NCT06398314Recruiting
Palliative radiation for pelvic tumor symptoms
This trial tests a type of radiation to help relieve symptoms like pain, bleeding, or other discomfort from tumors in the pelvic area. It is for people whose cancer has spread or cannot be cured, and who are not able to have stronger treatments.
ÅlesundAges 18 years+ - NCT07057427RecruitingPhase 3
Nab-paclitaxel vs TCbHP for HER2-positive early breast cancer
This trial compares two different drug combinations given before surgery to shrink HER2-positive breast cancer tumors. The goal is to see which combination works better and has fewer side effects.
Zhengzhou, HenanAges 18–70 - NCT07062003Recruiting
Skin or soft tissue tumor radiation therapy using minibeams
This study tests a new type of radiation therapy, called minibeam radiation, for skin or soft tissue tumors that have come back or spread. The goal is to see if this approach can help shrink tumors while possibly sparing healthy tissue, and it's designed for people who may benefit from palliative treatment to relieve symptoms.
Rochester, MinnesotaAges 18 years+ - NCT07042100RecruitingPhase 1
Safety study of SBO-154 for advanced solid tumors
This trial tests a new drug called SBO-154 to see if it is safe and tolerable for people with advanced solid tumors that have not responded to standard treatments. It may be an option if you have few or no other treatment choices.
Scottsdale, ArizonaAges 18 years+ - NCT07037576Recruiting
Breast reconstruction study for patients needing radiation after mastectomy
This study compares two types of breast reconstruction for women who need radiation therapy after their mastectomy: one-stage reconstruction using a permanent implant placed in front of the chest muscle, versus the standard two-stage approach where a tissue expander is used first and replaced with a permanent implant later. The goal is to see which method works better and is safer for patients who require post-mastectomy radiation.
Henan, HenanAges 18–70 - NCT07027124RecruitingPhase 2
High-risk prostate cancer treatment before and after surgery
This trial tests a combination of hormone therapy, a targeted pill (Darolutamide), and an immunotherapy drug (Pembrolizumab) before and after surgery for men with high-risk prostate cancer that has specific genetic features. The goal is to see if this approach helps prevent the cancer from coming back.
New York, New YorkAges 18 years+ - NCT07030686Recruiting
Exercise and quality of life in cancer survivors
This study looks at how exercise habits are linked to how cancer survivors feel and their health outcomes. It may help understand if starting to exercise improves well-being.
Los Angeles, CaliforniaAges 18 years+ - NCT07025785Recruiting
Testing for tumor DNA in blood after early-stage breast cancer surgery
This study looks for tiny bits of tumor DNA in your blood after surgery to see if it can help guide future treatment. It's for people who had surgery first (not chemotherapy before surgery) and have not seen the cancer spread.
Chapel Hill, North CarolinaAges 18 years+ - NCT07015138Recruiting
Comparing two radiation approaches for prostate cancer that has spread a little
This trial is testing whether giving radiation to all spots of cancer that show up on a PSMA PET scan works better than giving radiation only to the main tumor in the prostate. It is for men whose prostate cancer has spread to a few other places (up to 10 spots).
Beijing, Beijing MunicipalityAges 18–85 - NCT06990061Recruiting
Radiation therapy for BCG-resistant bladder CIS
This trial tests radiotherapy (high-energy X-rays) for a specific type of early-stage bladder cancer (CIS) that hasn't gone away after BCG treatment. It's for people who can't or choose not to have bladder removal surgery.
Anderlecht, Brussels CapitalAges 18 years+ - NCT06964009RecruitingPhase 1
New drug plus paclitaxel for resistant ovarian cancer
This trial tests a new drug called DT2216 combined with the chemotherapy drug paclitaxel for ovarian cancer that has stopped responding to platinum-based chemo. The goal is to see if this combination can shrink or slow the cancer, and to find a safe dose.
Boston, MassachusettsAges 18 years+ - NCT06968871Recruiting
Gentler Pap test for cervical cancer screening
This trial tests a new, gentler Pap test to see if it makes screening more comfortable and easier for women. If you're a woman 25 or older and not pregnant or on your period, you might be able to join.
DouliuAges 25 years+ - NCT06957431RecruitingPhase 1
Zanzalintinib and eribulin for advanced leiomyosarcoma and liposarcoma
This trial tests a combination of two drugs, zanzalintinib and eribulin, for people with advanced leiomyosarcoma or liposarcoma that has progressed after prior treatment. The goal is to see if this combination can help shrink or slow the growth of these sarcomas.
St Louis, MissouriAges 18 years+ - NCT06935097Enrolling by invitation
Mediterranean diet study for Black and Hispanic men with prostate cancer
This study tests whether a Mediterranean diet can help men with prostate cancer. You'll receive guidance on following this diet to see if it improves your health.
Houston, TexasAges 18 years+ - NCT06934057RecruitingPhase 4
Cabozantinib and Nivolumab for older adults with kidney cancer
This trial is testing a combination of two drugs, cabozantinib and nivolumab, in people aged 70 or older who have advanced kidney cancer that hasn't been treated yet. The goal is to see if this combination works well and is safe for older patients.
AngersAges 70 years+ - NCT06927180RecruitingPhase 2
Study of SHR-A1811 plus pertuzumab before surgery for HER2+ breast cancer
This trial tests a combination of two targeted drugs (SHR-A1811 and pertuzumab) given before surgery to shrink HER2-positive breast cancer. It aims to see if this approach improves outcomes for patients with early-stage but high-risk disease.
Zhengzhou, HenanAges 18–70
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Common questions
- Are there clinical trials for colorectal cancer (locally advanced or metastatic)?
- Yes. Clin2 currently lists 5,511 recruiting colorectal cancer (locally advanced or metastatic) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal cancer (locally advanced or metastatic) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal cancer (locally advanced or metastatic) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Locally Advanced or Metastatic Breast Cancer
- Locally Advanced or Metastatic Non-small Cell Lung Cancer
- Locally Advanced Colorectal Cancer
- Lung Cancer (Locally Advanced or Metastatic)
- Liver Cancer (Locally Advanced or Metastatic)
- Metastatic Colorectal Cancer
- Locally Advanced Rectal Cancer
- Metastatic Colorectal Cancer (CRC)
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.